Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001157994                                                           19     869
XP_006711351                                                           19     869
NP_796377                                                              19     869
NP_789765                                                              17    2528
NP_001123914                                                           17    2528
NP_001405                                                              17    2528
NP_005334                                                              17    2528
NP_004976                                                              17    2528
NP_203524                                                              17    2528
NP_002515                                                              17    2528
NP_001171516                                                           17    2528
NP_001171515                                                           17    2528
NP_079533                                                              17    2528
XP_006725199                                                           17    2528
XP_006719132                                                           17    2528
XP_006718280                                                           17    2528
NP_003827                                                              17    3301
NP_001138528                                                           17    3301
NP_065161                                                              17    3301
XP_005260056                                                           17    3301
XP_005260055                                                           17    3301
XP_005260054                                                           17    3301
NP_000483                                                              17    4312
NP_620598                                                              17    4312
NP_620599                                                              17    4312
NP_004348                                                              17    4312
NP_001034579                                                           17    4312
NP_001152849                                                           17    4312
NP_001152850                                                           17    4312
NP_073601                                                              17    4312
NP_001152851                                                           17    4312
NP_001152852                                                           17    4312
XP_005256170                                                           17    4312
XP_005256156                                                           17    4312
XP_005256164                                                           17    4312
XP_005256158                                                           17    4312
XP_005256160                                                           17    4312
XP_005256157                                                           17    4312
XP_006715905                                                           17    4312
NP_653240                                                              16    5631
NP_001159446                                                           16    5631
NP_001073978                                                           16    5631
NP_775767                                                              16    7355
NP_006047                                                              16    7355
NP_079480                                                              16    7355
NP_001760                                                              16    7355
XP_006724488                                                           16    7355
XP_006724487                                                           16    7355
XP_006724486                                                           16    7355
XP_006724485                                                           16    7355
XP_006724484                                                           16    7355
XP_006724483                                                           16    7355
XP_006724482                                                           16    7355
XP_005252425                                                           16    7355
XP_005252424                                                           16    7355
XP_006712259                                                           16    7355
XP_006712258                                                           16    7355
NP_000080                                                              15    9605
NP_002200                                                              15    9605
NP_705690                                                              15    9605
NP_001107852                                                           15    9605
NP_036344                                                              15    9605
NP_001158297                                                           15    9605
NP_001139581                                                           15    9605
NP_001139580                                                           15    9605
NP_001158296                                                           15    9605
NP_001002026                                                           15    9605
NP_612437                                                              15    9605
NP_919417                                                              15    9605
NP_056535                                                              15    9605
XP_006721107                                                           15    9605
XP_005255370                                                           15    9605
XP_005270460                                                           15    9605
NP_001001918                                                           15    9605
NP_057453                                                              15    9605
>NP_001157994
          Length = 199

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LVVVGAVGV 9
          L++VGA+GV
Sbjct: 11 LIIVGAIGV 19
>XP_006711351
          Length = 189

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LVVVGAVGV 9
          L++VGA+GV
Sbjct: 11 LIIVGAIGV 19
>NP_796377
          Length = 199

 Score = 18.9 bits (37), Expect =   869
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LVVVGAVGV 9
          L++VGA+GV
Sbjct: 11 LIIVGAIGV 19
>NP_789765
          Length = 170

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>NP_001123914
          Length = 189

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>NP_001405
          Length = 305

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LV+VGA GV
Sbjct: 192 LVIVGAEGV 200
>NP_005334
          Length = 189

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>NP_004976
          Length = 188

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>NP_203524
          Length = 189

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>NP_002515
          Length = 189

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>NP_001171516
          Length = 634

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           L+VVG VGV
Sbjct: 528 LLVVGGVGV 536
>NP_001171515
          Length = 668

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           L+VVG VGV
Sbjct: 562 LLVVGGVGV 570
>NP_079533
          Length = 710

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           L+VVG VGV
Sbjct: 604 LLVVGGVGV 612
>XP_006725199
          Length = 170

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>XP_006719132
          Length = 189

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>XP_006718280
          Length = 170

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVVGAVGV 9
          LVVVGA GV
Sbjct: 6  LVVVGAGGV 14
>NP_003827
          Length = 383

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVV+G VG+
Sbjct: 316 LVVLGTVGI 324
>NP_001138528
          Length = 704

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LVVVGAVGV 9
           L++VG+VG+
Sbjct: 605 LLIVGSVGI 613
>NP_065161
          Length = 706

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LVVVGAVGV 9
           L++VG+VG+
Sbjct: 607 LLIVGSVGI 615
>XP_005260056
          Length = 709

