Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           19     665
NP_858045                                                              19     665
NP_006525                                                              19     665
NP_001167559                                                           19     665
NP_060119                                                              16    5631
NP_951058                                                              16    5631
NP_940978                                                              15    9605
NP_001275882                                                           15    9605
NP_065191                                                              15    9605
NP_001275884                                                           15    9605
NP_001275880                                                           15    9605
NP_079019                                                              15    9605
NP_066962                                                              15    9605
NP_001099147                                                           15    9605
XP_006725063                                                           15    9605
XP_006714368                                                           15    9605
XP_005265758                                                           15    9605
XP_005264496                                                           15    9605
XP_006710698                                                           15    9605
XP_005244806                                                           15    9605
XP_006710697                                                           15    9605
XP_006710696                                                           15    9605
NP_001239204                                                           15    9605
NP_001239203                                                           15    9605
NP_006789                                                              15    9605
>NP_001167558
          Length = 1423

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NAMMLSRMG 9
            NAMM SRMG
Sbjct: 1332 NAMMSSRMG 1340
>NP_858045
          Length = 1424

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NAMMLSRMG 9
            NAMM SRMG
Sbjct: 1333 NAMMSSRMG 1341
>NP_006525
          Length = 1420

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NAMMLSRMG 9
            NAMM SRMG
Sbjct: 1329 NAMMSSRMG 1337
>NP_001167559
          Length = 1415

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    NAMMLSRMG 9
            NAMM SRMG
Sbjct: 1324 NAMMSSRMG 1332
>NP_060119
          Length = 875

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NA+M SRM
Sbjct: 814 NALMASRM 821
>NP_951058
          Length = 853

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NA+M SRM
Sbjct: 792 NALMASRM 799
>NP_940978
          Length = 2045

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NAMMLSRMG 9
           NA+ LSR G
Sbjct: 402 NAVCLSRRG 410
>NP_001275882
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MMLSRMG 9
           +MLSR+G
Sbjct: 753 LMLSRLG 759
>NP_065191
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MMLSRMG 9
           +MLSR+G
Sbjct: 787 LMLSRLG 793
>NP_001275884
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MMLSRMG 9
           +MLSR+G
Sbjct: 433 LMLSRLG 439
>NP_001275880
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MMLSRMG 9
           +MLSR+G
Sbjct: 811 LMLSRLG 817
>NP_079019
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 439 NAMRLSRI 446
>NP_066962
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 441 NAMKLSRI 448
>NP_001099147
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 448 NAMRLSRI 455
>XP_006725063
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 201 NAMRLSRI 208
>XP_006714368
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 201 NAMRLSRI 208
>XP_005265758
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 215 NAMKLSRI 222
>XP_005264496
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MMLSRMG 9
           +MLSR+G
Sbjct: 668 LMLSRLG 674
>XP_006710698
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NAMMLSRMG 9
           NA+ LSR G
Sbjct: 402 NAVCLSRRG 410
>XP_005244806
          Length = 2049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NAMMLSRMG 9
           NA+ LSR G
Sbjct: 402 NAVCLSRRG 410
>XP_006710697
          Length = 2053

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NAMMLSRMG 9
           NA+ LSR G
Sbjct: 402 NAVCLSRRG 410
>XP_006710696
          Length = 2057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   NAMMLSRMG 9
           NA+ LSR G
Sbjct: 402 NAVCLSRRG 410
>NP_001239204
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 439 NAMRLSRI 446
>NP_001239203
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 605 NAMRLSRI 612
>NP_006789
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   NAMMLSRM 8
           NAM LSR+
Sbjct: 439 NAMRLSRI 446
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.126    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 206,018
Number of extensions: 143
Number of successful extensions: 25
Number of sequences better than 10000.0: 25
Number of HSP's gapped: 25
Number of HSP's successfully gapped: 25
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package