Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     665
XP_005262424                                                           19     665
NP_060021                                                              16    5631
NP_001137499                                                           16    5631
NP_055249                                                              16    5631
NP_001137500                                                           16    5631
NP_001137498                                                           16    5631
XP_006717867                                                           16    5631
XP_006717120                                                           16    5631
XP_006717119                                                           16    5631
XP_005266123                                                           16    5631
NP_789786                                                              16    7355
NP_660152                                                              16    7355
NP_001264282                                                           16    7355
XP_005276824                                                           16    7355
XP_005276823                                                           16    7355
XP_005276822                                                           16    7355
XP_006726278                                                           16    7355
XP_005276821                                                           16    7355
XP_006726277                                                           16    7355
XP_005276820                                                           16    7355
XP_005276819                                                           16    7355
XP_005276818                                                           16    7355
XP_005248520                                                           16    7355
XP_005248519                                                           16    7355
XP_005248518                                                           16    7355
XP_006714633                                                           16    7355
XP_005248517                                                           16    7355
XP_006714632                                                           16    7355
XP_005248516                                                           16    7355
XP_005248515                                                           16    7355
XP_005248514                                                           16    7355
XP_006714171                                                           16    7355
NP_077270                                                              15    9605
NP_008879                                                              15    9605
NP_001032                                                              15    9605
NP_004659                                                              15    9605
NP_073595                                                              15    9605
NP_001007526                                                           15    9605
NP_001277284                                                           15    9605
NP_001093900                                                           15    9605
NP_001099001                                                           15    9605
NP_065870                                                              15    9605
NP_001156001                                                           15    9605
XP_006716232                                                           15    9605
XP_006716231                                                           15    9605
XP_005248808                                                           15    9605
XP_005248806                                                           15    9605
XP_005248805                                                           15    9605
XP_005248802                                                           15    9605
XP_005248801                                                           15    9605
XP_005248800                                                           15    9605
XP_005249355                                                           15    9605
XP_006714348                                                           15    9605
XP_006714347                                                           15    9605
NP_001093896                                                           15    9605
NP_001093898                                                           15    9605
NP_066982                                                              15    9605
NP_703146                                                              15    9605
NP_001093897                                                           15    9605
NP_001093899                                                           15    9605
>NP_722576
          Length = 3080

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MVEFSVLGT 9
            MVEF VLGT
Sbjct: 1860 MVEFPVLGT 1868
>XP_005262424
          Length = 2875

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MVEFSVLGT 9
            MVEF VLGT
Sbjct: 1655 MVEFPVLGT 1663
>NP_060021
          Length = 1009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 392 VQFEILGT 399
>NP_001137499
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   MVEFSVLGT 9
           ++EF +LG+
Sbjct: 196 LIEFDILGS 204
>NP_055249
          Length = 597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   MVEFSVLGT 9
           ++EF +LG+
Sbjct: 230 LIEFDILGS 238
>NP_001137500
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   MVEFSVLGT 9
           ++EF +LG+
Sbjct: 230 LIEFDILGS 238
>NP_001137498
          Length = 606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   MVEFSVLGT 9
           ++EF +LG+
Sbjct: 230 LIEFDILGS 238
>XP_006717867
          Length = 896

