Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_808816                                                              18    1482
NP_057691                                                              18    1482
NP_808817                                                              18    1482
XP_005262198                                                           18    1482
NP_114111                                                              18    1935
NP_001154483                                                           18    1935
NP_001154481                                                           18    1935
XP_006716210                                                           18    1935
XP_005250679                                                           18    1935
XP_005250678                                                           18    1935
NP_055597                                                              17    2528
NP_808818                                                              17    2528
NP_001269160                                                           17    2528
XP_005278172                                                           17    2528
XP_005278173                                                           17    2528
XP_005278170                                                           17    2528
XP_005278174                                                           17    2528
XP_005278168                                                           17    2528
XP_005278166                                                           17    2528
XP_005278171                                                           17    2528
XP_005278167                                                           17    2528
NP_057692                                                              16    5631
NP_002105                                                              16    7355
NP_079066                                                              16    7355
NP_001278268                                                           16    7355
NP_079357                                                              16    7355
NP_057323                                                              16    7355
XP_005256732                                                           16    7355
XP_006716543                                                           16    7355
XP_006716542                                                           16    7355
XP_006716541                                                           16    7355
XP_006716539                                                           16    7355
XP_006716538                                                           16    7355
XP_005251368                                                           16    7355
XP_006716537                                                           16    7355
XP_006716536                                                           16    7355
XP_005251364                                                           16    7355
XP_006716535                                                           16    7355
XP_006716534                                                           16    7355
XP_006716533                                                           16    7355
XP_005251363                                                           16    7355
XP_005251362                                                           16    7355
XP_005249099                                                           16    7355
NP_001243084                                                           15    9605
NP_001159450                                                           15    9605
NP_653308                                                              15    9605
NP_001159449                                                           15    9605
NP_031377                                                              15    9605
NP_870992                                                              15    9605
NP_001095139                                                           15    9605
NP_079524                                                              15    9605
NP_003857                                                              15    9605
NP_064612                                                              15    9605
XP_005256332                                                           15    9605
XP_006720659                                                           15    9605
XP_005254992                                                           15    9605
XP_005263382                                                           15    9605
XP_005263381                                                           15    9605
XP_006714466                                                           15    9605
XP_005263380                                                           15    9605
XP_006714465                                                           15    9605
XP_005263379                                                           15    9605
XP_006714464                                                           15    9605
XP_006714463                                                           15    9605
XP_005262913                                                           15    9605
XP_005263937                                                           15    9605
XP_005263936                                                           15    9605
XP_005264493                                                           15    9605
>NP_808816
          Length = 379

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TNE QH
Sbjct: 231 MTVTNEYQH 239
>NP_057691
          Length = 379

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TNE QH
Sbjct: 231 MTVTNEYQH 239
>NP_808817
          Length = 379

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TNE QH
Sbjct: 231 MTVTNEYQH 239
>XP_005262198
          Length = 379

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TNE QH
Sbjct: 231 MTVTNEYQH 239
>NP_114111
          Length = 343

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TN+ QH
Sbjct: 206 MTVTNDHQH 214
>NP_001154483
          Length = 284

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TN+ QH
Sbjct: 171 MTVTNDHQH 179
>NP_001154481
          Length = 308

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TN+ QH
Sbjct: 171 MTVTNDHQH 179
>XP_006716210
          Length = 291

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TN+ QH
Sbjct: 154 MTVTNDHQH 162
>XP_005250679
          Length = 319

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TN+ QH
Sbjct: 182 MTVTNDHQH 190
>XP_005250678
          Length = 354

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M +TN+ QH
Sbjct: 217 MTVTNDHQH 225
>NP_055597
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>NP_808818
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>NP_001269160
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>XP_005278172
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>XP_005278173
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>XP_005278170
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>XP_005278174
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>XP_005278168
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>XP_005278166
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>XP_005278171
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>XP_005278167
          Length = 632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MVITNERQH 9
           M ITN+ QH
Sbjct: 496 MTITNDYQH 504
>NP_057692
          Length = 453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MVITNERQH 9
           M +TN  QH
Sbjct: 315 MTVTNHYQH 323
>NP_002105
          Length = 2718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNERQH 9
           T+ERQH
Sbjct: 501 TDERQH 506
>NP_079066
          Length = 1221

