Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1482
XP_006718907                                                           18    1482
XP_006718906                                                           18    1482
XP_005271619                                                           18    1482
XP_005271618                                                           18    1482
NP_001245322                                                           17    4312
XP_005274377                                                           17    4312
NP_001018065                                                           16    7355
NP_077308                                                              16    7355
NP_001229569                                                           16    7355
NP_001271279                                                           16    7355
NP_071926                                                              16    7355
XP_005274808                                                           16    7355
XP_005274807                                                           16    7355
XP_005274806                                                           16    7355
XP_006724909                                                           16    7355
XP_006714856                                                           16    7355
XP_005268556                                                           16    7355
XP_006714855                                                           16    7355
XP_006714854                                                           16    7355
XP_005268555                                                           16    7355
XP_005268554                                                           16    7355
NP_001025190                                                           16    7355
NP_689995                                                              16    7355
NP_000490                                                              15    9605
NP_056040                                                              15    9605
NP_001234926                                                           15    9605
NP_002947                                                              15    9605
NP_937883                                                              15    9605
XP_005254242                                                           15    9605
XP_006719618                                                           15    9605
XP_006719617                                                           15    9605
XP_006719616                                                           15    9605
XP_006719615                                                           15    9605
XP_006719614                                                           15    9605
XP_005253652                                                           15    9605
XP_005253651                                                           15    9605
XP_005253650                                                           15    9605
XP_005251811                                                           15    9605
XP_005251810                                                           15    9605
XP_005251809                                                           15    9605
XP_005251808                                                           15    9605
XP_005251807                                                           15    9605
XP_005251805                                                           15    9605
XP_005251803                                                           15    9605
XP_006717050                                                           15    9605
XP_005251802                                                           15    9605
XP_006717049                                                           15    9605
XP_006717048                                                           15    9605
XP_006717047                                                           15    9605
XP_006717046                                                           15    9605
XP_006717045                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   MQEISSLV 8
           MQEISSLV
Sbjct: 94  MQEISSLV 101
>XP_006718907
          Length = 3050

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   MQEISSLV 8
           MQEISSLV
Sbjct: 94  MQEISSLV 101
>XP_006718906
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   MQEISSLV 8
           MQEISSLV
Sbjct: 94  MQEISSLV 101
>XP_005271619
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   MQEISSLV 8
           MQEISSLV
Sbjct: 94  MQEISSLV 101
>XP_005271618
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   MQEISSLV 8
           MQEISSLV
Sbjct: 94  MQEISSLV 101
>NP_001245322
          Length = 648

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MQEISSLV 8
           MQE+SS+V
Sbjct: 147 MQEVSSVV 154
>XP_005274377
          Length = 678

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   MQEISSLV 8
           MQE+SS+V
Sbjct: 147 MQEVSSVV 154
>NP_001018065
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           MQE+SSL
Sbjct: 284 MQELSSL 290
>NP_077308
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           MQE+SSL
Sbjct: 309 MQELSSL 315
>NP_001229569
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           MQE+SSL
Sbjct: 285 MQELSSL 291
>NP_001271279
          Length = 345

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QEISSLVN 9
           +E+S+LVN
Sbjct: 152 EEVSNLVN 159
>NP_071926
          Length = 1544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    MQEISSLV 8
            +QE+SSL+
Sbjct: 1486 LQELSSLI 1493
>XP_005274808
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           MQE+SSL
Sbjct: 310 MQELSSL 316
>XP_005274807
          Length = 202

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           MQE+SSL
Sbjct: 195 MQELSSL 201
>XP_005274806
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           MQE+SSL
Sbjct: 240 MQELSSL 246
>XP_006724909
          Length = 248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           MQE+SSL
Sbjct: 241 MQELSSL 247
>XP_006714856
          Length = 1346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    MQEISSLV 8
            +QE+SSL+
Sbjct: 1288 LQELSSLI 1295
>XP_005268556
          Length = 1466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    MQEISSLV 8
            +QE+SSL+
Sbjct: 1408 LQELSSLI 1415
>XP_006714855
          Length = 1473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    MQEISSLV 8
            +QE+SSL+
Sbjct: 1415 LQELSSLI 1422
>XP_006714854
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    MQEISSLV 8
            +QE+SSL+
Sbjct: 1428 LQELSSLI 1435
>XP_005268555
          Length = 1524

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    MQEISSLV 8
            +QE+SSL+
Sbjct: 1466 LQELSSLI 1473
>XP_005268554
          Length = 1531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    MQEISSLV 8
            +QE+SSL+
Sbjct: 1473 LQELSSLI 1480
>NP_001025190
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QEISSLVN 9
           +E+S+LVN
Sbjct: 164 EEVSNLVN 171
>NP_689995
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QEISSLVN 9
           +E+S+LVN
Sbjct: 164 EEVSNLVN 171
>NP_000490
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QEISSLVN 9
           QE+ SLVN
Sbjct: 212 QELLSLVN 219
>NP_056040
          Length = 3088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>NP_001234926
          Length = 1438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 549 LQEISSL 555
>NP_002947
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 538 LQEISSL 544
>NP_937883
          Length = 1392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 503 LQEISSL 509
>XP_005254242
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QEISSLVN 9
           QE+ SLVN
Sbjct: 212 QELLSLVN 219
>XP_006719618
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 503 LQEISSL 509
>XP_006719617
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 549 LQEISSL 555
>XP_006719616
          Length = 1405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 514 LQEISSL 520
>XP_006719615
          Length = 1429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 538 LQEISSL 544
>XP_006719614
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 549 LQEISSL 555
>XP_005253652
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 549 LQEISSL 555
>XP_005253651
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 549 LQEISSL 555
>XP_005253650
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   MQEISSL 7
           +QEISSL
Sbjct: 549 LQEISSL 555
>XP_005251811
          Length = 3060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251810
          Length = 3062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251809
          Length = 3063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251808
          Length = 3075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251807
          Length = 3088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251805
          Length = 3090

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251803
          Length = 3091

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717050
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_005251802
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717049
          Length = 3100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717048
          Length = 3101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717047
          Length = 3101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717046
          Length = 3103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
>XP_006717045
          Length = 3104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QEISSLV 8
            QE+SSLV
Sbjct: 1363 QELSSLV 1369
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.118    0.261 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 378,327
Number of extensions: 646
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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