Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           22     134
NP_858045                                                              22     134
NP_006525                                                              22     134
NP_001167559                                                           22     134
NP_001013011                                                           17    3301
NP_001186491                                                           17    4312
NP_003551                                                              17    4312
NP_001004426                                                           17    4312
NP_689548                                                              17    4312
NP_573439                                                              17    4312
NP_573438                                                              17    4312
NP_001181930                                                           17    4312
NP_005695                                                              17    4312
XP_005261828                                                           17    4312
XP_006724395                                                           17    4312
XP_005261823                                                           17    4312
XP_005261822                                                           17    4312
XP_005261821                                                           17    4312
XP_005254217                                                           17    4312
XP_006710336                                                           17    4312
XP_006710335                                                           17    4312
XP_006710334                                                           17    4312
XP_006710333                                                           17    4312
XP_006710332                                                           17    4312
NP_001164100                                                           16    5631
NP_001252541                                                           16    5631
NP_057368                                                              16    5631
NP_057245                                                              16    5631
NP_000940                                                              16    7355
NP_001191247                                                           16    7355
NP_001191245                                                           16    7355
NP_001191246                                                           16    7355
NP_001191244                                                           16    7355
NP_001129248                                                           16    7355
NP_054726                                                              16    7355
NP_001268369                                                           16    7355
NP_068759                                                              16    7355
NP_001229852                                                           16    7355
NP_057175                                                              16    7355
NP_001037770                                                           16    7355
XP_005261682                                                           16    7355
XP_006724323                                                           16    7355
XP_005251893                                                           16    7355
XP_005251892                                                           16    7355
XP_006714547                                                           16    7355
NP_954635                                                              15    9605
NP_000679                                                              15    9605
NP_001138295                                                           15    9605
NP_005839                                                              15    9605
NP_001273052                                                           15    9605
NP_001273054                                                           15    9605
NP_005826                                                              15    9605
NP_060063                                                              15    9605
NP_942595                                                              15    9605
XP_005254179                                                           15    9605
XP_005254178                                                           15    9605
XP_006720435                                                           15    9605
XP_005254177                                                           15    9605
XP_006720434                                                           15    9605
XP_005254176                                                           15    9605
XP_006715015                                                           15    9605
XP_006715014                                                           15    9605
XP_006715013                                                           15    9605
XP_006715012                                                           15    9605
XP_005248841                                                           15    9605
XP_005263174                                                           15    9605
XP_005265002                                                           15    9605
XP_005265001                                                           15    9605
NP_054735                                                              15    9605
>NP_001167558
          Length = 1423

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    MINQMNQQG 9
            M+NQMNQQG
Sbjct: 1138 MMNQMNQQG 1146
>NP_858045
          Length = 1424

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    MINQMNQQG 9
            M+NQMNQQG
Sbjct: 1138 MMNQMNQQG 1146
>NP_006525
          Length = 1420

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    MINQMNQQG 9
            M+NQMNQQG
Sbjct: 1138 MMNQMNQQG 1146
>NP_001167559
          Length = 1415

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    MINQMNQQG 9
            M+NQMNQQG
Sbjct: 1133 MMNQMNQQG 1141
>NP_001013011
          Length = 239

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   NQMNQQG 9
           NQM QQG
Sbjct: 163 NQMTQQG 169
>NP_001186491
          Length = 752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INQMNQQG 9
           +NQ+N QG
Sbjct: 213 LNQVNNQG 220
>NP_003551
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INQMNQQG 9
           +NQ+N QG
Sbjct: 213 LNQVNNQG 220
>NP_001004426
          Length = 752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INQMNQQG 9
           +NQ+N QG
Sbjct: 213 LNQVNNQG 220
>NP_689548
          Length = 531

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MINQMNQQG 9
           + NQ NQ+G
Sbjct: 484 LFNQKNQEG 492
>NP_573439
          Length = 1436

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1265 MLNQLNQ 1271
>NP_573438
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1271 MLNQLNQ 1277
>NP_001181930
          Length = 1433

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1262 MLNQLNQ 1268
>NP_005695
          Length = 1446

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1275 MLNQLNQ 1281
>XP_005261828
          Length = 467

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INQMNQQG 9
           +NQ+N QG
Sbjct: 213 LNQVNNQG 220
>XP_006724395
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INQMNQQG 9
           +NQ+N QG
Sbjct: 213 LNQVNNQG 220
>XP_005261823
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INQMNQQG 9
           +NQ+N QG
Sbjct: 213 LNQVNNQG 220
>XP_005261822
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INQMNQQG 9
           +NQ+N QG
Sbjct: 213 LNQVNNQG 220
>XP_005261821
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INQMNQQG 9
           +NQ+N QG
Sbjct: 213 LNQVNNQG 220
>XP_005254217
          Length = 347

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   MINQMNQQG 9
           + NQ NQ+G
Sbjct: 300 LFNQKNQEG 308
>XP_006710336
          Length = 1177

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1006 MLNQLNQ 1012
>XP_006710335
          Length = 1370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1199 MLNQLNQ 1205
>XP_006710334
          Length = 1292

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1121 MLNQLNQ 1127
>XP_006710333
          Length = 1439

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1268 MLNQLNQ 1274
>XP_006710332
          Length = 1442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    MINQMNQ 7
            M+NQ+NQ
Sbjct: 1271 MLNQLNQ 1277
>NP_001164100
          Length = 2581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  INQMNQQG 9
          ++QMNQ G
Sbjct: 46 LDQMNQDG 53
>NP_001252541
          Length = 2371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    INQMNQQG 9
            + QM+QQG
Sbjct: 1875 VGQMHQQG 1882
>NP_057368
          Length = 2376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    INQMNQQG 9
            + QM+QQG
Sbjct: 1880 VGQMHQQG 1887
>NP_057245
          Length = 340