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 312 VYTNDRMH 319
>NP_001278268
          Length = 876

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  VITNERQH 9
          V TN+R H
Sbjct: 18 VYTNDRMH 25
>NP_079357
          Length = 1898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   MVITNERQH 9
           +++TNE+ H
Sbjct: 893 IIVTNEQIH 901
>NP_057323
          Length = 3530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    VITNERQH 9
            V+TN  QH
Sbjct: 3258 VVTNRGQH 3265
>XP_005256732
          Length = 3531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    VITNERQH 9
            V+TN  QH
Sbjct: 3259 VVTNRGQH 3266
>XP_006716543
          Length = 689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 347 VYTNDRMH 354
>XP_006716542
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 347 VYTNDRMH 354
>XP_006716541
          Length = 1032

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 347 VYTNDRMH 354
>XP_006716539
          Length = 1152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 347 VYTNDRMH 354
>XP_006716538
          Length = 1170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 312 VYTNDRMH 319
>XP_005251368
          Length = 1185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 276 VYTNDRMH 283
>XP_006716537
          Length = 1205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 347 VYTNDRMH 354
>XP_006716536
          Length = 1212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 303 VYTNDRMH 310
>XP_005251364
          Length = 1212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 303 VYTNDRMH 310
>XP_006716535
          Length = 1220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 311 VYTNDRMH 318
>XP_006716534
          Length = 1220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 311 VYTNDRMH 318
>XP_006716533
          Length = 1220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 311 VYTNDRMH 318
>XP_005251363
          Length = 1248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 339 VYTNDRMH 346
>XP_005251362
          Length = 1256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           V TN+R H
Sbjct: 347 VYTNDRMH 354
>XP_005249099
          Length = 2026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNERQH 9
           T+ERQH
Sbjct: 501 TDERQH 506
>NP_001243084
          Length = 2290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MVITNERQH 9
            + IT+E QH
Sbjct: 2151 LTITSEYQH 2159
>NP_001159450
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   ITNERQH 9
           +TN+R H
Sbjct: 174 VTNQRTH 180
>NP_653308
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   ITNERQH 9
           +TN+R H
Sbjct: 174 VTNQRTH 180
>NP_001159449
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   ITNERQH 9
           +TN+R H
Sbjct: 174 VTNQRTH 180
>NP_031377
          Length = 1228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   VITNER 7
           V+TNER
Sbjct: 885 VVTNER 890
>NP_870992
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VITNERQH 9
           +IT+ER H
Sbjct: 237 LITHERTH 244
>NP_001095139
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 707 VITGRREH 714
>NP_079524
          Length = 1183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MVITNERQH 9
          +V T+ER+H
Sbjct: 49 LVHTSERRH 57
>NP_003857
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 707 VITGRREH 714
>NP_064612
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VITNERQH 9
           VIT++R H
Sbjct: 539 VITHQRTH 546
>XP_005256332
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VITNERQH 9
           VIT++R H
Sbjct: 390 VITHQRTH 397
>XP_006720659
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VITNERQH 9
          +IT+ER H
Sbjct: 87 LITHERTH 94
>XP_005254992
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VITNERQH 9
           +IT+ER H
Sbjct: 237 LITHERTH 244
>XP_005263382
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 522 VITGRREH 529
>XP_005263381
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 531 VITGRREH 538
>XP_006714466
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 531 VITGRREH 538
>XP_005263380
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 578 VITGRREH 585
>XP_006714465
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 707 VITGRREH 714
>XP_005263379
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 716 VITGRREH 723
>XP_006714464
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 707 VITGRREH 714
>XP_006714463
          Length = 947

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   VITNERQH 9
           VIT  R+H
Sbjct: 716 VITGRREH 723
>XP_005262913
          Length = 1193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   VITNER 7
           V+TNER
Sbjct: 850 VVTNER 855
>XP_005263937
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   ITNERQH 9
           +TN+R H
Sbjct: 98  VTNQRTH 104
>XP_005263936
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   ITNERQH 9
           +TN+R H
Sbjct: 174 VTNQRTH 180
>XP_005264493
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1 MVITNERQH 9
         M I+N+ QH
Sbjct: 1 MAISNKDQH 9
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.127    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 504,327
Number of extensions: 707
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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