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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              18    1935
NP_001129225                                                           17    4312
NP_001129224                                                           17    4312
NP_009196                                                              17    4312
NP_056127                                                              16    5631
XP_006714407                                                           16    5631
XP_006714406                                                           16    5631
XP_006714405                                                           16    5631
XP_005263349                                                           16    5631
XP_005263348                                                           16    5631
XP_005263347                                                           16    5631
XP_005263346                                                           16    5631
XP_005263345                                                           16    5631
XP_005263344                                                           16    5631
XP_005263343                                                           16    5631
XP_005263342                                                           16    5631
XP_005263341                                                           16    5631
XP_005263340                                                           16    5631
XP_005263339                                                           16    5631
NP_009117                                                              16    7355
NP_877949                                                              16    7355
NP_000924                                                              16    7355
NP_001073005                                                           16    7355
XP_005260322                                                           16    7355
XP_005260321                                                           16    7355
XP_005260320                                                           16    7355
XP_006723758                                                           16    7355
XP_006723757                                                           16    7355
XP_006723756                                                           16    7355
XP_006723755                                                           16    7355
XP_006723754                                                           16    7355
XP_006723753                                                           16    7355
XP_005260319                                                           16    7355
XP_006723635                                                           16    7355
XP_006723633                                                           16    7355
NP_803235                                                              16    7355
NP_054749                                                              15    9605
NP_001078923                                                           15    9605

>NP_115927
          Length = 1321

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   MKKSLVTAE 9
           MKKS VTAE
Sbjct: 844 MKKSPVTAE 852



>NP_001129225
          Length = 601

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   KKSLVTA 8
           KKSLVTA
Sbjct: 280 KKSLVTA 286



>NP_001129224
          Length = 677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   KKSLVTA 8
           KKSLVTA
Sbjct: 323 KKSLVTA 329



>NP_009196
          Length = 644

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   KKSLVTA 8
           KKSLVTA
Sbjct: 323 KKSLVTA 329



>NP_056127
          Length = 5005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>XP_006714407
          Length = 5004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2761 KRSLVTSE 2768



>XP_006714406
          Length = 3680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>XP_006714405
          Length = 4103

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 1839 KRSLVTSE 1846



>XP_005263349
          Length = 4410

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2146 KRSLVTSE 2153



>XP_005263348
          Length = 4443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2179 KRSLVTSE 2186



>XP_005263347
          Length = 4640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>XP_005263346
          Length = 4983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2719 KRSLVTSE 2726



>XP_005263345
          Length = 4991

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>XP_005263344
          Length = 5005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>XP_005263343
          Length = 5009

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>XP_005263342
          Length = 5025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2761 KRSLVTSE 2768



>XP_005263341
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>XP_005263340
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>XP_005263339
          Length = 5026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    KKSLVTAE 9
            K+SLVT+E
Sbjct: 2762 KRSLVTSE 2769



>NP_009117
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1548 LKKQLVTLE 1556



>NP_877949
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MKKSLVTAE 9
           +KK LVT E
Sbjct: 535 VKKGLVTVE 543



>NP_000924
          Length = 1194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MKKSLVTAE 9
           +KK LVT E
Sbjct: 535 VKKGLVTVE 543



>NP_001073005
          Length = 158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KSLVTAE 9
           KS+VTAE
Sbjct: 136 KSIVTAE 142



>XP_005260322
          Length = 1810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MKKSLVTAE 9
           +KK LVT E
Sbjct: 916 LKKQLVTLE 924



>XP_005260321
          Length = 2365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1471 LKKQLVTLE 1479



>XP_005260320
          Length = 2370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1548 LKKQLVTLE 1556



>XP_006723758
          Length = 2386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1492 LKKQLVTLE 1500



>XP_006723757
          Length = 2404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1548 LKKQLVTLE 1556



>XP_006723756
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1548 LKKQLVTLE 1556



>XP_006723755
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1548 LKKQLVTLE 1556



>XP_006723754
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1548 LKKQLVTLE 1556



>XP_006723753
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1548 LKKQLVTLE 1556



>XP_005260319
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    MKKSLVTAE 9
            +KK LVT E
Sbjct: 1548 LKKQLVTLE 1556



>XP_006723635
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MKKSLVTAE 9
           +KK LVT E
Sbjct: 535 VKKGLVTVE 543



>XP_006723633
          Length = 1194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   MKKSLVTAE 9
           +KK LVT E
Sbjct: 535 VKKGLVTVE 543



>NP_803235
          Length = 130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KSLVTAE 9
           KS+VTAE
Sbjct: 108 KSIVTAE 114



>NP_054749
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MKKSLVTAE 9
           +KK+L T+E
Sbjct: 429 LKKALATSE 437



>NP_001078923
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MKKSLVTAE 9
           +KK+L T+E
Sbjct: 438 LKKALATSE 446



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.110    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 305,003
Number of extensions: 337
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)