Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_056106                                                              17    4312
NP_789786                                                              17    4312
XP_005276826                                                           17    4312
XP_005276825                                                           17    4312
XP_005276824                                                           17    4312
XP_005276823                                                           17    4312
XP_005276822                                                           17    4312
XP_006726278                                                           17    4312
XP_005276821                                                           17    4312
XP_006726277                                                           17    4312
XP_005276820                                                           17    4312
XP_005276819                                                           17    4312
XP_005276818                                                           17    4312
XP_005248522                                                           17    4312
XP_005248521                                                           17    4312
XP_005248520                                                           17    4312
XP_005248519                                                           17    4312
XP_005248518                                                           17    4312
XP_006714633                                                           17    4312
XP_005248517                                                           17    4312
XP_006714632                                                           17    4312
XP_005248516                                                           17    4312
XP_005248515                                                           17    4312
XP_005248514                                                           17    4312
XP_005270509                                                           17    4312
XP_005270508                                                           17    4312
NP_001278383                                                           16    5631
NP_055676                                                              16    5631
NP_001273456                                                           16    5631
NP_055140                                                              16    5631
NP_001098707                                                           16    5631
NP_001263400                                                           16    5631
NP_005724                                                              16    5631
XP_006721418                                                           16    5631
XP_006714577                                                           16    5631
NP_598397                                                              16    7355
NP_004728                                                              16    7355
NP_997639                                                              16    7355
NP_002017                                                              16    7355
NP_997643                                                              16    7355
NP_997647                                                              16    7355
NP_997641                                                              16    7355
XP_006724438                                                           16    7355
XP_005261889                                                           16    7355
XP_005261888                                                           16    7355
XP_005246474                                                           16    7355
XP_005246473                                                           16    7355
XP_005246472                                                           16    7355
XP_005246471                                                           16    7355
XP_005246470                                                           16    7355
XP_005246469                                                           16    7355
XP_005246468                                                           16    7355
XP_005246467                                                           16    7355
XP_005246466                                                           16    7355
XP_005246465                                                           16    7355
XP_005246464                                                           16    7355
XP_005246463                                                           16    7355
XP_005246462                                                           16    7355
XP_005246461                                                           16    7355
XP_005246460                                                           16    7355
XP_005246459                                                           16    7355
XP_005246458                                                           16    7355
XP_005246457                                                           16    7355
XP_005246456                                                           16    7355
XP_005246455                                                           16    7355
XP_005246454                                                           16    7355
NP_620636                                                              15    9605
NP_006827                                                              15    9605
NP_443179                                                              15    9605
NP_003062                                                              15    9605
XP_005247781                                                           15    9605
>NP_056106
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAVV++NL
Sbjct: 231 NAVVRENL 238
>NP_789786
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005276826
          Length = 348

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 210 NAVLKENL 217
>XP_005276825
          Length = 349

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005276824
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  NAVVKKNL 8
          NAV+K+NL
Sbjct: 86 NAVLKENL 93
>XP_005276823
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  NAVVKKNL 8
          NAV+K+NL
Sbjct: 86 NAVLKENL 93
>XP_005276822
          Length = 421

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 121 NAVLKENL 128
>XP_006726278
          Length = 434

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 134 NAVLKENL 141
>XP_005276821
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 138 NAVLKENL 145
>XP_006726277
          Length = 506

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005276820
          Length = 510

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 210 NAVLKENL 217
>XP_005276819
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005276818
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005248522
          Length = 348

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 210 NAVLKENL 217
>XP_005248521
          Length = 349

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005248520
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  NAVVKKNL 8
          NAV+K+NL
Sbjct: 86 NAVLKENL 93
>XP_005248519
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  NAVVKKNL 8
          NAV+K+NL
Sbjct: 86 NAVLKENL 93
>XP_005248518
          Length = 421

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 121 NAVLKENL 128
>XP_006714633
          Length = 434

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 134 NAVLKENL 141
>XP_005248517
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 138 NAVLKENL 145
>XP_006714632
          Length = 506

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005248516
          Length = 510

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 210 NAVLKENL 217
>XP_005248515
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005248514
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   NAVVKKNL 8
           NAV+K+NL
Sbjct: 211 NAVLKENL 218
>XP_005270509
          Length = 349

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VVKKNLL 9
           +VKKNLL
Sbjct: 341 IVKKNLL 347
>XP_005270508
          Length = 430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VVKKNLL 9
           +VKKNLL
Sbjct: 422 IVKKNLL 428
>NP_001278383
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV++KN
Sbjct: 293 NAVIRKN 299
>NP_055676
          Length = 946

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV++KN
Sbjct: 444 NAVIRKN 450
>NP_001273456
          Length = 975

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV++KN
Sbjct: 444 NAVIRKN 450
>NP_055140
          Length = 474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VVKKNLL 9
           VVKKN+L
Sbjct: 404 VVKKNIL 410
>NP_001098707
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VVKKNLL 9
           VVKKN+L
Sbjct: 457 VVKKNIL 463
>NP_001263400
          Length = 474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VVKKNLL 9
           VVKKN+L
Sbjct: 404 VVKKNIL 410
>NP_005724
          Length = 890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  AVVKKNLL 9
          +VV+KNLL
Sbjct: 33 SVVRKNLL 40
>XP_006721418
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV++KN
Sbjct: 444 NAVIRKN 450
>XP_006714577
          Length = 890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  AVVKKNLL 9
          +VV+KNLL
Sbjct: 33 SVVRKNLL 40
>NP_598397
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV+K+N
Sbjct: 339 NAVIKQN 345
>NP_004728
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV+K+N
Sbjct: 339 NAVIKQN 345
>NP_997639
          Length = 2176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>NP_002017
          Length = 2355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>NP_997643
          Length = 2330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>NP_997647
          Length = 2477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>NP_997641
          Length = 2296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_006724438
          Length = 577

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV+K+N
Sbjct: 339 NAVIKQN 345
>XP_005261889
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV+K+N
Sbjct: 339 NAVIKQN 345
>XP_005261888
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   NAVVKKN 7
           NAV+K+N
Sbjct: 339 NAVIKQN 345
>XP_005246474
          Length = 2240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_005246473
          Length = 2246

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_005246472
          Length = 2265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_005246471
          Length = 2266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_005246470
          Length = 2267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246469
          Length = 2271

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_005246468
          Length = 2273

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246467
          Length = 2337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246466
          Length = 2361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_005246465
          Length = 2362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246464
          Length = 2363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246463
          Length = 2386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_005246462
          Length = 2387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246461
          Length = 2392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1321 NAVVLTNLL 1329
>XP_005246460
          Length = 2393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246459
          Length = 2421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246458
          Length = 2427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246457
          Length = 2446

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246456
          Length = 2452

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246455
          Length = 2458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>XP_005246454
          Length = 2483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    NAVVKKNLL 9
            NAVV  NLL
Sbjct: 1412 NAVVLTNLL 1420
>NP_620636
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VKKNLL 9
           VKKNLL
Sbjct: 323 VKKNLL 328
>NP_006827
          Length = 2671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    NAVVKKNLL 9
            +AV++KN++
Sbjct: 2420 DAVIRKNIV 2428
>NP_443179
          Length = 2170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   NAVVKKNLL 9
           NAV ++NLL
Sbjct: 341 NAVWQRNLL 349
>NP_003062
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VKKNLL 9
           VKKNLL
Sbjct: 323 VKKNLL 328
>XP_005247781
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VKKNLL 9
           VKKNLL
Sbjct: 323 VKKNLL 328
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.129    0.315 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,803
Number of extensions: 454
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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