Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              20     299
XP_005265800                                                           20     299
XP_006714103                                                           20     299
XP_006714102                                                           20     299
NP_004068                                                              17    3301
NP_653267                                                              17    4312
NP_036286                                                              16    5631
NP_001158095                                                           16    5631
NP_002600                                                              16    5631
NP_000213                                                              16    5631
NP_001087241                                                           16    5631
NP_776176                                                              16    5631
NP_055748                                                              16    5631
NP_001070676                                                           16    5631
NP_001070675                                                           16    5631
NP_001070674                                                           16    5631
NP_001177131                                                           16    5631
NP_057295                                                              16    5631
NP_001177978                                                           16    5631
XP_005255954                                                           16    5631
XP_006721241                                                           16    5631
XP_005255953                                                           16    5631
XP_005268521                                                           16    5631
XP_006714210                                                           16    5631
XP_006714209                                                           16    5631
XP_005262911                                                           16    5631
XP_005262909                                                           16    5631
XP_005262908                                                           16    5631
XP_005262907                                                           16    5631
XP_006714208                                                           16    5631
XP_005262906                                                           16    5631
XP_006714207                                                           16    5631
XP_006714206                                                           16    5631
XP_006714205                                                           16    5631
XP_006714204                                                           16    5631
XP_005262904                                                           16    5631
XP_005265799                                                           16    5631
XP_005265798                                                           16    5631
XP_005265797                                                           16    5631
NP_001177130                                                           16    5631
NP_065681                                                              16    7355
NP_066124                                                              16    7355
NP_056505                                                              16    7355
NP_001230242                                                           16    7355
NP_001191375                                                           16    7355
NP_060817                                                              16    7355
XP_006717999                                                           16    7355
XP_006717822                                                           16    7355
XP_006717821                                                           16    7355
XP_005269749                                                           16    7355
XP_006717820                                                           16    7355
XP_006712484                                                           16    7355
XP_006712483                                                           16    7355
XP_005246521                                                           16    7355
NP_001191376                                                           16    7355
NP_065081                                                              16    7355
NP_005498                                                              15    9605
NP_001276976                                                           15    9605
NP_001276975                                                           15    9605
NP_004110                                                              15    9605
NP_056305                                                              15    9605
NP_001155238                                                           15    9605
NP_689837                                                              15    9605
NP_001229306                                                           15    9605
NP_067646                                                              15    9605
NP_000678                                                              15    9605
NP_775871                                                              15    9605
XP_006724141                                                           15    9605
XP_005260374                                                           15    9605
XP_005260373                                                           15    9605
XP_005271971                                                           15    9605
XP_006711542                                                           15    9605
XP_006711541                                                           15    9605
XP_005245460                                                           15    9605
>NP_006197
          Length = 1089

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NILLAQGKI 9
           N+LLAQGKI
Sbjct: 823 NVLLAQGKI 831
>XP_005265800
          Length = 1089

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NILLAQGKI 9
           N+LLAQGKI
Sbjct: 823 NVLLAQGKI 831
>XP_006714103
          Length = 1111

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NILLAQGKI 9
           N+LLAQGKI
Sbjct: 845 NVLLAQGKI 853
>XP_006714102
          Length = 1114

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   NILLAQGKI 9
           N+LLAQGKI
Sbjct: 848 NVLLAQGKI 856
>NP_004068
          Length = 466

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NILLAQGK 8
           N+LL QGK
Sbjct: 386 NVLLEQGK 393
>NP_653267
          Length = 4753

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    NILLAQGKI 9
            NI+ AQGK+
Sbjct: 3818 NIVRAQGKL 3826
>NP_036286
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NILLAQGK 8
           NILL QG+
Sbjct: 576 NILLPQGR 583
>NP_001158095
          Length = 825

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NILLAQGK 8
           NILL QG+
Sbjct: 576 NILLPQGR 583
>NP_002600
          Length = 1106

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NILLAQGKI 9
           N+L+ +GK+
Sbjct: 831 NVLICEGKL 839
>NP_000213
          Length = 976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           NILL  G+I
Sbjct: 797 NILLTHGRI 805
>NP_001087241
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           NILL  G+I
Sbjct: 793 NILLTHGRI 801
>NP_776176
          Length = 468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 333 VLLTQGKV 340
>NP_055748
          Length = 1220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>NP_001070676
          Length = 1205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>NP_001070675
          Length = 1220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>NP_001070674
          Length = 1106

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>NP_001177131
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 239 VLLTQGKV 246
>NP_057295
          Length = 1181

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 716 NLLAAQGSI 724
>NP_001177978
          Length = 1200

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 750 NLLAAQGSI 758
>XP_005255954
          Length = 367

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 139 VLLTQGKV 146
>XP_006721241
          Length = 372

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 139 VLLTQGKV 146
>XP_005255953
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 356 VLLTQGKV 363
>XP_005268521
          Length = 1042

