Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           19     869
NP_036462                                                              19     869
NP_001243397                                                           19     869
XP_005269721                                                           19     869
NP_004925                                                              17    4312
XP_006714498                                                           17    4312
XP_005248285                                                           17    4312
NP_067640                                                              16    7355
NP_055458                                                              16    7355
XP_005247748                                                           16    7355
XP_005247747                                                           16    7355
NP_004937                                                              16    7355
NP_001273767                                                           15    9605
NP_001501                                                              15    9605
NP_001186184                                                           15    9605
NP_001186182                                                           15    9605
NP_001186180                                                           15    9605
NP_001012411                                                           15    9605
NP_001012409                                                           15    9605
NP_004636                                                              15    9605
NP_001138775                                                           15    9605
NP_653287                                                              15    9605
NP_001012413                                                           15    9605
NP_079410                                                              15    9605
NP_002257                                                              15    9605
NP_001012410                                                           15    9605
NP_001186185                                                           15    9605
NP_612493                                                              15    9605
NP_001012412                                                           15    9605
NP_001186181                                                           15    9605
NP_001186183                                                           15    9605
NP_001254524                                                           15    9605
NP_001254523                                                           15    9605
NP_055506                                                              15    9605
NP_862820                                                              15    9605
NP_001184188                                                           15    9605
NP_036513                                                              15    9605
XP_006726250                                                           15    9605
XP_006726210                                                           15    9605
XP_006726112                                                           15    9605
XP_006726013                                                           15    9605
XP_006725925                                                           15    9605
XP_006725825                                                           15    9605
XP_006725698                                                           15    9605
XP_005256233                                                           15    9605
XP_005256232                                                           15    9605
XP_005256231                                                           15    9605
XP_005256229                                                           15    9605
XP_005256228                                                           15    9605
XP_005256227                                                           15    9605
XP_006721346                                                           15    9605
XP_005256226                                                           15    9605
XP_006721345                                                           15    9605
XP_006721344                                                           15    9605
XP_006721343                                                           15    9605
XP_005256225                                                           15    9605
XP_006719425                                                           15    9605
XP_006719424                                                           15    9605
XP_005248763                                                           15    9605
XP_005248762                                                           15    9605
XP_005248761                                                           15    9605
XP_006714258                                                           15    9605
XP_006713050                                                           15    9605
XP_006713049                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           NILLR SKK
Sbjct: 470 NILLRHSKK 478
>NP_036462
          Length = 2073

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           NILLR SKK
Sbjct: 762 NILLRHSKK 770
>NP_001243397
          Length = 1890

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           NILLR SKK
Sbjct: 579 NILLRHSKK 587
>XP_005269721
          Length = 2073

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           NILLR SKK
Sbjct: 762 NILLRHSKK 770
>NP_004925
          Length = 790

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ILLRRSKK 9
           I LRRSKK
Sbjct: 634 ITLRRSKK 641
>XP_006714498
          Length = 790

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ILLRRSKK 9
           I LRRSKK
Sbjct: 634 ITLRRSKK 641
>XP_005248285
          Length = 790

