Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           20     390
NP_036462                                                              20     390
NP_001243397                                                           20     390
NP_001092882                                                           20     390
NP_006757                                                              20     390
NP_001092883                                                           20     390
XP_005269721                                                           20     390
XP_005273706                                                           20     390
NP_055840                                                              18    1935
XP_006711931                                                           18    1935
XP_006711930                                                           18    1935
XP_006711929                                                           18    1935
XP_006711928                                                           18    1935
XP_006711927                                                           18    1935
XP_006711926                                                           18    1935
XP_006711925                                                           18    1935
NP_003292                                                              16    5631
NP_115954                                                              16    7355
NP_001245308                                                           16    7355
NP_078966                                                              16    7355
NP_659001                                                              16    7355
NP_001154178                                                           16    7355
NP_000258                                                              16    7355
NP_001035957                                                           16    7355
NP_003834                                                              16    7355
NP_775821                                                              16    7355
XP_006721990                                                           16    7355
XP_006721989                                                           16    7355
XP_005258041                                                           16    7355
XP_006721988                                                           16    7355
XP_006721987                                                           16    7355
XP_006721986                                                           16    7355
XP_005258040                                                           16    7355
XP_006721985                                                           16    7355
XP_006719949                                                           16    7355
XP_006719948                                                           16    7355
XP_005266635                                                           16    7355
XP_006719947                                                           16    7355
XP_006719946                                                           16    7355
XP_006719945                                                           16    7355
XP_005251455                                                           16    7355
XP_005251456                                                           16    7355
XP_005251454                                                           16    7355
XP_005265657                                                           16    7355
XP_005265656                                                           16    7355
XP_005265655                                                           16    7355
XP_006713484                                                           16    7355
NP_055178                                                              15    9605
NP_001264984                                                           15    9605
NP_001269701                                                           15    9605
NP_061887                                                              15    9605
NP_001269706                                                           15    9605
NP_001269708                                                           15    9605
NP_001269705                                                           15    9605
NP_001131076                                                           15    9605
NP_001106853                                                           15    9605
XP_005266395                                                           15    9605
XP_006717495                                                           15    9605
XP_006717494                                                           15    9605
XP_006717493                                                           15    9605
XP_006717492                                                           15    9605
XP_006717490                                                           15    9605
XP_006717489                                                           15    9605
XP_006717488                                                           15    9605
XP_006717487                                                           15    9605
XP_006717486                                                           15    9605
XP_006712889                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNMNTSNAM 9
            MNMNT NAM
Sbjct: 1692 MNMNTLNAM 1700
>NP_036462
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNMNTSNAM 9
            MNMNT NAM
Sbjct: 1984 MNMNTLNAM 1992
>NP_001243397
          Length = 1890

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNMNTSNAM 9
            MNMNT NAM
Sbjct: 1801 MNMNTLNAM 1809
>NP_001092882
          Length = 2004

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNMNTSNAM 9
            MNMNT NAM
Sbjct: 1914 MNMNTLNAM 1922
>NP_006757
          Length = 2004

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNMNTSNAM 9
            MNMNT NAM
Sbjct: 1914 MNMNTLNAM 1922
>NP_001092883
          Length = 2004

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNMNTSNAM 9
            MNMNT NAM
Sbjct: 1914 MNMNTLNAM 1922
>XP_005269721
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNMNTSNAM 9
            MNMNT NAM
Sbjct: 1984 MNMNTLNAM 1992
>XP_005273706
          Length = 1997

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MNMNTSNAM 9
            MNMNT NAM
Sbjct: 1907 MNMNTLNAM 1915
>NP_055840
          Length = 1184

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMNTSNAM 9
           MN NTSN++
Sbjct: 225 MNSNTSNSL 233
>XP_006711931
          Length = 1162

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMNTSNAM 9
           MN NTSN++
Sbjct: 225 MNSNTSNSL 233
>XP_006711930
          Length = 1186

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMNTSNAM 9
           MN NTSN++
Sbjct: 225 MNSNTSNSL 233
>XP_006711929
          Length = 1186

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMNTSNAM 9
           MN NTSN++
Sbjct: 225 MNSNTSNSL 233
>XP_006711928
          Length = 1188

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMNTSNAM 9
           MN NTSN++
Sbjct: 225 MNSNTSNSL 233
>XP_006711927
          Length = 1207

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMNTSNAM 9
           MN NTSN++
Sbjct: 225 MNSNTSNSL 233
>XP_006711926
          Length = 1207

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMNTSNAM 9
           MN NTSN++
Sbjct: 225 MNSNTSNSL 233
>XP_006711925
          Length = 1209

