Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     390
XP_005267290                                                           20     390
NP_055544                                                              17    3301
NP_036257                                                              16    5631
NP_078858                                                              16    5631
NP_001278232                                                           16    5631
NP_001278214                                                           16    5631
NP_689964                                                              16    5631
NP_443109                                                              16    5631
NP_722576                                                              16    5631
NP_963836                                                              16    5631
XP_005262424                                                           16    5631
XP_005254198                                                           16    5631
XP_005252459                                                           16    5631
XP_006717485                                                           16    5631
XP_006717472                                                           16    5631
XP_006717471                                                           16    5631
NP_001139669                                                           16    5631
NP_003473                                                              16    7355
XP_006719679                                                           16    7355
XP_005269219                                                           16    7355
XP_006719678                                                           16    7355
XP_006719677                                                           16    7355
NP_733468                                                              15    9605
NP_003757                                                              15    9605
NP_653091                                                              15    9605
NP_001139283                                                           15    9605
NP_849180                                                              15    9605
NP_005522                                                              15    9605
NP_006600                                                              15    9605
NP_001193496                                                           15    9605
NP_201583                                                              15    9605
NP_001274111                                                           15    9605
NP_001025174                                                           15    9605
NP_059978                                                              15    9605
NP_001139291                                                           15    9605
NP_001072983                                                           15    9605
NP_006198                                                              15    9605
NP_001274731                                                           15    9605
NP_003184                                                              15    9605
NP_001274730                                                           15    9605
XP_005260507                                                           15    9605
XP_006723885                                                           15    9605
XP_005257817                                                           15    9605
XP_005257816                                                           15    9605
XP_005257815                                                           15    9605
XP_006711353                                                           15    9605
XP_005245184                                                           15    9605
NP_955459                                                              15    9605
>NP_005091
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  NGQLSTIN 8
          NGQLSTIN
Sbjct: 59 NGQLSTIN 66
>XP_005267290
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  NGQLSTIN 8
          NGQLSTIN
Sbjct: 59 NGQLSTIN 66
>NP_055544
          Length = 526

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NGQLSTIN 8
           +GQL+TIN
Sbjct: 176 HGQLTTIN 183
>NP_036257
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  NGQLSTINS 9
          N QL T+N+
Sbjct: 58 NSQLKTVNN 66
>NP_078858
          Length = 4981

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NGQLSTINS 9
           +G+LSTI+S
Sbjct: 638 SGRLSTISS 646
>NP_001278232
          Length = 4983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NGQLSTINS 9
           +G+LSTI+S
Sbjct: 638 SGRLSTISS 646
>NP_001278214
          Length = 4982

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   NGQLSTINS 9
           +G+LSTI+S
Sbjct: 638 SGRLSTISS 646
>NP_689964
          Length = 468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           NG+L  +NS
Sbjct: 97  NGELPVVNS 105
>NP_443109
          Length = 301

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  NGQLSTIN 8
          +GQL+T+N
Sbjct: 53 SGQLNTLN 60
>NP_722576
          Length = 3080

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    NGQLSTINS 9
            N  LST+NS
Sbjct: 1723 NRSLSTVNS 1731
>NP_963836
          Length = 268

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  NGQLSTIN 8
          +GQL+T+N
Sbjct: 53 SGQLNTLN 60
>XP_005262424
          Length = 2875

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    NGQLSTINS 9
            N  LST+NS
Sbjct: 1518 NRSLSTVNS 1526
>XP_005254198
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  NGQLSTINS 9
          N QL T+N+
Sbjct: 58 NSQLKTVNN 66
>XP_005252459
          Length = 520

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           NG+L  +NS
Sbjct: 149 NGELPVVNS 157
>XP_006717485
          Length = 383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           NG+L  +NS
Sbjct: 97  NGELPVVNS 105
>XP_006717472
          Length = 434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           NG+L  +NS
Sbjct: 149 NGELPVVNS 157
>XP_006717471
          Length = 435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           NG+L  +NS
Sbjct: 149 NGELPVVNS 157
>NP_001139669
          Length = 7081

