Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              20     390
NP_001032903                                                           17    3301
NP_001229808                                                           16    5631
NP_001229807                                                           16    5631
NP_001229805                                                           16    5631
NP_113637                                                              16    5631
NP_714921                                                              16    5631
NP_064501                                                              16    5631
NP_001121899                                                           16    5631
NP_001121900                                                           16    5631
NP_001229806                                                           16    5631
NP_001229804                                                           16    5631
NP_060725                                                              16    5631
XP_005249931                                                           16    5631
XP_005249930                                                           16    5631
XP_005249929                                                           16    5631
XP_005249928                                                           16    5631
XP_005249927                                                           16    5631
XP_005249926                                                           16    5631
XP_005249925                                                           16    5631
XP_006715850                                                           16    5631
XP_005249924                                                           16    5631
XP_005249923                                                           16    5631
NP_001099039                                                           16    5631
NP_777589                                                              16    5631
NP_004805                                                              16    7355
NP_001157887                                                           16    7355
NP_057237                                                              16    7355
NP_001274170                                                           16    7355
NP_001012534                                                           16    7355
NP_001012532                                                           16    7355
NP_112188                                                              16    7355
NP_001017420                                                           15    9605
NP_872325                                                              15    9605
NP_001138363                                                           15    9605
NP_057670                                                              15    9605
NP_851825                                                              15    9605
NP_001135906                                                           15    9605
NP_001229347                                                           15    9605
NP_001229346                                                           15    9605
NP_001229345                                                           15    9605
NP_037460                                                              15    9605
NP_036347                                                              15    9605
NP_004934                                                              15    9605
NP_003892                                                              15    9605
NP_945344                                                              15    9605
NP_775834                                                              15    9605
NP_653175                                                              15    9605
NP_851808                                                              15    9605
XP_005256892                                                           15    9605
XP_005256891                                                           15    9605
XP_005256890                                                           15    9605
XP_006720374                                                           15    9605
XP_006720373                                                           15    9605
XP_006720372                                                           15    9605
XP_006720371                                                           15    9605
XP_006720370                                                           15    9605
XP_006720369                                                           15    9605
XP_005267813                                                           15    9605
XP_005267812                                                           15    9605
XP_005267811                                                           15    9605
XP_006718116                                                           15    9605
XP_006718115                                                           15    9605
XP_005270320                                                           15    9605
XP_006716360                                                           15    9605
XP_006715090                                                           15    9605
XP_006715089                                                           15    9605
XP_006715088                                                           15    9605
XP_005249008                                                           15    9605
>NP_005350
          Length = 552

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   NELAFQPAI 9
           NELAFQP I
Sbjct: 306 NELAFQPPI 314
>NP_001032903
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   NELAFQPAI 9
           NEL+F+P +
Sbjct: 444 NELSFKPPV 452
>NP_001229808
          Length = 756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELAFQPAI 9
           ++AFQP+I
Sbjct: 464 QVAFQPSI 471
>NP_001229807
          Length = 756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELAFQPAI 9
           ++AFQP+I
Sbjct: 464 QVAFQPSI 471
>NP_001229805
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELAFQPAI 9
           ++AFQP+I
Sbjct: 529 QVAFQPSI 536
>NP_113637
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 858 ELAFSPA 864
>NP_714921
          Length = 680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NELAFQPAI 9
           NEL+FQ  I
Sbjct: 111 NELSFQEVI 119
>NP_064501
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NELAFQPA 8
           ++LAFQP+
Sbjct: 740 SDLAFQPS 747
>NP_001121899
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NELAFQPA 8
           ++LAFQP+
Sbjct: 739 SDLAFQPS 746
>NP_001121900
          Length = 837

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   NELAFQPA 8
           ++LAFQP+
Sbjct: 730 SDLAFQPS 737
>NP_001229806
          Length = 800

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELAFQPAI 9
           ++AFQP+I
Sbjct: 508 QVAFQPSI 515
>NP_001229804
          Length = 891

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELAFQPAI 9
           ++AFQP+I
Sbjct: 599 QVAFQPSI 606
>NP_060725
          Length = 826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELAFQPAI 9
           ++AFQP+I
Sbjct: 534 QVAFQPSI 541
>XP_005249931
          Length = 862

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 800 ELAFSPA 806
>XP_005249930
          Length = 888

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 826 ELAFSPA 832
>XP_005249929
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 832 ELAFSPA 838
>XP_005249928
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 835 ELAFSPA 841
>XP_005249927
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 841 ELAFSPA 847
>XP_005249926
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 858 ELAFSPA 864
>XP_005249925
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 867 ELAFSPA 873
>XP_006715850
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 867 ELAFSPA 873
>XP_005249924
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 867 ELAFSPA 873
>XP_005249923
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 867 ELAFSPA 873
>NP_001099039
          Length = 193

