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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              20     390
XP_006716142                                                           20     390
XP_005250088                                                           20     390
XP_006716141                                                           20     390
XP_005250085                                                           20     390
XP_006716140                                                           20     390
XP_005250084                                                           20     390
XP_005250083                                                           20     390
XP_005250082                                                           20     390
NP_065789                                                              16    5631
NP_001073932                                                           15    9605
NP_001368                                                              15    9605
NP_116753                                                              15    9605
NP_840060                                                              15    9605
NP_116754                                                              15    9605
NP_001167543                                                           15    9605
NP_001265548                                                           15    9605
NP_001167542                                                           15    9605
NP_116755                                                              15    9605
NP_116749                                                              15    9605
NP_001161834                                                           15    9605
NP_001161832                                                           15    9605
NP_116750                                                              15    9605
NP_001161833                                                           15    9605
NP_116751                                                              15    9605
NP_001161835                                                           15    9605
NP_055337                                                              15    9605
NP_066278                                                              15    9605
NP_001258662                                                           15    9605
XP_006718966                                                           15    9605
XP_006715638                                                           15    9605
XP_005267216                                                           15    9605
XP_005248535                                                           15    9605
XP_006713231                                                           15    9605
XP_006713229                                                           15    9605
NP_659490                                                              15    9605
NP_115521                                                              15    9605

>NP_733751
          Length = 4911

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1626 NDTMSNAQR 1634



>XP_006716142
          Length = 4927

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1643 NDTMSNAQR 1651



>XP_005250088
          Length = 4928

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1643 NDTMSNAQR 1651



>XP_006716141
          Length = 4959

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1643 NDTMSNAQR 1651



>XP_005250085
          Length = 4979

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1643 NDTMSNAQR 1651



>XP_006716140
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1643 NDTMSNAQR 1651



>XP_005250084
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1643 NDTMSNAQR 1651



>XP_005250083
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1642 NDTMSNAQR 1650



>XP_005250082
          Length = 4983

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NDTMLNAQR 9
            NDTM NAQR
Sbjct: 1643 NDTMSNAQR 1651



>NP_065789
          Length = 1771

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DTMLNAQR 9
           D++LN+QR
Sbjct: 716 DSLLNSQR 723



>NP_001073932
          Length = 4314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    DTMLNAQR 9
            DT LNA R
Sbjct: 4184 DTFLNALR 4191



>NP_001368
          Length = 4307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    DTMLNAQR 9
            DT LNA R
Sbjct: 4177 DTFLNALR 4184



>NP_116753
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 724 NDTGMNAE 731



>NP_840060
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DTMLNAQR 9
           DT LNA R
Sbjct: 148 DTFLNAWR 155



>NP_116754
          Length = 1048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 735 NDTGMNAE 742



>NP_001167543
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DTMLNAQR 9
           DT LNA R
Sbjct: 148 DTFLNAWR 155



>NP_001265548
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 724 NDTGMNAE 731



>NP_001167542
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DTMLNAQR 9
           DT LNA R
Sbjct: 148 DTFLNAWR 155



>NP_116755
          Length = 1340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 735 NDTGMNAE 742



>NP_116749
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 703 NDTGMNAE 710



>NP_001161834
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 703 NDTGMNAE 710



>NP_001161832
          Length = 1339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 703 NDTGMNAE 710



>NP_116750
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 703 NDTGMNAE 710



>NP_001161833
          Length = 1065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 703 NDTGMNAE 710



>NP_116751
          Length = 1337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 703 NDTGMNAE 710



>NP_001161835
          Length = 1329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 703 NDTGMNAE 710



>NP_055337
          Length = 1021

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   NDTMLNAQ 8
           NDT +NA+
Sbjct: 703 NDTGMNAE 710



>NP_066278
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NDTMLN 6
           NDT+LN
Sbjct: 629 NDTVLN 634



>NP_001258662
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NDTMLN 6
           NDT+LN
Sbjct: 593 NDTVLN 598



>XP_006718966
          Length = 4300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    DTMLNAQR 9
            DT LNA R
Sbjct: 4170 DTFLNALR 4177



>XP_006715638
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NDTMLNAQ 8
           NDT  NAQ
Sbjct: 253 NDTNQNAQ 260



>XP_005267216
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NDTMLNAQ 8
           NDT  NAQ
Sbjct: 253 NDTNQNAQ 260



>XP_005248535
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  DTMLNAQR 9
          DT LNA R
Sbjct: 77 DTFLNAWR 84



>XP_006713231
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NDTMLN 6
           NDT+LN
Sbjct: 529 NDTVLN 534



>XP_006713229
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   NDTMLN 6
           NDT+LN
Sbjct: 584 NDTVLN 589



>NP_659490
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   NDTMLNAQR 9
           ND MLN+ +
Sbjct: 278 NDQMLNSMQ 286



>NP_115521
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   NDTMLNAQ 8
           NDT  NAQ
Sbjct: 253 NDTNQNAQ 260



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.119    0.313 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 394,888
Number of extensions: 632
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)