Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           20     299
NP_036462                                                              20     299
NP_001243397                                                           20     299
XP_005269721                                                           20     299
NP_001092882                                                           18    1482
NP_006757                                                              18    1482
NP_001092883                                                           18    1482
XP_005273706                                                           18    1482
NP_001271230                                                           17    4312
NP_001271231                                                           17    4312
NP_061155                                                              17    4312
NP_060528                                                              17    4312
NP_001193457                                                           17    4312
XP_005269995                                                           17    4312
XP_006715810                                                           17    4312
XP_006715809                                                           17    4312
NP_002567                                                              16    7355
NP_001122092                                                           16    7355
NP_006097                                                              16    7355
NP_001269028                                                           16    7355
NP_001269026                                                           16    7355
NP_001269027                                                           16    7355
NP_061869                                                              16    7355
NP_001136112                                                           16    7355
NP_073150                                                              16    7355
XP_006722063                                                           16    7355
XP_006722062                                                           16    7355
XP_006722061                                                           16    7355
XP_006722060                                                           16    7355
XP_005257605                                                           16    7355
XP_005257604                                                           16    7355
XP_006722059                                                           16    7355
XP_006718639                                                           16    7355
XP_006718638                                                           16    7355
XP_006718637                                                           16    7355
XP_006718636                                                           16    7355
XP_005274082                                                           16    7355
XP_006718635                                                           16    7355
NP_006552                                                              15    9605
NP_001020248                                                           15    9605
NP_065816                                                              15    9605
NP_079461                                                              15    9605
NP_068708                                                              15    9605
NP_078917                                                              15    9605
XP_005257260                                                           15    9605
XP_005257258                                                           15    9605
XP_006721872                                                           15    9605
XP_006721871                                                           15    9605
XP_006721870                                                           15    9605
XP_006721869                                                           15    9605
XP_005252411                                                           15    9605
XP_006717433                                                           15    9605
XP_006717432                                                           15    9605
XP_006717431                                                           15    9605
XP_006717430                                                           15    9605
XP_005252408                                                           15    9605
XP_005252406                                                           15    9605
XP_005252405                                                           15    9605
XP_006717429                                                           15    9605
XP_006717428                                                           15    9605
XP_005267204                                                           15    9605
XP_006710573                                                           15    9605
XP_006710572                                                           15    9605
XP_006710571                                                           15    9605
XP_006710570                                                           15    9605
XP_006710569                                                           15    9605
XP_006710568                                                           15    9605
XP_006710567                                                           15    9605
XP_006710566                                                           15    9605
XP_005245859                                                           15    9605
NP_060882                                                              15    9605
>NP_001243398
          Length = 1781

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNTSNAMNG 9
            MNT NAMNG
Sbjct: 1694 MNTLNAMNG 1702
>NP_036462
          Length = 2073

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNTSNAMNG 9
            MNT NAMNG
Sbjct: 1986 MNTLNAMNG 1994
>NP_001243397
          Length = 1890

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNTSNAMNG 9
            MNT NAMNG
Sbjct: 1803 MNTLNAMNG 1811
>XP_005269721
          Length = 2073

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNTSNAMNG 9
            MNT NAMNG
Sbjct: 1986 MNTLNAMNG 1994
>NP_001092882
          Length = 2004

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    MNTSNAMN 8
            MNT NAMN
Sbjct: 1916 MNTLNAMN 1923
>NP_006757
          Length = 2004

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    MNTSNAMN 8
            MNT NAMN
Sbjct: 1916 MNTLNAMN 1923
>NP_001092883
          Length = 2004

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    MNTSNAMN 8
            MNT NAMN
Sbjct: 1916 MNTLNAMN 1923
>XP_005273706
          Length = 1997

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    MNTSNAMN 8
            MNT NAMN
Sbjct: 1909 MNTLNAMN 1916
>NP_001271230
          Length = 1087

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NTSNAMNG 9
           +TSN++NG
Sbjct: 813 STSNSLNG 820
>NP_001271231
          Length = 1086

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NTSNAMNG 9
           +TSN++NG
Sbjct: 812 STSNSLNG 819
>NP_061155
          Length = 1124

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NTSNAMNG 9
           +TSN++NG
Sbjct: 850 STSNSLNG 857
>NP_060528
          Length = 661

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNTSNAMNG 9
           +NT+NA +G
Sbjct: 133 LNTNNAFSG 141
>NP_001193457
          Length = 645

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNTSNAMNG 9
           +NT+NA +G
Sbjct: 133 LNTNNAFSG 141
>XP_005269995
          Length = 620

