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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115894                                                              17    2528
XP_005264828                                                           17    2528
NP_114161                                                              16    5631
XP_006713841                                                           16    5631
NP_004988                                                              16    7355
XP_005245254                                                           16    7355
XP_005245253                                                           16    7355
NP_620168                                                              15    9605
NP_057445                                                              15    9605
NP_001171473                                                           15    9605
XP_006722720                                                           15    9605
XP_006722719                                                           15    9605
XP_006722718                                                           15    9605
XP_006722717                                                           15    9605
XP_006711427                                                           15    9605
XP_005277457                                                           15    9605
XP_006711426                                                           15    9605

>NP_115894
          Length = 601

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LFIRSTQV 9
           LF+R+TQV
Sbjct: 536 LFVRATQV 543



>XP_005264828
          Length = 524

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LFIRSTQV 9
           LF+R+TQV
Sbjct: 459 LFVRATQV 466



>NP_114161
          Length = 569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FIRSTQV 9
           FIRSTQ+
Sbjct: 439 FIRSTQL 445



>XP_006713841
          Length = 540

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FIRSTQV 9
           FIRSTQ+
Sbjct: 439 FIRSTQL 445



>NP_004988
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   MLFIRSTQ 8
           +LFIRS Q
Sbjct: 230 ILFIRSAQ 237



>XP_005245254
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  MLFIRSTQ 8
          +LFIRS Q
Sbjct: 68 ILFIRSAQ 75



>XP_005245253
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   MLFIRSTQ 8
           +LFIRS Q
Sbjct: 230 ILFIRSAQ 237



>NP_620168
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MLFIRSTQ 8
           +LFIR+T+
Sbjct: 192 LLFIRATR 199



>NP_057445
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFIRSTQV 9
           +FIRST +
Sbjct: 159 VFIRSTNI 166



>NP_001171473
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MLFIRSTQ 8
           +LFIR+T+
Sbjct: 139 LLFIRATR 146



>XP_006722720
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MLFIRSTQ 8
           +LFIR+T+
Sbjct: 192 LLFIRATR 199



>XP_006722719
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MLFIRSTQ 8
           +LFIR+T+
Sbjct: 106 LLFIRATR 113



>XP_006722718
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MLFIRSTQ 8
           +LFIR+T+
Sbjct: 192 LLFIRATR 199



>XP_006722717
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MLFIRSTQ 8
           +LFIR+T+
Sbjct: 192 LLFIRATR 199



>XP_006711427
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFIRSTQV 9
           +FIRST +
Sbjct: 116 VFIRSTNI 123



>XP_005277457
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFIRSTQV 9
           +FIRST +
Sbjct: 159 VFIRSTNI 166



>XP_006711426
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFIRSTQV 9
           +FIRST +
Sbjct: 116 VFIRSTNI 123



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.347    0.144    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 290,325
Number of extensions: 364
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)