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   NILLAQGKI 9
           N+L+ +GK+
Sbjct: 767 NVLICEGKL 775
>XP_006714210
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 716 NLLAAQGSI 724
>XP_006714209
          Length = 936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>XP_005262911
          Length = 1067

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 716 NLLAAQGSI 724
>XP_005262909
          Length = 1166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 716 NLLAAQGSI 724
>XP_005262908
          Length = 1194

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 716 NLLAAQGSI 724
>XP_005262907
          Length = 1205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>XP_006714208
          Length = 1207

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 729 NLLAAQGSI 737
>XP_005262906
          Length = 1218

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>XP_006714207
          Length = 1220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 742 NLLAAQGSI 750
>XP_006714206
          Length = 1233

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>XP_006714205
          Length = 1233

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>XP_006714204
          Length = 1233

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>XP_005262904
          Length = 1233

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG I
Sbjct: 755 NLLAAQGSI 763
>XP_005265799
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           NILL  G+I
Sbjct: 794 NILLTHGRI 802
>XP_005265798
          Length = 976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           NILL  G+I
Sbjct: 797 NILLTHGRI 805
>XP_005265797
          Length = 977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           NILL  G+I
Sbjct: 798 NILLTHGRI 806
>NP_001177130
          Length = 463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 235 VLLTQGKV 242
>NP_065681
          Length = 1072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NILLAQGK 8
           NIL+A+G+
Sbjct: 879 NILVAEGR 886
>NP_066124
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NILLAQGK 8
           NIL+A+G+
Sbjct: 879 NILVAEGR 886
>NP_056505
          Length = 1315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NILLAQG 7
           NILLA+G
Sbjct: 130 NILLAKG 136
>NP_001230242
          Length = 1294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NILLAQG 7
           NILLA+G
Sbjct: 130 NILLAKG 136
>NP_001191375
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLAQGKI 9
           N+LLA+G +
Sbjct: 131 NLLLAEGTL 139
>NP_060817
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLAQGKI 9
           N+LLA+G +
Sbjct: 131 NLLLAEGTL 139
>XP_006717999
          Length = 1207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NILLAQGK 8
           NIL+A+G+
Sbjct: 972 NILVAEGR 979
>XP_006717822
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>XP_006717821
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>XP_005269749
          Length = 901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>XP_006717820
          Length = 949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>XP_006712484
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NILLAQG 7
           NILLA+G
Sbjct: 130 NILLAKG 136
>XP_006712483
          Length = 1306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NILLAQG 7
           NILLA+G
Sbjct: 130 NILLAKG 136
>XP_005246521
          Length = 1315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   NILLAQG 7
           NILLA+G
Sbjct: 130 NILLAKG 136
>NP_001191376
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NILLAQGKI 9
           N+LLA+G +
Sbjct: 131 NLLLAEGTL 139
>NP_065081
          Length = 951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILLAQGKI 9
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>NP_005498
          Length = 166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  NILLAQGK 8
          NI+L +GK
Sbjct: 46 NIILEEGK 53
>NP_001276976
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLAQGK 8
           LLAQGK
Sbjct: 384 LLAQGK 389
>NP_001276975
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLAQGK 8
           LLAQGK
Sbjct: 221 LLAQGK 226
>NP_004110
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L+  GK+
Sbjct: 816 NVLVTHGKV 824
>NP_056305
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NILLAQGKI 9
           N+L AQG +
Sbjct: 749 NLLAAQGSL 757
>NP_001155238
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLAQGKI 9
           ILLA+G++
Sbjct: 309 ILLAEGRL 316
>NP_689837
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NILLAQG 7
           N+LL QG
Sbjct: 111 NVLLVQG 117
>NP_001229306
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NILLAQG 7
           N+LL QG
Sbjct: 111 NVLLVQG 117
>NP_067646
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLAQGKI 9
           ILL+QG++
Sbjct: 172 ILLSQGEV 179
>NP_000678
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLAQGKI 9
           ILLA+G++
Sbjct: 337 ILLAEGRL 344
>NP_775871
          Length = 8384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NILLAQGKI 9
            NI+L  GK+
Sbjct: 1342 NIVLQDGKV 1350
>XP_006724141
          Length = 1426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LLAQGK 8
           LLAQGK
Sbjct: 346 LLAQGK 351
>XP_005260374
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLAQGKI 9
           ILLA+G++
Sbjct: 309 ILLAEGRL 316
>XP_005260373
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLAQGKI 9
           ILLA+G++
Sbjct: 309 ILLAEGRL 316
>XP_005271971
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NILLAQG 7
           N+LL QG
Sbjct: 111 NVLLVQG 117
>XP_006711542
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLAQGKI 9
           ILL+QG++
Sbjct: 210 ILLSQGEV 217
>XP_006711541
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLAQGKI 9
           ILL+QG++
Sbjct: 210 ILLSQGEV 217
>XP_005245460
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLAQGKI 9
           ILL+QG++
Sbjct: 210 ILLSQGEV 217
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.146    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 449,252
Number of extensions: 642
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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