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MNTSNAMNG 9
           +NT+NA +G
Sbjct: 133 LNTNNAFSG 141
>XP_006715810
          Length = 1105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NTSNAMNG 9
           +TSN++NG
Sbjct: 813 STSNSLNG 820
>XP_006715809
          Length = 1142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NTSNAMNG 9
           +TSN++NG
Sbjct: 850 STSNSLNG 857
>NP_002567
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSNAMN 8
           N+SNA+N
Sbjct: 154 NSSNALN 160
>NP_001122092
          Length = 553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSNAMN 8
           N+SNA+N
Sbjct: 154 NSSNALN 160
>NP_006097
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MNTSNAMN 8
           MN+++AMN
Sbjct: 225 MNSASAMN 232
>NP_001269028
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MNTSNAMN 8
           MN+++AMN
Sbjct: 225 MNSASAMN 232
>NP_001269026
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MNTSNAMN 8
           MN+++AMN
Sbjct: 225 MNSASAMN 232
>NP_001269027
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MNTSNAMN 8
           MN+++AMN
Sbjct: 225 MNSASAMN 232
>NP_061869
          Length = 1690

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 334 STSNGVNG 341
>NP_001136112
          Length = 1726

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 334 STSNGVNG 341
>NP_073150
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TSNAMNG 9
           +SN+MNG
Sbjct: 475 SSNSMNG 481
>XP_006722063
          Length = 1923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 570 STSNGVNG 577
>XP_006722062
          Length = 1866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 570 STSNGVNG 577
>XP_006722061
          Length = 1913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 570 STSNGVNG 577
>XP_006722060
          Length = 1915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 570 STSNGVNG 577
>XP_005257605
          Length = 1926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 570 STSNGVNG 577
>XP_005257604
          Length = 1962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 570 STSNGVNG 577
>XP_006722059
          Length = 1965

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NTSNAMNG 9
           +TSN +NG
Sbjct: 570 STSNGVNG 577
>XP_006718639
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSNAMN 8
           N+SNA+N
Sbjct: 154 NSSNALN 160
>XP_006718638
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSNAMN 8
           N+SNA+N
Sbjct: 154 NSSNALN 160
>XP_006718637
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSNAMN 8
           N+SNA+N
Sbjct: 154 NSSNALN 160
>XP_006718636
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSNAMN 8
           N+SNA+N
Sbjct: 154 NSSNALN 160
>XP_005274082
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSNAMN 8
           N+SNA+N
Sbjct: 154 NSSNALN 160
>XP_006718635
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NTSNAMN 8
           N+SNA+N
Sbjct: 216 NSSNALN 222
>NP_006552
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 28 TANKMNG 34
>NP_001020248
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 21 TANKMNG 27
>NP_065816
          Length = 5183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4530 MNTLNVMLG 4538
>NP_079461
          Length = 1990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TSNAMNG 9
            T+NA NG
Sbjct: 1906 TNNAQNG 1912
>NP_068708
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSNAMNG 9
           N SN+ NG
Sbjct: 114 NNSNSSNG 121
>NP_078917
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSNAMNG 9
           NT N +NG
Sbjct: 372 NTRNRING 379
>XP_005257260
          Length = 1990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TSNAMNG 9
            T+NA NG
Sbjct: 1906 TNNAQNG 1912
>XP_005257258
          Length = 2000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TSNAMNG 9
            T+NA NG
Sbjct: 1916 TNNAQNG 1922
>XP_006721872
          Length = 2037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TSNAMNG 9
            T+NA NG
Sbjct: 1953 TNNAQNG 1959
>XP_006721871
          Length = 2037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TSNAMNG 9
            T+NA NG
Sbjct: 1953 TNNAQNG 1959
>XP_006721870
          Length = 2064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TSNAMNG 9
            T+NA NG
Sbjct: 1980 TNNAQNG 1986
>XP_006721869
          Length = 2074

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    TSNAMNG 9
            T+NA NG
Sbjct: 1990 TNNAQNG 1996
>XP_005252411
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 21 TANKMNG 27
>XP_006717433
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 21 TANKMNG 27
>XP_006717432
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 28 TANKMNG 34
>XP_006717431
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 33 TANKMNG 39
>XP_006717430
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 40 TANKMNG 46
>XP_005252408
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 52 TANKMNG 58
>XP_005252406
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 52 TANKMNG 58
>XP_005252405
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 52 TANKMNG 58
>XP_006717429
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 52 TANKMNG 58
>XP_006717428
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TSNAMNG 9
          T+N MNG
Sbjct: 52 TANKMNG 58
>XP_005267204
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSNAMNG 9
           NT N +NG
Sbjct: 372 NTRNRING 379
>XP_006710573
          Length = 5177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4524 MNTLNVMLG 4532
>XP_006710572
          Length = 5188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4535 MNTLNVMLG 4543
>XP_006710571
          Length = 5194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4541 MNTLNVMLG 4549
>XP_006710570
          Length = 5195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4542 MNTLNVMLG 4550
>XP_006710569
          Length = 5212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4559 MNTLNVMLG 4567
>XP_006710568
          Length = 5221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4568 MNTLNVMLG 4576
>XP_006710567
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4569 MNTLNVMLG 4577
>XP_006710566
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4569 MNTLNVMLG 4577
>XP_005245859
          Length = 5223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    MNTSNAMNG 9
            MNT N M G
Sbjct: 4570 MNTLNVMLG 4578
>NP_060882
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NTSNAMNG 9
           N SN+ NG
Sbjct: 114 NNSNSSNG 121
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.105    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 386,893
Number of extensions: 605
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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