Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              20     509
NP_689777                                                              17    3301
NP_060360                                                              17    3301
NP_056058                                                              17    3301
XP_006716574                                                           17    3301
XP_006716573                                                           17    3301
XP_005250858                                                           17    3301
XP_005250857                                                           17    3301
NP_001257903                                                           17    4312
XP_006721269                                                           17    4312
NP_000636                                                              16    5631
NP_005602                                                              16    5631
NP_060501                                                              16    5631
NP_148936                                                              16    5631
NP_001245390                                                           16    5631
NP_006703                                                              16    5631
XP_005256140                                                           16    5631
XP_006718992                                                           16    5631
XP_005249990                                                           16    5631
XP_005249989                                                           16    5631
XP_005264894                                                           16    5631
NP_001240838                                                           16    7355
NP_062553                                                              16    7355
NP_001161375                                                           16    7355
NP_001276336                                                           16    7355
NP_001276335                                                           16    7355
NP_073573                                                              16    7355
NP_115544                                                              16    7355
NP_443134                                                              16    7355
XP_006713793                                                           16    7355
NP_149081                                                              15    9605
NP_683701                                                              15    9605
NP_055483                                                              15    9605
NP_000043                                                              15    9605
NP_001269153                                                           15    9605
NP_001138351                                                           15    9605
NP_001269973                                                           15    9605
NP_065076                                                              15    9605
NP_055805                                                              15    9605
NP_001269972                                                           15    9605
NP_079007                                                              15    9605
NP_919277                                                              15    9605
XP_006723662                                                           15    9605
XP_005260825                                                           15    9605
XP_006723661                                                           15    9605
XP_005256206                                                           15    9605
XP_005267555                                                           15    9605
XP_006720166                                                           15    9605
XP_005267550                                                           15    9605
XP_005267549                                                           15    9605
XP_005267548                                                           15    9605
XP_006720165                                                           15    9605
XP_006720164                                                           15    9605
XP_006720163                                                           15    9605
XP_006720162                                                           15    9605
XP_006720161                                                           15    9605
XP_005266922                                                           15    9605
XP_006711971                                                           15    9605
XP_006711970                                                           15    9605
XP_006711969                                                           15    9605
XP_005246249                                                           15    9605
XP_006711968                                                           15    9605
XP_006711967                                                           15    9605
NP_001025029                                                           15    9605
>NP_000312
          Length = 928

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           MSLL CALE
Sbjct: 484 MSLLACALE 492
>NP_689777
          Length = 3997

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           + ++VCALE
Sbjct: 595 LKMIVCALE 603
>NP_060360
          Length = 4022

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           + ++VCALE
Sbjct: 595 LKMIVCALE 603
>NP_056058
          Length = 863

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           + ++VCALE
Sbjct: 595 LKMIVCALE 603
>XP_006716574
          Length = 968

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           + ++VCALE
Sbjct: 595 LKMIVCALE 603
>XP_006716573
          Length = 1776

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           + ++VCALE
Sbjct: 595 LKMIVCALE 603
>XP_005250858
          Length = 4022

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           + ++VCALE
Sbjct: 595 LKMIVCALE 603
>XP_005250857
          Length = 4022

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           + ++VCALE
Sbjct: 595 LKMIVCALE 603
>NP_001257903
          Length = 5121

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLVCALE 9
            SLLVC +E
Sbjct: 4133 SLLVCPME 4140
>XP_006721269
          Length = 5138

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLVCALE 9
            SLLVC +E
Sbjct: 4150 SLLVCPME 4157
>NP_000636
          Length = 1515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1 MSLLVCA 7
         MSLL CA
Sbjct: 1 MSLLTCA 7
>NP_005602
          Length = 1139

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SLLVCALE 9
           SLL C LE
Sbjct: 531 SLLACCLE 538
>NP_060501
          Length = 1151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MSLLVCALE 9
           MSL VC L+
Sbjct: 893 MSLAVCELD 901
>NP_148936
          Length = 408

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LVCALE 9
          LVCALE
Sbjct: 35 LVCALE 40
>NP_001245390
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LVCALE 9
           LVCALE
Sbjct: 176 LVCALE 181
>NP_006703
          Length = 549

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LVCALE 9
           LVCALE
Sbjct: 176 LVCALE 181
>XP_005256140
          Length = 1065