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   NELAFQP 7
           N LAFQP
Sbjct: 96  NMLAFQP 102
>NP_777589
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ELAFQPA 8
           ELAF PA
Sbjct: 832 ELAFSPA 838
>NP_004805
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NELAFQP 7
           NE+AF P
Sbjct: 331 NEVAFHP 337
>NP_001157887
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  ELAFQP 7
          E+AFQP
Sbjct: 65 EIAFQP 70
>NP_057237
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  ELAFQP 7
          E+AFQP
Sbjct: 65 EIAFQP 70
>NP_001274170
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  ELAFQPAI 9
          +++FQPA+
Sbjct: 3  KISFQPAV 10
>NP_001012534
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  ELAFQPAI 9
          +++FQPA+
Sbjct: 3  KISFQPAV 10
>NP_001012532
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  ELAFQPAI 9
          +++FQPA+
Sbjct: 3  KISFQPAV 10
>NP_112188
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  ELAFQPAI 9
          +++FQPA+
Sbjct: 3  KISFQPAV 10
>NP_001017420
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NELAFQPAI 9
           NEL FQ  +
Sbjct: 461 NELGFQQVV 469
>NP_872325
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELAFQPAI 9
           +LAF PA+
Sbjct: 573 DLAFMPAM 580
>NP_001138363
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AFQPAI 9
          AFQPA+
Sbjct: 65 AFQPAL 70
>NP_057670
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AFQPAI 9
          AFQPA+
Sbjct: 65 AFQPAL 70
>NP_851825
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 163 NEFAFSP 169
>NP_001135906
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NELAFQP 7
           N+L FQP
Sbjct: 646 NDLFFQP 652
>NP_001229347
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 236 NEFAFSP 242
>NP_001229346
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 255 NEFAFSP 261
>NP_001229345
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 163 NEFAFSP 169
>NP_037460
          Length = 320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LAFQPA 8
           +AFQPA
Sbjct: 109 MAFQPA 114
>NP_036347
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NELAFQP 7
           N+L FQP
Sbjct: 699 NDLFFQP 705
>NP_004934
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 288 NEFAFSP 294
>NP_003892
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NELAFQPAI 9
           N+L F P+I
Sbjct: 475 NQLQFPPSI 483
>NP_945344
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   NELAFQP 7
           N+LA QP
Sbjct: 309 NDLALQP 315
>NP_775834
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELAFQPAI 9
           EL+F+P I
Sbjct: 413 ELSFKPTI 420
>NP_653175
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 224 NEFAFSP 230
>NP_851808
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 224 NEFAFSP 230
>XP_005256892
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  LAFQPAI 9
          L FQPA+
Sbjct: 18 LGFQPAL 24
>XP_005256891
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  LAFQPAI 9
          L FQPA+
Sbjct: 18 LGFQPAL 24
>XP_005256890
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  LAFQPAI 9
          L FQPA+
Sbjct: 18 LGFQPAL 24
>XP_006720374
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1  NELAFQP 7
          NE AF P
Sbjct: 51 NEFAFSP 57
>XP_006720373
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1  NELAFQP 7
          NE AF P
Sbjct: 51 NEFAFSP 57
>XP_006720372
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1  NELAFQP 7
          NE AF P
Sbjct: 51 NEFAFSP 57
>XP_006720371
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 163 NEFAFSP 169
>XP_006720370
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 224 NEFAFSP 230
>XP_006720369
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1   NELAFQP 7
           NE AF P
Sbjct: 224 NEFAFSP 230
>XP_005267813
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AFQPAI 9
          AFQPA+
Sbjct: 65 AFQPAL 70
>XP_005267812
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AFQPAI 9
          AFQPA+
Sbjct: 65 AFQPAL 70
>XP_005267811
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AFQPAI 9
          AFQPA+
Sbjct: 65 AFQPAL 70
>XP_006718116
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NELAFQPAI 9
           N+L F P+I
Sbjct: 395 NQLQFPPSI 403
>XP_006718115
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NELAFQPAI 9
           N+L F P+I
Sbjct: 474 NQLQFPPSI 482
>XP_005270320
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NELAFQPAI 9
           N+L F P+I
Sbjct: 475 NQLQFPPSI 483
>XP_006716360
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   NELAFQPAI 9
           NEL FQ  +
Sbjct: 461 NELGFQQVV 469
>XP_006715090
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELAFQPAI 9
           EL+F+P I
Sbjct: 257 ELSFKPTI 264
>XP_006715089
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELAFQPAI 9
           EL+F+P I
Sbjct: 350 ELSFKPTI 357
>XP_006715088
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELAFQPAI 9
           EL+F+P I
Sbjct: 350 ELSFKPTI 357
>XP_005249008
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELAFQPAI 9
           EL+F+P I
Sbjct: 404 ELSFKPTI 411
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.135    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 597,521
Number of extensions: 738
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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