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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              17    2528
NP_001035957                                                           17    2528
XP_006721991                                                           17    2528
XP_006721990                                                           17    2528
XP_006721989                                                           17    2528
XP_005258041                                                           17    2528
XP_006721988                                                           17    2528
XP_006721987                                                           17    2528
XP_006721986                                                           17    2528
XP_005258040                                                           17    2528
XP_006721985                                                           17    2528
NP_079229                                                              17    4312
XP_005253995                                                           17    4312
XP_006719669                                                           17    4312
NP_064578                                                              16    5631
XP_006718702                                                           16    5631
XP_006718701                                                           16    5631
XP_006718700                                                           16    5631
XP_005274169                                                           16    5631
XP_005274166                                                           16    5631
XP_005274165                                                           16    5631
XP_005274163                                                           16    5631
NP_001273574                                                           15    9605
NP_001110                                                              15    9605
NP_054909                                                              15    9605
NP_054908                                                              15    9605
NP_789771                                                              15    9605
XP_005247994                                                           15    9605
XP_005247993                                                           15    9605
XP_005247992                                                           15    9605
XP_005247991                                                           15    9605
XP_005247990                                                           15    9605

>NP_000258
          Length = 2818

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1421 MSKILQSIA 1429



>NP_001035957
          Length = 2839

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1442 MSKILQSIA 1450



>XP_006721991
          Length = 1632

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1452 MSKILQSIA 1460



>XP_006721990
          Length = 2823

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1452 MSKILQSIA 1460



>XP_006721989
          Length = 2823

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1452 MSKILQSIA 1460



>XP_005258041
          Length = 2836

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1421 MSKILQSIA 1429



>XP_006721988
          Length = 2846

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1431 MSKILQSIA 1439



>XP_006721987
          Length = 2849

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1452 MSKILQSIA 1460



>XP_006721986
          Length = 2854

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1439 MSKILQSIA 1447



>XP_005258040
          Length = 2857

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1442 MSKILQSIA 1450



>XP_006721985
          Length = 2867

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSMILQSIA 9
            MS ILQSIA
Sbjct: 1452 MSKILQSIA 1460



>NP_079229
          Length = 972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   MSMILQSIA 9
           MS+I+QSI+
Sbjct: 154 MSLIMQSIS 162



>XP_005253995
          Length = 836

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  MSMILQSIA 9
          MS+I+QSI+
Sbjct: 18 MSLIMQSIS 26



>XP_006719669
          Length = 944

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   MSMILQSIA 9
           MS+I+QSI+
Sbjct: 126 MSLIMQSIS 134



>NP_064578
          Length = 1322

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   MSMILQSIA 9
           MS I+QSIA
Sbjct: 241 MSNIMQSIA 249



>XP_006718702
          Length = 1151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   MSMILQSIA 9
           MS I+QSIA
Sbjct: 191 MSNIMQSIA 199



>XP_006718701
          Length = 1309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   MSMILQSIA 9
           MS I+QSIA
Sbjct: 242 MSNIMQSIA 250



>XP_006718700
          Length = 1216

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   MSMILQSIA 9
           MS I+QSIA
Sbjct: 256 MSNIMQSIA 264



>XP_005274169
          Length = 1272

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   MSMILQSIA 9
           MS I+QSIA
Sbjct: 205 MSNIMQSIA 213



>XP_005274166
          Length = 1323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   MSMILQSIA 9
           MS I+QSIA
Sbjct: 256 MSNIMQSIA 264



>XP_005274165
          Length = 1323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   MSMILQSIA 9
           MS I+QSIA
Sbjct: 242 MSNIMQSIA 250



>XP_005274163
          Length = 1337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   MSMILQSIA 9
           MS I+QSIA
Sbjct: 256 MSNIMQSIA 264



>NP_001273574
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>NP_001110
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>NP_054909
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>NP_054908
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>NP_789771
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>XP_005247994
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>XP_005247993
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>XP_005247992
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>XP_005247991
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



>XP_005247990
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  MSMILQSIA 9
          +SMILQS A
Sbjct: 58 VSMILQSPA 66



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.129    0.281 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 205,430
Number of extensions: 134
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)