Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721991                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_000188                                                              16    5631
XP_005252027                                                           16    5631
XP_006717157                                                           16    5631
NP_001275743                                                           16    7355
NP_115826                                                              16    7355
NP_067013                                                              16    7355
XP_006725233                                                           16    7355
XP_006725232                                                           16    7355
XP_006725231                                                           16    7355
XP_006720285                                                           16    7355
XP_005267988                                                           16    7355
XP_005267987                                                           16    7355
XP_006716698                                                           16    7355
XP_006716697                                                           16    7355
XP_006716696                                                           16    7355
XP_006716695                                                           16    7355
XP_006716694                                                           16    7355
XP_006716693                                                           16    7355
XP_006716692                                                           16    7355
XP_006716691                                                           16    7355
XP_006716690                                                           16    7355
XP_006716689                                                           16    7355
XP_005271143                                                           16    7355
XP_005271142                                                           16    7355
XP_005271141                                                           16    7355
NP_478144                                                              16    7355
NP_001122400                                                           15    9605
NP_001243465                                                           15    9605
NP_062828                                                              15    9605
XP_006719049                                                           15    9605
XP_005246589                                                           15    9605
XP_006712561                                                           15    9605
NP_002185                                                              15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1149 MSNLLNANV 1157
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1149 MSNLLNANV 1157
>XP_006721991
          Length = 1632

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1159 MSNLLNANV 1167
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1159 MSNLLNANV 1167
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1159 MSNLLNANV 1167
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1149 MSNLLNANV 1157
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1159 MSNLLNANV 1167
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1159 MSNLLNANV 1167
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1146 MSNLLNANV 1154
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1149 MSNLLNANV 1157
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MSKLLNANV 9
            MS LLNANV
Sbjct: 1159 MSNLLNANV 1167
>NP_000188
          Length = 310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MSKLLNANV 9
           M+K LN NV
Sbjct: 235 MTKYLNTNV 243
>XP_005252027
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MSKLLNANV 9
           M+K LN NV
Sbjct: 115 MTKYLNTNV 123
>XP_006717157
          Length = 256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MSKLLNANV 9
           M+K LN NV
Sbjct: 181 MTKYLNTNV 189
>NP_001275743
          Length = 1632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1337 LAELLNSNV 1345
>NP_115826
          Length = 1641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1346 LAELLNSNV 1354
>NP_067013
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLLNANV 9
           SKL+N NV
Sbjct: 255 SKLVNLNV 262
>XP_006725233
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSKLLNANV 9
           +SKLLN+ V
Sbjct: 316 VSKLLNSGV 324
>XP_006725232
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSKLLNANV 9
           +SKLLN+ V
Sbjct: 316 VSKLLNSGV 324
>XP_006725231
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSKLLNANV 9
           +SKLLN+ V
Sbjct: 316 VSKLLNSGV 324
>XP_006720285
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSKLLNANV 9
           +SKLLN+ V
Sbjct: 316 VSKLLNSGV 324
>XP_005267988
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSKLLNANV 9
           +SKLLN+ V
Sbjct: 316 VSKLLNSGV 324
>XP_005267987
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSKLLNANV 9
           +SKLLN+ V
Sbjct: 316 VSKLLNSGV 324
>XP_006716698
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1346 LAELLNSNV 1354
>XP_006716697
          Length = 1578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1346 LAELLNSNV 1354
>XP_006716696
          Length = 1585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1278 LAELLNSNV 1286
>XP_006716695
          Length = 1585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1278 LAELLNSNV 1286
>XP_006716694
          Length = 1632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1337 LAELLNSNV 1345
>XP_006716693
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1337 LAELLNSNV 1345
>XP_006716692
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1337 LAELLNSNV 1345
>XP_006716691
          Length = 1653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1346 LAELLNSNV 1354
>XP_006716690
          Length = 1653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1346 LAELLNSNV 1354
>XP_006716689
          Length = 1653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    MSKLLNANV 9
            +++LLN+NV
Sbjct: 1346 LAELLNSNV 1354
>XP_005271143
          Length = 532

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLLNANV 9
           SKL+N NV
Sbjct: 255 SKLVNLNV 262
>XP_005271142
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLLNANV 9
           SKL+N NV
Sbjct: 255 SKLVNLNV 262
>XP_005271141
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SKLLNANV 9
           SKL+N NV
Sbjct: 255 SKLVNLNV 262
>NP_478144
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MSKLLNANV 9
           +SKLLN+ V
Sbjct: 423 VSKLLNSGV 431
>NP_001122400
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSKLLNAN 8
           +SK+LN N
Sbjct: 107 LSKVLNGN 114
>NP_001243465
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MSKLLN 6
          MSKLLN
Sbjct: 52 MSKLLN 57
>NP_062828
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  MSKLLN 6
          MSKLLN
Sbjct: 61 MSKLLN 66
>XP_006719049
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1 MSKLLN 6
         MSKLLN
Sbjct: 1 MSKLLN 6
>XP_005246589
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSKLLNAN 8
           +SK+LN N
Sbjct: 107 LSKVLNGN 114
>XP_006712561
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSKLLNAN 8
           +SK+LN N
Sbjct: 107 LSKVLNGN 114
>NP_002185
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSKLLNAN 8
           +SK+LN N
Sbjct: 107 LSKVLNGN 114
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.121    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 337,469
Number of extensions: 465
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package