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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              19     869
NP_683692                                                              17    3301
XP_005248208                                                           17    3301
XP_005248207                                                           17    3301
XP_006714021                                                           17    3301
NP_001182068                                                           16    5631
NP_056201                                                              16    5631
NP_002652                                                              16    5631
XP_006721237                                                           16    5631
NP_001128527                                                           15    9605
NP_001244957                                                           15    9605
NP_001055                                                              15    9605
NP_001274693                                                           15    9605
NP_055207                                                              15    9605
NP_596870                                                              15    9605
NP_001274692                                                           15    9605
NP_001035190                                                           15    9605
NP_001008781                                                           15    9605
XP_006713382                                                           15    9605

>NP_115803
          Length = 1156

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   MEKIVIKSK 9
           MEKIVIKS+
Sbjct: 359 MEKIVIKSE 367



>NP_683692
          Length = 3051

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKIVIKSK 9
           EK+V+KSK
Sbjct: 906 EKLVLKSK 913



>XP_005248208
          Length = 3097

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKIVIKSK 9
           EK+V+KSK
Sbjct: 906 EKLVLKSK 913



>XP_005248207
          Length = 3098

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKIVIKSK 9
           EK+V+KSK
Sbjct: 906 EKLVLKSK 913



>XP_006714021
          Length = 3112

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKIVIKSK 9
           EK+V+KSK
Sbjct: 906 EKLVLKSK 913



>NP_001182068
          Length = 768

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MEKIVIKS 8
           +EK+V+KS
Sbjct: 670 LEKVVLKS 677



>NP_056201
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MEKIVIKS 8
           +EK+V+KS
Sbjct: 691 LEKVVLKS 698



>NP_002652
          Length = 1265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKIVIKSK 9
           EKI+IK K
Sbjct: 449 EKIIIKHK 456



>XP_006721237
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   MEKIVIKS 8
           +EK+V+KS
Sbjct: 549 LEKVVLKS 556



>NP_001128527
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KIVIKSK 9
           K+V+KSK
Sbjct: 493 KVVLKSK 499



>NP_001244957
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KIVIKSK 9
           K+V+KSK
Sbjct: 501 KVVLKSK 507



>NP_001055
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KIVIKSK 9
           K+V+KSK
Sbjct: 493 KVVLKSK 499



>NP_001274693
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  EKIVIKSK 9
          +K+V+K+K
Sbjct: 15 DKVVVKTK 22



>NP_055207
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  EKIVIKSK 9
          +K+V+K+K
Sbjct: 42 DKVVVKTK 49



>NP_596870
          Length = 5604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    MEKIVIKS 8
            ME++V+KS
Sbjct: 5491 MEELVLKS 5498



>NP_001274692
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  EKIVIKSK 9
          +K+V+K+K
Sbjct: 42 DKVVVKTK 49



>NP_001035190
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  EKIVIKSK 9
          +K+V+K+K
Sbjct: 42 DKVVVKTK 49



>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EKIVIKSK 9
           EK++IK+K
Sbjct: 694 EKLLIKAK 701



>XP_006713382
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KIVIKSK 9
           K+V+KSK
Sbjct: 493 KVVLKSK 499



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.128    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 396,612
Number of extensions: 673
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)