Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              20     390
NP_001035957                                                           20     390
XP_005276506                                                           20     390
XP_006721991                                                           20     390
XP_006721990                                                           20     390
XP_006721989                                                           20     390
XP_005258041                                                           20     390
XP_006721988                                                           20     390
XP_006721987                                                           20     390
XP_006721986                                                           20     390
XP_005258040                                                           20     390
XP_006721985                                                           20     390
XP_006720412                                                           20     390
NP_079027                                                              17    4312
NP_001026890                                                           17    4312
XP_005263279                                                           17    4312
NP_003282                                                              16    5631
XP_005254129                                                           16    5631
XP_005254128                                                           16    5631
XP_005254127                                                           16    5631
NP_689916                                                              15    9605
NP_001269973                                                           15    9605
NP_065076                                                              15    9605
NP_060124                                                              15    9605
NP_055805                                                              15    9605
NP_001273903                                                           15    9605
NP_001269972                                                           15    9605
NP_003789                                                              15    9605
NP_919277                                                              15    9605
NP_001180236                                                           15    9605
XP_005276330                                                           15    9605
XP_006723662                                                           15    9605
XP_005260825                                                           15    9605
XP_006723661                                                           15    9605
XP_005267555                                                           15    9605
XP_006720166                                                           15    9605
XP_005267550                                                           15    9605
XP_005267549                                                           15    9605
XP_005267548                                                           15    9605
XP_006720165                                                           15    9605
XP_006720164                                                           15    9605
XP_006720163                                                           15    9605
XP_006720162                                                           15    9605
XP_006720161                                                           15    9605
XP_005252348                                                           15    9605
XP_006715953                                                           15    9605
XP_006715952                                                           15    9605
XP_005250250                                                           15    9605
XP_006715951                                                           15    9605
XP_005250248                                                           15    9605
XP_005249570                                                           15    9605
>NP_000258
          Length = 2818

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1035 MKFRNKMVE 1043
>NP_001035957
          Length = 2839

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1035 MKFRNKMVE 1043
>XP_005276506
          Length = 151

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  MKFSNKMVE 9
          MKF NKMVE
Sbjct: 68 MKFRNKMVE 76
>XP_006721991
          Length = 1632

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1045 MKFRNKMVE 1053
>XP_006721990
          Length = 2823

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1045 MKFRNKMVE 1053
>XP_006721989
          Length = 2823

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1045 MKFRNKMVE 1053
>XP_005258041
          Length = 2836

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1035 MKFRNKMVE 1043
>XP_006721988
          Length = 2846

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1045 MKFRNKMVE 1053
>XP_006721987
          Length = 2849

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1045 MKFRNKMVE 1053
>XP_006721986
          Length = 2854

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1032 MKFRNKMVE 1040
>XP_005258040
          Length = 2857

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1035 MKFRNKMVE 1043
>XP_006721985
          Length = 2867

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            MKF NKMVE
Sbjct: 1045 MKFRNKMVE 1053
>XP_006720412
          Length = 128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  MKFSNKMVE 9
          MKF NKMVE
Sbjct: 45 MKFRNKMVE 53
>NP_079027
          Length = 546

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KFSNKMVE 9
           KFS K+VE
Sbjct: 217 KFSEKLVE 224
>NP_001026890
          Length = 633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KFSNKMVE 9
           KFS K+VE
Sbjct: 304 KFSEKLVE 311
>XP_005263279
          Length = 633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KFSNKMVE 9
           KFS K+VE
Sbjct: 304 KFSEKLVE 311
>NP_003282
          Length = 1249

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            +KF+ K+VE
Sbjct: 1199 LKFATKLVE 1207
>XP_005254129
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            +KF+ K+VE
Sbjct: 1212 LKFATKLVE 1220
>XP_005254128
          Length = 1291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            +KF+ K+VE
Sbjct: 1241 LKFATKLVE 1249
>XP_005254127
          Length = 1304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    MKFSNKMVE 9
            +KF+ K+VE
Sbjct: 1254 LKFATKLVE 1262
>NP_689916
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MKFSNKM 7
           MKFSN++
Sbjct: 215 MKFSNEV 221
>NP_001269973
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1372 LKFTNKTV 1379
>NP_065076
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF NK+V
Sbjct: 1193 LKFPNKIV 1200
>NP_060124
          Length = 1589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MKFSNKM 7
           MKFSN++
Sbjct: 213 MKFSNEV 219
>NP_055805
          Length = 2036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1325 LKFTNKTV 1332
>NP_001273903
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KFSNKMVE 9
           +F N+MVE
Sbjct: 196 QFGNEMVE 203
>NP_001269972
          Length = 2049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1338 LKFTNKTV 1345
>NP_003789
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KFSNKMVE 9
           +F N+MVE
Sbjct: 196 QFGNEMVE 203
>NP_919277
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1325 LKFTNKTV 1332
>NP_001180236
          Length = 1589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MKFSNKM 7
           MKFSN++
Sbjct: 213 MKFSNEV 219
>XP_005276330
          Length = 111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  MKFSNKMVE 9
          +KF NK+ E
Sbjct: 58 IKFPNKLYE 66
>XP_006723662
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF NK+V
Sbjct: 1240 LKFPNKIV 1247
>XP_005260825
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF NK+V
Sbjct: 1193 LKFPNKIV 1200
>XP_006723661
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF NK+V
Sbjct: 1240 LKFPNKIV 1247
>XP_005267555
          Length = 1325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MKFSNKMV 8
           +KF+NK V
Sbjct: 566 LKFTNKTV 573
>XP_006720166
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1372 LKFTNKTV 1379
>XP_005267550
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1325 LKFTNKTV 1332
>XP_005267549
          Length = 2130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1372 LKFTNKTV 1379
>XP_005267548
          Length = 2131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1372 LKFTNKTV 1379
>XP_006720165
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1831 LKFTNKTV 1838
>XP_006720164
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1831 LKFTNKTV 1838
>XP_006720163
          Length = 2543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1784 LKFTNKTV 1791
>XP_006720162
          Length = 2589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1831 LKFTNKTV 1838
>XP_006720161
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    MKFSNKMV 8
            +KF+NK V
Sbjct: 1831 LKFTNKTV 1838
>XP_005252348
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KFSNKMVE 9
           +F N+MVE
Sbjct: 196 QFGNEMVE 203
>XP_006715953
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MKFSNKM 7
           MKFSN++
Sbjct: 215 MKFSNEV 221
>XP_006715952
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MKFSNKM 7
           MKFSN++
Sbjct: 215 MKFSNEV 221
>XP_005250250
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MKFSNKM 7
           MKFSN++
Sbjct: 215 MKFSNEV 221
>XP_006715951
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MKFSNKM 7
           MKFSN++
Sbjct: 215 MKFSNEV 221
>XP_005250248
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   MKFSNKM 7
           MKFSN++
Sbjct: 215 MKFSNEV 221
>XP_005249570
          Length = 111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  MKFSNKMVE 9
          +KF NK+ E
Sbjct: 58 IKFPNKLYE 66
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.122    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 367,139
Number of extensions: 374
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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