Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              19     665
XP_006715292                                                           19     665
NP_775771                                                              19     869
NP_660204                                                              19     869
XP_006720466                                                           19     869
XP_005254230                                                           19     869
XP_006720465                                                           19     869
XP_005254228                                                           19     869
NP_001020276                                                           17    2528
NP_001258671                                                           17    2528
NP_001258670                                                           17    2528
NP_001883                                                              17    2528
NP_001885                                                              16    7355
NP_689407                                                              16    7355
NP_001276841                                                           16    7355
NP_001884                                                              16    7355
NP_620693                                                              16    7355
XP_005256394                                                           16    7355
XP_005256393                                                           16    7355
NP_001188358                                                           15    9605
NP_036427                                                              15    9605
NP_001186210                                                           15    9605
XP_006724247                                                           15    9605
XP_006724246                                                           15    9605
XP_006724245                                                           15    9605
XP_006724244                                                           15    9605
XP_006724243                                                           15    9605
XP_005261477                                                           15    9605
XP_005261476                                                           15    9605
XP_005261474                                                           15    9605
XP_006724242                                                           15    9605
XP_005261473                                                           15    9605
XP_005261472                                                           15    9605
>NP_115927
          Length = 1321

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRYASVNA 9
           VRYASVNA
Sbjct: 203 VRYASVNA 210
>XP_006715292
          Length = 759

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VRYASVNA 9
           VRYASVNA
Sbjct: 190 VRYASVNA 197
>NP_775771
          Length = 1244

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VRYASVNA 9
           VRYAS+NA
Sbjct: 190 VRYASINA 197
>NP_660204
          Length = 337

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VRYASVNA 9
           VRYAS+NA
Sbjct: 185 VRYASINA 192
>XP_006720466
          Length = 1175

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VRYASVNA 9
           VRYAS+NA
Sbjct: 121 VRYASINA 128
>XP_005254230
          Length = 1175

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VRYASVNA 9
           VRYAS+NA
Sbjct: 121 VRYASINA 128
>XP_006720465
          Length = 1239

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VRYASVNA 9
           VRYAS+NA
Sbjct: 185 VRYASINA 192
>XP_005254228
          Length = 1250

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VRYASVNA 9
           VRYAS+NA
Sbjct: 196 VRYASINA 203
>NP_001020276
          Length = 365

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RYASVNA 9
           RYAS+NA
Sbjct: 214 RYASINA 220
>NP_001258671
          Length = 276

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RYASVNA 9
           RYAS+NA
Sbjct: 125 RYASINA 131
>NP_001258670
          Length = 325

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RYASVNA 9
           RYAS+NA
Sbjct: 186 RYASINA 192
>NP_001883
          Length = 337

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RYASVNA 9
           RYAS+NA
Sbjct: 186 RYASINA 192
>NP_001885
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RYASVN 8
           RYAS+N
Sbjct: 178 RYASIN 183
>NP_689407
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RYASVN 8
           RYAS+N
Sbjct: 178 RYASIN 183
>NP_001276841
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RYASVN 8
           RYAS+N
Sbjct: 178 RYASIN 183
>NP_001884
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RYASVN 8
           RYAS+N
Sbjct: 178 RYASIN 183
>NP_620693
          Length = 409

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RYASVN 8
           RYAS+N
Sbjct: 178 RYASIN 183
>XP_005256394
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RYASVN 8
           RYAS+N
Sbjct: 178 RYASIN 183
>XP_005256393
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RYASVN 8
           RYAS+N
Sbjct: 178 RYASIN 183
>NP_001188358
          Length = 2170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>NP_036427
          Length = 2220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>NP_001186210
          Length = 2220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_006724247
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_006724246
          Length = 2103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_006724245
          Length = 2191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_006724244
          Length = 2191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_006724243
          Length = 2196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_005261477
          Length = 2200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_005261476
          Length = 2210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_005261474
          Length = 2225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_006724242
          Length = 2226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_005261473
          Length = 2250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
>XP_005261472
          Length = 2255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 MVRYASVNA 9
         M+R A++NA
Sbjct: 1 MIRIAALNA 9
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.121    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 329,534
Number of extensions: 390
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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