Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_937816                                                              17    3301
NP_067003                                                              17    3301
NP_001181939                                                           17    3301
NP_937817                                                              17    3301
NP_659001                                                              17    4312
NP_001154178                                                           17    4312
NP_001231293                                                           17    4312
NP_003834                                                              17    4312
NP_001073948                                                           17    4312
NP_001171164                                                           17    4312
XP_006719949                                                           17    4312
XP_006719948                                                           17    4312
XP_005266635                                                           17    4312
XP_006719947                                                           17    4312
XP_006719946                                                           17    4312
XP_006719945                                                           17    4312
XP_005248625                                                           17    4312
XP_006714732                                                           17    4312
NP_001148                                                              16    5631
NP_665875                                                              16    5631
NP_001265336                                                           16    5631
NP_001265337                                                           16    5631
NP_001265338                                                           16    5631
NP_665876                                                              16    5631
NP_000129                                                              16    5631
NP_059116                                                              16    5631
NP_036564                                                              16    5631
XP_005267816                                                           16    5631
XP_006717877                                                           16    5631
XP_006717876                                                           16    5631
XP_005269799                                                           16    5631
XP_005269798                                                           16    5631
XP_006711735                                                           16    5631
XP_005245698                                                           16    5631
NP_001138887                                                           16    5631
NP_079235                                                              16    7355
NP_848563                                                              16    7355
NP_663615                                                              16    7355
NP_005083                                                              16    7355
NP_061026                                                              16    7355
NP_001631                                                              16    7355
NP_001129316                                                           16    7355
NP_056508                                                              16    7355
XP_005260806                                                           16    7355
XP_006723598                                                           16    7355
XP_006719671                                                           16    7355
XP_005265155                                                           16    7355
XP_005265154                                                           16    7355
NP_689673                                                              16    7355
NP_001073881                                                           15    9605
NP_001035111                                                           15    9605
NP_001184033                                                           15    9605
NP_542970                                                              15    9605
NP_001035112                                                           15    9605
XP_005260727                                                           15    9605
XP_005260726                                                           15    9605
XP_006718903                                                           15    9605
XP_006718902                                                           15    9605
XP_006713622                                                           15    9605
XP_005247320                                                           15    9605
XP_005247319                                                           15    9605
XP_005247318                                                           15    9605
XP_005247315                                                           15    9605
XP_005247314                                                           15    9605
XP_005247313                                                           15    9605
XP_005247312                                                           15    9605
>NP_937816
          Length = 602

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MSENISGT 8
           ++EN+SGT
Sbjct: 113 LTENVSGT 120
>NP_067003
          Length = 607

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MSENISGT 8
           ++EN+SGT
Sbjct: 118 LTENVSGT 125
>NP_001181939
          Length = 556

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  MSENISGT 8
          ++EN+SGT
Sbjct: 67 LTENVSGT 74
>NP_937817
          Length = 626

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MSENISGT 8
           ++EN+SGT
Sbjct: 113 LTENVSGT 120
>NP_659001
          Length = 688

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 597 ENISGKY 603
>NP_001154178
          Length = 646

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 555 ENISGKY 561
>NP_001231293
          Length = 1392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSENISGT 8
           +SEN+ GT
Sbjct: 116 LSENVEGT 123
>NP_003834
          Length = 668

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 577 ENISGKY 583
>NP_001073948
          Length = 1731

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSENISGT 8
           +SEN+ GT
Sbjct: 429 LSENVEGT 436
>NP_001171164
          Length = 1705

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSENISGT 8
           +SEN+ GT
Sbjct: 429 LSENVEGT 436
>XP_006719949
          Length = 619

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 528 ENISGKY 534
>XP_006719948
          Length = 648

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 557 ENISGKY 563
>XP_005266635
          Length = 665

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 574 ENISGKY 580
>XP_006719947
          Length = 666

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 575 ENISGKY 581
>XP_006719946
          Length = 668

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 577 ENISGKY 583
>XP_006719945
          Length = 668

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           ENISG Y
Sbjct: 577 ENISGKY 583
>XP_005248625
          Length = 1418

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSENISGT 8
           +SEN+ GT
Sbjct: 116 LSENVEGT 123
>XP_006714732
          Length = 1633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSENISGT 8
           +SEN+ GT
Sbjct: 331 LSENVEGT 338
>NP_001148
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 57 MAANMSGTF 65
>NP_665875
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 57 MAANMSGTF 65
>NP_001265336
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 57 MAANMSGTF 65
>NP_001265337
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 57 MAANMSGTF 65
>NP_001265338
          Length = 472