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    NGQLSTINS 9
            NG + T+NS
Sbjct: 1888 NGTICTVNS 1896
>NP_003473
          Length = 5537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GQLSTIN 8
            GQLSTI+
Sbjct: 2013 GQLSTIS 2019
>XP_006719679
          Length = 5536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GQLSTIN 8
            GQLSTI+
Sbjct: 2012 GQLSTIS 2018
>XP_005269219
          Length = 5537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GQLSTIN 8
            GQLSTI+
Sbjct: 2013 GQLSTIS 2019
>XP_006719678
          Length = 5539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GQLSTIN 8
            GQLSTI+
Sbjct: 2015 GQLSTIS 2021
>XP_006719677
          Length = 5540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    GQLSTIN 8
            GQLSTI+
Sbjct: 2016 GQLSTIS 2022
>NP_733468
          Length = 2342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GQLSTIN 8
           GQL+T+N
Sbjct: 818 GQLTTMN 824
>NP_003757
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           +GQ  TIN+
Sbjct: 279 SGQFGTINN 287
>NP_653091
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GQLSTIN 8
           GQL+T+N
Sbjct: 792 GQLTTMN 798
>NP_001139283
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NGQLSTINS 9
           +G+LS+IN+
Sbjct: 496 DGKLSSINN 504
>NP_849180
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NGQLST 6
           NGQ+ST
Sbjct: 414 NGQMST 419
>NP_005522
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NGQLSTIN 8
           +G+L+TIN
Sbjct: 663 HGRLTTIN 670
>NP_006600
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           NG  ++INS
Sbjct: 180 NGSFTSINS 188
>NP_001193496
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NGQLSTIN 8
           +G+L+TIN
Sbjct: 663 HGRLTTIN 670
>NP_201583
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NGQLSTINS 9
           +G+LS+IN+
Sbjct: 523 DGKLSSINN 531
>NP_001274111
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NGQLST 6
           NGQ+ST
Sbjct: 389 NGQMST 394
>NP_001025174
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NGQLST 6
           NGQ+ST
Sbjct: 392 NGQMST 397
>NP_059978
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NGQLSTINS 9
           +G+LS+IN+
Sbjct: 499 DGKLSSINN 507
>NP_001139291
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   NGQLSTINS 9
           +G+LS+IN+
Sbjct: 536 DGKLSSINN 544
>NP_001072983
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GQLSTIN 8
           GQL T+N
Sbjct: 363 GQLKTLN 369
>NP_006198
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GQLSTINS 9
           GQL+ +NS
Sbjct: 126 GQLTLVNS 133
>NP_001274731
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GQLSTIN 8
           GQL T+N
Sbjct: 250 GQLKTLN 256
>NP_003184
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GQLSTIN 8
           GQL T+N
Sbjct: 363 GQLKTLN 369
>NP_001274730
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GQLSTIN 8
           GQL T+N
Sbjct: 414 GQLKTLN 420
>XP_005260507
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NGQLSTINS 9
           +GQLST+ S
Sbjct: 404 SGQLSTLVS 412
>XP_006723885
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NGQLSTINS 9
           +GQLST+ S
Sbjct: 426 SGQLSTLVS 434
>XP_005257817
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           +GQ  TIN+
Sbjct: 279 SGQFGTINN 287
>XP_005257816
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           +GQ  TIN+
Sbjct: 279 SGQFGTINN 287
>XP_005257815
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NGQLSTINS 9
           +GQ  TIN+
Sbjct: 279 SGQFGTINN 287
>XP_006711353
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NGQLSTIN 8
           +G+L+TIN
Sbjct: 611 HGRLTTIN 618
>XP_005245184
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NGQLSTIN 8
           +G+L+TIN
Sbjct: 723 HGRLTTIN 730
>NP_955459
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NGQLSTINS 9
           +GQLST+ S
Sbjct: 623 SGQLSTLVS 631
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.114    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 416,708
Number of extensions: 639
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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