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SLLVCALE 9
           SLL C LE
Sbjct: 457 SLLACCLE 464
>XP_006718992
          Length = 178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   MSLLVCAL 8
           M LLVCA+
Sbjct: 112 MILLVCAI 119
>XP_005249990
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LVCALE 9
           LVCALE
Sbjct: 142 LVCALE 147
>XP_005249989
          Length = 515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LVCALE 9
           LVCALE
Sbjct: 142 LVCALE 147
>XP_005264894
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MSLLVCALE 9
           MSL VC L+
Sbjct: 812 MSLAVCELD 820
>NP_001240838
          Length = 138

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   MSLLVCAL 8
           MSL VC+L
Sbjct: 120 MSLKVCSL 127
>NP_062553
          Length = 159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LVCALE 9
          L+CALE
Sbjct: 93 LICALE 98
>NP_001161375
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLLVCAL 8
           SLL CAL
Sbjct: 377 SLLACAL 383
>NP_001276336
          Length = 392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLLVCAL 8
           SLL CAL
Sbjct: 294 SLLACAL 300
>NP_001276335
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLLVCAL 8
           SLL CAL
Sbjct: 270 SLLACAL 276
>NP_073573
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLLVCAL 8
           SLL CAL
Sbjct: 416 SLLACAL 422
>NP_115544
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLLVCALE 9
           +LL CALE
Sbjct: 569 NLLSCALE 576
>NP_443134
          Length = 1099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   LLVCALE 9
           LLVC LE
Sbjct: 552 LLVCPLE 558
>XP_006713793
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLLVCAL 8
           SLL CAL
Sbjct: 377 SLLACAL 383
>NP_149081
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>NP_683701
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>NP_055483
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>NP_000043
          Length = 1500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SLLVCA 7
           SLL+CA
Sbjct: 899 SLLICA 904
>NP_001269153
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   SLLVCA 7
           SLL+CA
Sbjct: 821 SLLICA 826
>NP_001138351
          Length = 198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LLVCAL 8
           LL+CAL
Sbjct: 161 LLICAL 166
>NP_001269973
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1436 VSLLLCLLD 1444
>NP_065076
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1257 VSLLLCLLD 1265
>NP_055805
          Length = 2036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1389 VSLLLCLLD 1397
>NP_001269972
          Length = 2049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1402 VSLLLCLLD 1410
>NP_079007
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SLLVCALE 9
           S  VCALE
Sbjct: 589 SACVCALE 596
>NP_919277
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1389 VSLLLCLLD 1397
>XP_006723662
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1304 VSLLLCLLD 1312
>XP_005260825
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1257 VSLLLCLLD 1265
>XP_006723661
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1304 VSLLLCLLD 1312
>XP_005256206
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   SLLVCALE 9
           S  VCALE
Sbjct: 589 SACVCALE 596
>XP_005267555
          Length = 1325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSLLVCALE 9
           +SLL+C L+
Sbjct: 630 VSLLLCLLD 638
>XP_006720166
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1436 VSLLLCLLD 1444
>XP_005267550
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1389 VSLLLCLLD 1397
>XP_005267549
          Length = 2130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1436 VSLLLCLLD 1444
>XP_005267548
          Length = 2131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1436 VSLLLCLLD 1444
>XP_006720165
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1895 VSLLLCLLD 1903
>XP_006720164
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1895 VSLLLCLLD 1903
>XP_006720163
          Length = 2543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1848 VSLLLCLLD 1856
>XP_006720162
          Length = 2589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1895 VSLLLCLLD 1903
>XP_006720161
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MSLLVCALE 9
            +SLL+C L+
Sbjct: 1895 VSLLLCLLD 1903
>XP_005266922
          Length = 408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  MSLLVCAL 8
          +SLL+C +
Sbjct: 70 LSLLICGI 77
>XP_006711971
          Length = 1517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>XP_006711970
          Length = 1948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>XP_006711969
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>XP_005246249
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>XP_006711968
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>XP_006711967
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLVCALE 9
           LLVCA++
Sbjct: 131 LLVCAVD 137
>NP_001025029
          Length = 408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  MSLLVCAL 8
          +SLL+C +
Sbjct: 70 LSLLICGI 77
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.138    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 558,647
Number of extensions: 574
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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