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 392 VQFEILGT 399
>XP_006717120
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   MVEFSVLGT 9
           ++EF +LG+
Sbjct: 161 LIEFDILGS 169
>XP_006717119
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   MVEFSVLGT 9
           ++EF +LG+
Sbjct: 230 LIEFDILGS 238
>XP_005266123
          Length = 624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   MVEFSVLGT 9
           ++EF +LG+
Sbjct: 230 LIEFDILGS 238
>NP_789786
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 463 EFSVLG 468
>NP_660152
          Length = 159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VEFSVLGT 9
          V FS+LGT
Sbjct: 45 VFFSILGT 52
>NP_001264282
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VEFSVLG 8
           +EFS+LG
Sbjct: 284 IEFSMLG 290
>XP_005276824
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 338 EFSVLG 343
>XP_005276823
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 338 EFSVLG 343
>XP_005276822
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 373 EFSVLG 378
>XP_006726278
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 386 EFSVLG 391
>XP_005276821
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 390 EFSVLG 395
>XP_006726277
          Length = 506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 458 EFSVLG 463
>XP_005276820
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 462 EFSVLG 467
>XP_005276819
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 463 EFSVLG 468
>XP_005276818
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 463 EFSVLG 468
>XP_005248520
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 338 EFSVLG 343
>XP_005248519
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 338 EFSVLG 343
>XP_005248518
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 373 EFSVLG 378
>XP_006714633
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 386 EFSVLG 391
>XP_005248517
          Length = 438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 390 EFSVLG 395
>XP_006714632
          Length = 506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 458 EFSVLG 463
>XP_005248516
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 462 EFSVLG 467
>XP_005248515
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 463 EFSVLG 468
>XP_005248514
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   EFSVLG 8
           EFSVLG
Sbjct: 463 EFSVLG 468
>XP_006714171
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VEFSVLG 8
           +EFS+LG
Sbjct: 126 IEFSMLG 132
>NP_077270
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  MVEFSVLGT 9
          M +FS LGT
Sbjct: 13 MQKFSCLGT 21
>NP_008879
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   MVEFSV 6
           MVEFSV
Sbjct: 129 MVEFSV 134
>NP_001032
          Length = 1827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MVEFSVLG 8
           M+EFS+ G
Sbjct: 619 MLEFSLFG 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MVEFSVLG 8
            M+EFS+ G
Sbjct: 1515 MMEFSLFG 1522
>NP_004659
          Length = 1857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MVEFSVLG 8
            M+EFS+ G
Sbjct: 1541 MMEFSLFG 1548
>NP_073595
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  MVEFSVLGT 9
          M +FS LGT
Sbjct: 13 MQKFSCLGT 21
>NP_001007526
          Length = 1432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MVEFSVLGT 9
            MVE +V GT
Sbjct: 1130 MVETAVFGT 1138
>NP_001277284
          Length = 1429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MVEFSVLGT 9
            MVE +V GT
Sbjct: 995  MVETAVFGT 1003
>NP_001093900
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 327 VQFKLLGT 334
>NP_001099001
          Length = 1319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>NP_065870
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>NP_001156001
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>XP_006716232
          Length = 2753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MVEFSVLG 8
            M+EFS+ G
Sbjct: 1541 MMEFSLFG 1548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MVEFSVLG 8
            M+EFS+ G
Sbjct: 2437 MMEFSLFG 2444
>XP_006716231
          Length = 2753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MVEFSVLG 8
            M+EFS+ G
Sbjct: 1541 MMEFSLFG 1548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MVEFSVLG 8
            M+EFS+ G
Sbjct: 2437 MMEFSLFG 2444
>XP_005248808
          Length = 1121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>XP_005248806
          Length = 1317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>XP_005248805
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>XP_005248802
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>XP_005248801
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>XP_005248800
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MVEFSV 6
          MVEFSV
Sbjct: 7  MVEFSV 12
>XP_005249355
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  MVEFSVLGT 9
          M +FS LGT
Sbjct: 13 MQKFSCLGT 21
>XP_006714348
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 289 VQFKLLGT 296
>XP_006714347
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 338 VQFKLLGT 345
>NP_001093896
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 419 VQFKLLGT 426
>NP_001093898
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 370 VQFKLLGT 377
>NP_066982
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 419 VQFKLLGT 426
>NP_703146
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  MVEFSVLG 8
          +VEF++LG
Sbjct: 9  VVEFTLLG 16
>NP_001093897
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 418 VQFKLLGT 425
>NP_001093899
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEFSVLGT 9
           V+F +LGT
Sbjct: 369 VQFKLLGT 376
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.138    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 411,847
Number of extensions: 654
Number of successful extensions: 64
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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