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NQMNQQG 9
           N MNQ+G
Sbjct: 291 NHMNQEG 297
>NP_000940
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MINQMNQQG 9
           M+N  NQ G
Sbjct: 102 MVNATNQMG 110
>NP_001191247
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MINQMNQQG 9
           M+N  NQ G
Sbjct: 102 MVNATNQMG 110
>NP_001191245
          Length = 376

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MINQMNQQG 9
           M+N  NQ G
Sbjct: 102 MVNATNQMG 110
>NP_001191246
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MINQMNQQG 9
           M+N  NQ G
Sbjct: 102 MVNATNQMG 110
>NP_001191244
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MINQMNQQG 9
           M+N  NQ G
Sbjct: 102 MVNATNQMG 110
>NP_001129248
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  INQMNQQG 9
          +NQ  QQG
Sbjct: 23 LNQQRQQG 30
>NP_054726
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  INQMNQQG 9
          +NQ  QQG
Sbjct: 23 LNQQRQQG 30
>NP_001268369
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   INQMNQQ 8
           ++QMNQQ
Sbjct: 411 LSQMNQQ 417
>NP_068759
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   INQMNQQ 8
           ++QMNQQ
Sbjct: 394 LSQMNQQ 400
>NP_001229852
          Length = 516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MINQMNQQ 8
           MIN+ N+Q
Sbjct: 311 MINKQNEQ 318
>NP_057175
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MINQMNQQ 8
           MIN+ N+Q
Sbjct: 359 MINKQNEQ 366
>NP_001037770
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   INQMNQQ 8
           ++QMNQQ
Sbjct: 421 LSQMNQQ 427
>XP_005261682
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MINQMNQQ 8
           MIN+ N+Q
Sbjct: 261 MINKQNEQ 268
>XP_006724323
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   MINQMNQQ 8
           MIN+ N+Q
Sbjct: 402 MINKQNEQ 409
>XP_005251893
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  INQMNQQG 9
          +NQ  QQG
Sbjct: 23 LNQQRQQG 30
>XP_005251892
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  INQMNQQG 9
          +NQ  QQG
Sbjct: 23 LNQQRQQG 30
>XP_006714547
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   MINQMNQQG 9
           M+N  NQ G
Sbjct: 102 MVNATNQMG 110
>NP_954635
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QMNQQG 9
           QMNQ+G
Sbjct: 114 QMNQRG 119
>NP_000679
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QMNQQG 9
           QMNQ+G
Sbjct: 114 QMNQRG 119
>NP_001138295
          Length = 1906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    MINQMNQQ 8
            M+N++NQ+
Sbjct: 1086 MLNRINQE 1093
>NP_005839
          Length = 1863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    MINQMNQQ 8
            M+N++NQ+
Sbjct: 1043 MLNRINQE 1050
>NP_001273052
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  MINQMNQQG 9
          M+N   QQG
Sbjct: 45 MVNTTQQQG 53
>NP_001273054
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  MINQMNQQG 9
          M+N   QQG
Sbjct: 45 MVNTTQQQG 53
>NP_005826
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  MINQMNQQG 9
          M+N   QQG
Sbjct: 45 MVNTTQQQG 53
>NP_060063
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   MINQMNQQ 8
           ++NQMN++
Sbjct: 138 VVNQMNKK 145
>NP_942595
          Length = 1161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   MINQMNQQ 8
           ++NQMN++
Sbjct: 138 VVNQMNKK 145
>XP_005254179
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   MINQMNQQ 8
           M+N++NQ+
Sbjct: 353 MLNRINQE 360
>XP_005254178
          Length = 1863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    MINQMNQQ 8
            M+N++NQ+
Sbjct: 1043 MLNRINQE 1050
>XP_006720435
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    MINQMNQQ 8
            M+N++NQ+
Sbjct: 1087 MLNRINQE 1094
>XP_005254177
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    MINQMNQQ 8
            M+N++NQ+
Sbjct: 1087 MLNRINQE 1094
>XP_006720434
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    MINQMNQQ 8
            M+N++NQ+
Sbjct: 1087 MLNRINQE 1094
>XP_005254176
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    MINQMNQQ 8
            M+N++NQ+
Sbjct: 1087 MLNRINQE 1094
>XP_006715015
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  MINQMNQQG 9
          M+N   QQG
Sbjct: 45 MVNTTQQQG 53
>XP_006715014
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  MINQMNQQG 9
          M+N   QQG
Sbjct: 45 MVNTTQQQG 53
>XP_006715013
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  MINQMNQQG 9
          M+N   QQG
Sbjct: 22 MVNTTQQQG 30
>XP_006715012
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  MINQMNQQG 9
          M+N   QQG
Sbjct: 45 MVNTTQQQG 53
>XP_005248841
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  MINQMNQQG 9
          M+N   QQG
Sbjct: 45 MVNTTQQQG 53
>XP_005263174
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   MINQMNQQ 8
           ++NQMN++
Sbjct: 138 VVNQMNKK 145
>XP_005265002
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QMNQQG 9
           QMNQ+G
Sbjct: 114 QMNQRG 119
>XP_005265001
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QMNQQG 9
           QMNQ+G
Sbjct: 131 QMNQRG 136
>NP_054735
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   MINQMNQQG 9
           +IN +NQ+G
Sbjct: 304 IINLINQKG 312
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.123    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 415,825
Number of extensions: 655
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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