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 24 MAANMSGTF 32
>NP_665876
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 57 MAANMSGTF 65
>NP_000129
          Length = 2871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           EN+ GTY
Sbjct: 740 ENLRGTY 746
>NP_059116
          Length = 781

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SENISGT 8
           SENISG+
Sbjct: 596 SENISGS 602
>NP_036564
          Length = 1290

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MSENISG 7
           +SEN+SG
Sbjct: 511 LSENVSG 517
>XP_005267816
          Length = 773

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SENISGT 8
           SENISG+
Sbjct: 588 SENISGS 594
>XP_006717877
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 57 MAANMSGTF 65
>XP_006717876
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 57 MAANMSGTF 65
>XP_005269799
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  MSENISGTY 9
          M+ N+SGT+
Sbjct: 57 MAANMSGTF 65
>XP_005269798
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MSENISGTY 9
           M+ N+SGT+
Sbjct: 157 MAANMSGTF 165
>XP_006711735
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MSENISG 7
           +SEN+SG
Sbjct: 512 LSENVSG 518
>XP_005245698
          Length = 1292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MSENISG 7
           +SEN+SG
Sbjct: 512 LSENVSG 518
>NP_001138887
          Length = 1291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MSENISG 7
           +SEN+SG
Sbjct: 511 LSENVSG 517
>NP_079235
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  MSENISGT 8
          M+E +SGT
Sbjct: 20 MAETVSGT 27
>NP_848563
          Length = 747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           +SE  SGTY
Sbjct: 108 LSEVTSGTY 116
>NP_663615
          Length = 402

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  ENISGTY 9
          EN+SG Y
Sbjct: 41 ENVSGYY 47
>NP_005083
          Length = 199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   ENISGTY 9
           +N+ GTY
Sbjct: 156 QNVGGTY 162
>NP_061026
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 300 LTENKDGTY 308
>NP_001631
          Length = 732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MSENISGTY 9
           + EN SG Y
Sbjct: 352 LGENFSGIY 360
>NP_001129316
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 301 LTENKDGTY 309
>NP_056508
          Length = 942

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MSENISGT 8
           M EN++GT
Sbjct: 353 MLENVTGT 360
>XP_005260806
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 194 LTENKDGTY 202
>XP_006723598
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 344 LTENKDGTY 352
>XP_006719671
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  MSENISGT 8
          M+E +SGT
Sbjct: 20 MAETVSGT 27
>XP_005265155
          Length = 631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MSENISGTY 9
           + EN SG Y
Sbjct: 251 LGENFSGIY 259
>XP_005265154
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MSENISGTY 9
           + EN SG Y
Sbjct: 306 LGENFSGIY 314
>NP_689673
          Length = 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ENISGT 8
           EN+SGT
Sbjct: 135 ENVSGT 140
>NP_001073881
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 595 MNESAPGTY 603
>NP_001035111
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 302 VTENKDGTY 310
>NP_001184033
          Length = 3972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    ENISGT 8
            EN+SGT
Sbjct: 1600 ENLSGT 1605
>NP_542970
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 302 VTENKDGTY 310
>NP_001035112
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 302 VTENKDGTY 310
>XP_005260727
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 302 VTENKDGTY 310
>XP_005260726
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           ++EN  GTY
Sbjct: 302 VTENKDGTY 310
>XP_006718903
          Length = 2673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ENISGT 8
           EN+SGT
Sbjct: 301 ENLSGT 306
>XP_006718902
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ENISGT 8
           EN+SGT
Sbjct: 592 ENLSGT 597
>XP_006713622
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 595 MNESAPGTY 603
>XP_005247320
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 595 MNESAPGTY 603
>XP_005247319
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 595 MNESAPGTY 603
>XP_005247318
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 595 MNESAPGTY 603
>XP_005247315
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 595 MNESAPGTY 603
>XP_005247314
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 595 MNESAPGTY 603
>XP_005247313
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 596 MNESAPGTY 604
>XP_005247312
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MSENISGTY 9
           M+E+  GTY
Sbjct: 631 MNESAPGTY 639
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.117    0.305 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 566,033
Number of extensions: 1119
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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