Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           19     665
NP_036462                                                              19     665
NP_001243397                                                           19     665
XP_005269721                                                           19     665
NP_000775                                                              17    3301
XP_006724219                                                           17    3301
XP_006724218                                                           17    3301
XP_006724217                                                           17    3301
NP_689726                                                              17    3301
NP_115543                                                              16    7355
XP_005255740                                                           16    7355
XP_006721041                                                           16    7355
XP_006721040                                                           16    7355
XP_005255739                                                           16    7355
NP_001140                                                              15    9605
NP_001191332                                                           15    9605
NP_001191333                                                           15    9605
NP_066267                                                              15    9605
NP_001139187                                                           15    9605
XP_005269773                                                           15    9605
XP_006717866                                                           15    9605
XP_005269772                                                           15    9605
XP_006717865                                                           15    9605
XP_006717864                                                           15    9605
XP_006717863                                                           15    9605
XP_006717862                                                           15    9605
XP_006717861                                                           15    9605
XP_006717860                                                           15    9605
XP_006717859                                                           15    9605
XP_006717858                                                           15    9605
XP_006717857                                                           15    9605
XP_006717856                                                           15    9605
XP_006717855                                                           15    9605
XP_006717854                                                           15    9605
XP_006717853                                                           15    9605
XP_006717852                                                           15    9605
XP_006717851                                                           15    9605
XP_006717850                                                           15    9605
XP_006717849                                                           15    9605
XP_006717848                                                           15    9605
XP_006717847                                                           15    9605
XP_006717846                                                           15    9605
XP_006717845                                                           15    9605
XP_006716050                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSVNLMSAP 9
            MSVNLM AP
Sbjct: 1675 MSVNLMPAP 1683
>NP_036462
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSVNLMSAP 9
            MSVNLM AP
Sbjct: 1967 MSVNLMPAP 1975
>NP_001243397
          Length = 1890

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSVNLMSAP 9
            MSVNLM AP
Sbjct: 1784 MSVNLMPAP 1792
>XP_005269721
          Length = 2073

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSVNLMSAP 9
            MSVNLM AP
Sbjct: 1967 MSVNLMPAP 1975
>NP_000775
          Length = 531

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   MSVNLMSAP 9
           M VNL SAP
Sbjct: 104 MHVNLASAP 112
>XP_006724219
          Length = 1157

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSVNLMSAP 9
           M +NL+SAP
Sbjct: 516 MCLNLLSAP 524
>XP_006724218
          Length = 1200

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSVNLMSAP 9
           M +NL+SAP
Sbjct: 594 MCLNLLSAP 602
>XP_006724217
          Length = 1235

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSVNLMSAP 9
           M +NL+SAP
Sbjct: 594 MCLNLLSAP 602
>NP_689726
          Length = 1274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSVNLMSAP 9
           M +NL+SAP
Sbjct: 633 MCLNLLSAP 641
>NP_115543
          Length = 813

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVNLMSA 8
           SVN+MSA
Sbjct: 300 SVNIMSA 306
>XP_005255740
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVNLMSA 8
           SVN+MSA
Sbjct: 310 SVNIMSA 316
>XP_006721041
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVNLMSA 8
           SVN+MSA
Sbjct: 167 SVNIMSA 173
>XP_006721040
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVNLMSA 8
           SVN+MSA
Sbjct: 148 SVNIMSA 154
>XP_005255739
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVNLMSA 8
           SVN+MSA
Sbjct: 310 SVNIMSA 316
>NP_001140
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 106 NVNLVSSP 113
>NP_001191332
          Length = 1861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 966 NVNLVSSP 973
>NP_001191333
          Length = 1868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 973 NVNLVSSP 980
>NP_066267
          Length = 4377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 972 NVNLVSSP 979
>NP_001139187
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VNLMSAP 9
           VNL++AP
Sbjct: 416 VNLLTAP 422
>XP_005269773
          Length = 1867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 972 NVNLVSSP 979
>XP_006717866
          Length = 1877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 990 NVNLVSSP 997
>XP_005269772
          Length = 1885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 990 NVNLVSSP 997
>XP_006717865
          Length = 1898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717864
          Length = 1924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717863
          Length = 1972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717862
          Length = 1981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717861
          Length = 1984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717860
          Length = 1993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717859
          Length = 2758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717858
          Length = 2775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717857
          Length = 2794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717856
          Length = 2833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717855
          Length = 2837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717854
          Length = 2852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717853
          Length = 2854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    SVNLMSAP 9
            +VNL+S+P
Sbjct: 994  NVNLVSSP 1001
>XP_006717852
          Length = 3508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 101 NVNLVSSP 108
>XP_006717851
          Length = 3513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 106 NVNLVSSP 113
>XP_006717850
          Length = 4364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 957 NVNLVSSP 964
>XP_006717849
          Length = 4383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 976 NVNLVSSP 983
>XP_006717848
          Length = 4392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 985 NVNLVSSP 992
>XP_006717847
          Length = 4395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 988 NVNLVSSP 995
>XP_006717846
          Length = 4396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 989 NVNLVSSP 996
>XP_006717845
          Length = 4397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVNLMSAP 9
           +VNL+S+P
Sbjct: 990 NVNLVSSP 997
>XP_006716050
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VNLMSAP 9
           VNL++AP
Sbjct: 416 VNLLTAP 422
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.115    0.299 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 374,498
Number of extensions: 430
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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