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMNTSNAM 9
           MN NTSN++
Sbjct: 225 MNSNTSNSL 233
>NP_003292
          Length = 398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MNMNTSN 7
           +N+NTSN
Sbjct: 245 LNVNTSN 251
>NP_115954
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NMNTSN 7
           N+NTSN
Sbjct: 156 NLNTSN 161
>NP_001245308
          Length = 1131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MNMNTSNA 8
            ++MNT NA
Sbjct: 1090 LSMNTENA 1097
>NP_078966
          Length = 14507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            NM T+N+M
Sbjct: 6015 NMGTTNSM 6022
>NP_659001
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 139 LNANTSNTI 147
>NP_001154178
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 139 LNANTSNTI 147
>NP_000258
          Length = 2818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2754 NLNLSNSM 2761
>NP_001035957
          Length = 2839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2775 NLNLSNSM 2782
>NP_003834
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 139 LNANTSNTI 147
>NP_775821
          Length = 1326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1 MNMNTSN 7
         MN+NTS+
Sbjct: 1 MNLNTSS 7
>XP_006721990
          Length = 2823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2785 NLNLSNSM 2792
>XP_006721989
          Length = 2823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2785 NLNLSNSM 2792
>XP_005258041
          Length = 2836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2754 NLNLSNSM 2761
>XP_006721988
          Length = 2846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2764 NLNLSNSM 2771
>XP_006721987
          Length = 2849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2785 NLNLSNSM 2792
>XP_006721986
          Length = 2854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2772 NLNLSNSM 2779
>XP_005258040
          Length = 2857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2775 NLNLSNSM 2782
>XP_006721985
          Length = 2867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NMNTSNAM 9
            N+N SN+M
Sbjct: 2785 NLNLSNSM 2792
>XP_006719949
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 139 LNANTSNTI 147
>XP_006719948
          Length = 648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 139 LNANTSNTI 147
>XP_005266635
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 116 LNANTSNTI 124
>XP_006719947
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 139 LNANTSNTI 147
>XP_006719946
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 139 LNANTSNTI 147
>XP_006719945
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           +N NTSN +
Sbjct: 139 LNANTSNTI 147
>XP_005251455
          Length = 1334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1 MNMNTSN 7
         MN+NTS+
Sbjct: 1 MNLNTSS 7
>XP_005251456
          Length = 1334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1 MNMNTSN 7
         MN+NTS+
Sbjct: 1 MNLNTSS 7
>XP_005251454
          Length = 1334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1 MNMNTSN 7
         MN+NTS+
Sbjct: 1 MNLNTSS 7
>XP_005265657
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MNMNTSNA 8
            ++MNT NA
Sbjct: 1072 LSMNTENA 1079
>XP_005265656
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MNMNTSNA 8
            ++MNT NA
Sbjct: 1077 LSMNTENA 1084
>XP_005265655
          Length = 1126

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MNMNTSNA 8
            ++MNT NA
Sbjct: 1085 LSMNTENA 1092
>XP_006713484
          Length = 1255

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MNMNTSNA 8
            ++MNT NA
Sbjct: 1214 LSMNTENA 1221
>NP_055178
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MNMNTSN 7
            +NM+TSN
Sbjct: 3015 INMSTSN 3021
>NP_001264984
          Length = 4432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MNMNTSN 7
            +NM+TSN
Sbjct: 2868 INMSTSN 2874
>NP_001269701
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           ++MNT N M
Sbjct: 447 VSMNTDNLM 455
>NP_061887
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           ++MNT N M
Sbjct: 409 VSMNTDNLM 417
>NP_001269706
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           ++MNT N M
Sbjct: 270 VSMNTDNLM 278
>NP_001269708
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           ++MNT N M
Sbjct: 270 VSMNTDNLM 278
>NP_001269705
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           ++MNT N M
Sbjct: 198 VSMNTDNLM 206
>NP_001131076
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMNTSNAM 9
           ++MNT N M
Sbjct: 353 VSMNTDNLM 361
>NP_001106853
          Length = 2093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NMNTSNA 8
            ++NTSNA
Sbjct: 2045 SLNTSNA 2051
>XP_005266395
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MNMNTSN 7
            +NM+TSN
Sbjct: 3024 INMSTSN 3030
>XP_006717495
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 774 MNRNTTN 780
>XP_006717494
          Length = 1571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 273 MNRNTTN 279
>XP_006717493
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 312 MNRNTTN 318
>XP_006717492
          Length = 1635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 774 MNRNTTN 780
>XP_006717490
          Length = 1791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 493 MNRNTTN 499
>XP_006717489
          Length = 1945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 774 MNRNTTN 780
>XP_006717488
          Length = 2031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 774 MNRNTTN 780
>XP_006717487
          Length = 2071

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 774 MNRNTTN 780
>XP_006717486
          Length = 2072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   MNMNTSN 7
           MN NT+N
Sbjct: 774 MNRNTTN 780
>XP_006712889
          Length = 2069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NMNTSNA 8
            ++NTSNA
Sbjct: 2021 SLNTSNA 2027
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305   0.0997    0.251 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 351,354
Number of extensions: 526
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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