Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     299
NP_055571                                                              17    3301
NP_001008938                                                           17    3301
NP_001037835                                                           17    4312
NP_005877                                                              17    4312
XP_006721186                                                           17    4312
XP_005255829                                                           17    4312
XP_006721185                                                           17    4312
XP_006721184                                                           17    4312
NP_004534                                                              16    7355
NP_001258137                                                           16    7355
NP_001157980                                                           16    7355
NP_001157979                                                           16    7355
XP_005246674                                                           16    7355
XP_005246673                                                           16    7355
XP_005246672                                                           16    7355
XP_005246670                                                           16    7355
XP_005246669                                                           16    7355
XP_005246668                                                           16    7355
XP_005246667                                                           16    7355
XP_005246665                                                           16    7355
XP_006712605                                                           16    7355
XP_006712604                                                           16    7355
XP_005246663                                                           16    7355
XP_005246660                                                           16    7355
XP_005246661                                                           16    7355
XP_005246659                                                           16    7355
XP_005246658                                                           16    7355
XP_005246657                                                           16    7355
XP_005246656                                                           16    7355
XP_005246655                                                           16    7355
XP_005246654                                                           16    7355
XP_005246653                                                           16    7355
XP_005246652                                                           16    7355
XP_005246649                                                           16    7355
XP_005246651                                                           16    7355
XP_005246650                                                           16    7355
XP_005246648                                                           16    7355
XP_005246647                                                           16    7355
NP_000375                                                              15    9605
NP_001158238                                                           15    9605
NP_078997                                                              15    9605
NP_001131074                                                           15    9605
NP_057039                                                              15    9605
NP_008816                                                              15    9605
NP_001254500                                                           15    9605
NP_001254501                                                           15    9605
NP_060891                                                              15    9605
XP_005256014                                                           15    9605
XP_006712091                                                           15    9605
XP_005264408                                                           15    9605
>NP_004295
          Length = 1620

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    MNMAFSQSN 9
            +NMAFSQSN
Sbjct: 1476 VNMAFSQSN 1484
>NP_055571
          Length = 1972

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMAFSQSN 9
           ++MAFSQ N
Sbjct: 720 VSMAFSQKN 728
>NP_001008938
          Length = 2032

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMAFSQSN 9
           ++MAFSQ N
Sbjct: 720 VSMAFSQKN 728
>NP_001037835
          Length = 326

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  MNMAFSQSN 9
          + MAFSQS+
Sbjct: 23 LGMAFSQSH 31
>NP_005877
          Length = 655

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMAFSQSN 9
           + +AFSQSN
Sbjct: 286 IGVAFSQSN 294
>XP_006721186
          Length = 658

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMAFSQSN 9
           + +AFSQSN
Sbjct: 286 IGVAFSQSN 294
>XP_005255829
          Length = 672

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMAFSQSN 9
           + +AFSQSN
Sbjct: 286 IGVAFSQSN 294
>XP_006721185
          Length = 675

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMAFSQSN 9
           + +AFSQSN
Sbjct: 286 IGVAFSQSN 294
>XP_006721184
          Length = 675

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   MNMAFSQSN 9
           + +AFSQSN
Sbjct: 286 IGVAFSQSN 294
>NP_004534
          Length = 6669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>NP_001258137
          Length = 8560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>NP_001157980
          Length = 8525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>NP_001157979
          Length = 8525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246674
          Length = 7553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246673
          Length = 8018

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246672
          Length = 8277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246670
          Length = 8282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246669
          Length = 8282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246668
          Length = 8308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246667
          Length = 8308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246665
          Length = 8339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_006712605
          Length = 8370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_006712604
          Length = 8370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246663
          Length = 8370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246660
          Length = 8370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246661
          Length = 8370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246659
          Length = 8401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246658
          Length = 8401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246657
          Length = 8432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246656
          Length = 8432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246655
          Length = 8463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246654
          Length = 8463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246653
          Length = 8463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246652
          Length = 8494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246649
          Length = 8494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246651
          Length = 8494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246650
          Length = 8494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246648
          Length = 8494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>XP_005246647
          Length = 8494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            MNM  +Q+N
Sbjct: 1976 MNMVLAQNN 1984
>NP_000375
          Length = 4563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    MNMAFSQSN 9
            M+M FS+ N
Sbjct: 1587 MDMTFSKQN 1595
>NP_001158238
          Length = 2789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NMAFSQSN 9
           N+A+SQS+
Sbjct: 688 NVAYSQSS 695
>NP_078997
          Length = 3616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    NMAFSQSN 9
            N+A+SQS+
Sbjct: 1599 NVAYSQSS 1606
>NP_001131074
          Length = 274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MNMAFSQSN 9
           MNM+FS  N
Sbjct: 241 MNMSFSFLN 249
>NP_057039
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MNMAFSQSN 9
           MNM+FS  N
Sbjct: 264 MNMSFSFLN 272
>NP_008816
          Length = 3703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    NMAFSQSN 9
            N+A+SQS+
Sbjct: 1602 NVAYSQSS 1609
>NP_001254500
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMAFSQSN 9
           MN+AF+  N
Sbjct: 863 MNIAFNDMN 871
>NP_001254501
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMAFSQSN 9
           MN+AF+  N
Sbjct: 403 MNIAFNDMN 411
>NP_060891
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MNMAFSQSN 9
           MN+AF+  N
Sbjct: 852 MNIAFNDMN 860
>XP_005256014
          Length = 3702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    NMAFSQSN 9
            N+A+SQS+
Sbjct: 1601 NVAYSQSS 1608
>XP_006712091
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MNMAFSQSN 9
           MNM+FS  N
Sbjct: 147 MNMSFSFLN 155
>XP_005264408
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MNMAFSQSN 9
           MNM+FS  N
Sbjct: 264 MNMSFSFLN 272
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.108    0.273 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 295,810
Number of extensions: 287
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package