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ILLRRSKK 9
           I LRRSKK
Sbjct: 634 ITLRRSKK 641
>NP_067640
          Length = 589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           N+L+ R+KK
Sbjct: 421 NLLVERNKK 429
>NP_055458
          Length = 1163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILLRRSKK 9
           +LLR SKK
Sbjct: 151 VLLRSSKK 158
>XP_005247748
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           N+L+ R+KK
Sbjct: 306 NLLVERNKK 314
>XP_005247747
          Length = 620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           N+L+ R+KK
Sbjct: 452 NLLVERNKK 460
>NP_004937
          Length = 1830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ILLRRSKK 9
            + LRRSKK
Sbjct: 1693 VKLRRSKK 1700
>NP_001273767
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLRRSKK 9
           +LLRR++K
Sbjct: 452 VLLRRAEK 459
>NP_001501
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLRRSKK 9
           +LLRR++K
Sbjct: 547 VLLRRAEK 554
>NP_001186184
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 247 LRRSKK 252
>NP_001186182
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 264 LRRSKK 269
>NP_001186180
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 516 LRRSKK 521
>NP_001012411
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 264 LRRSKK 269
>NP_001012409
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 516 LRRSKK 521
>NP_004636
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           N+ LR++KK
Sbjct: 103 NLSLRKAKK 111
>NP_001138775
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLRRSKK 9
           LLRRSK+
Sbjct: 127 LLRRSKE 133
>NP_653287
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LLRRSKK 9
           LLRRSK+
Sbjct: 121 LLRRSKE 127
>NP_001012413
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 247 LRRSKK 252
>NP_079410
          Length = 2881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>NP_002257
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  NILLRRSKK 9
          N+ LR++KK
Sbjct: 35 NVELRKAKK 43
>NP_001012410
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 516 LRRSKK 521
>NP_001186185
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 247 LRRSKK 252
>NP_612493
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 247 LRRSKK 252
>NP_001012412
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 264 LRRSKK 269
>NP_001186181
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 516 LRRSKK 521
>NP_001186183
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 264 LRRSKK 269
>NP_001254524
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           N+L+ RSK+
Sbjct: 476 NMLMERSKE 484
>NP_001254523
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           N+L+ RSK+
Sbjct: 476 NMLMERSKE 484
>NP_055506
          Length = 1485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NILLRRSKK 9
           NI++RR  K
Sbjct: 654 NIIMRRKPK 662
>NP_862820
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 540 LRRSKK 545
>NP_001184188
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 396 LRRSKK 401
>NP_036513
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 539 LRRSKK 544
>XP_006726250
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLRRSKK 9
          LLRRSK+
Sbjct: 31 LLRRSKE 37
>XP_006726210
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLRRSKK 9
          LLRRSK+
Sbjct: 31 LLRRSKE 37
>XP_006726112
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLRRSKK 9
          LLRRSK+
Sbjct: 31 LLRRSKE 37
>XP_006726013
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLRRSKK 9
          LLRRSK+
Sbjct: 31 LLRRSKE 37
>XP_006725925
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLRRSKK 9
          LLRRSK+
Sbjct: 31 LLRRSKE 37
>XP_006725825
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLRRSKK 9
          LLRRSK+
Sbjct: 31 LLRRSKE 37
>XP_006725698
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLRRSKK 9
          LLRRSK+
Sbjct: 31 LLRRSKE 37
>XP_005256233
          Length = 2391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLRRSK 8
           ILLRR+K
Sbjct: 875 ILLRRTK 881
>XP_005256232
          Length = 2424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILLRRSK 8
           ILLRR+K
Sbjct: 908 ILLRRTK 914
>XP_005256231
          Length = 2573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256229
          Length = 2881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256228
          Length = 2882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256227
          Length = 2897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006721346
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256226
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006721345
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006721344
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006721343
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_005256225
          Length = 2898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    ILLRRSK 8
            ILLRR+K
Sbjct: 1382 ILLRRTK 1388
>XP_006719425
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           N+L+ RSK+
Sbjct: 277 NMLMERSKE 285
>XP_006719424
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLRRSKK 9
           N+L+ RSK+
Sbjct: 508 NMLMERSKE 516
>XP_005248763
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 487 LRRSKK 492
>XP_005248762
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 487 LRRSKK 492
>XP_005248761
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 540 LRRSKK 545
>XP_006714258
          Length = 994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLRRSKK 9
           +LLRR++K
Sbjct: 534 VLLRRAEK 541
>XP_006713050
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 516 LRRSKK 521
>XP_006713049
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRSKK 9
           LRRSKK
Sbjct: 516 LRRSKK 521
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.139    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,810
Number of extensions: 681
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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