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LVVVGAVGV 9
           L++VG+VG+
Sbjct: 605 LLIVGSVGI 613
>XP_005260055
          Length = 711

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LVVVGAVGV 9
           L++VG+VG+
Sbjct: 607 LLIVGSVGI 615
>XP_005260054
          Length = 711

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LVVVGAVGV 9
           L++VG+VG+
Sbjct: 607 LLIVGSVGI 615
>NP_000483
          Length = 1480

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LVVVGAVGV 9
            L+V+GA+ V
Sbjct: 999  LIVIGAIAV 1007
>NP_620598
          Length = 253

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           L V+GAVG+
Sbjct: 220 LRVIGAVGI 228
>NP_620599
          Length = 253

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           L V+GAVG+
Sbjct: 220 LRVIGAVGI 228
>NP_004348
          Length = 253

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           L V+GAVG+
Sbjct: 220 LRVIGAVGI 228
>NP_001034579
          Length = 253

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           L V+GAVG+
Sbjct: 220 LRVIGAVGI 228
>NP_001152849
          Length = 383

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 136 LVVVGSVAV 144
>NP_001152850
          Length = 383

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 136 LVVVGSVAV 144
>NP_073601
          Length = 382

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 135 LVVVGSVAV 143
>NP_001152851
          Length = 382

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 135 LVVVGSVAV 143
>NP_001152852
          Length = 363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 116 LVVVGSVAV 124
>XP_005256170
          Length = 363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 116 LVVVGSVAV 124
>XP_005256156
          Length = 363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 116 LVVVGSVAV 124
>XP_005256164
          Length = 231

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 136 LVVVGSVAV 144
>XP_005256158
          Length = 363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 116 LVVVGSVAV 124
>XP_005256160
          Length = 363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 116 LVVVGSVAV 124
>XP_005256157
          Length = 363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           LVVVG+V V
Sbjct: 116 LVVVGSVAV 124
>XP_006715905
          Length = 1588

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    LVVVGAVGV 9
            L+V+GA+ V
Sbjct: 1107 LIVIGAIAV 1115
>NP_653240
          Length = 676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           V+VG +GV
Sbjct: 261 VIVGCIGV 268
>NP_001159446
          Length = 736

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           V+VG +GV
Sbjct: 261 VIVGCIGV 268
>NP_001073978
          Length = 253

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LVVVGAVGV 9
           L+++GAVG+
Sbjct: 220 LLLMGAVGI 228
>NP_775767
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           +V+VG VGV
Sbjct: 371 VVLVGPVGV 379
>NP_006047
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LVVVGAVG 8
          + VVGAVG
Sbjct: 70 IFVVGAVG 77
>NP_079480
          Length = 376

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           VVVG VG+
Sbjct: 291 VVVGVVGM 298
>NP_001760
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VVGAVGV 9
           ++GAVG+
Sbjct: 195 IIGAVGI 201
>XP_006724488
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           VVVG VG+
Sbjct: 291 VVVGVVGM 298
>XP_006724487
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           VVVG VG+
Sbjct: 291 VVVGVVGM 298
>XP_006724486
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           VVVG VG+
Sbjct: 291 VVVGVVGM 298
>XP_006724485
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           VVVG VG+
Sbjct: 291 VVVGVVGM 298
>XP_006724484
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           VVVG VG+
Sbjct: 307 VVVGVVGM 314
>XP_006724483
          Length = 392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           VVVG VG+
Sbjct: 307 VVVGVVGM 314
>XP_006724482
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VVVGAVGV 9
           VVVG VG+
Sbjct: 307 VVVGVVGM 314
>XP_005252425
          Length = 499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           +V+VG VGV
Sbjct: 371 VVLVGPVGV 379
>XP_005252424
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           +V+VG VGV
Sbjct: 371 VVLVGPVGV 379
>XP_006712259
          Length = 333

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LVVVGAVG 8
          + VVGAVG
Sbjct: 70 IFVVGAVG 77
>XP_006712258
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LVVVGAVG 8
          + VVGAVG
Sbjct: 70 IFVVGAVG 77
>NP_000080
          Length = 1366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VVGAVG 8
           VVGAVG
Sbjct: 626 VVGAVG 631
>NP_002200
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VVGAVG 8
           VVGAVG
Sbjct: 364 VVGAVG 369
>NP_705690
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGAVGV 9
           VGAVGV
Sbjct: 480 VGAVGV 485
>NP_001107852
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VVGAVG 8
           VVGAVG
Sbjct: 281 VVGAVG 286
>NP_036344
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VVGAVG 8
           VVGAVG
Sbjct: 169 VVGAVG 174
>NP_001158297
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  VVGAVG 8
          VVGAVG
Sbjct: 23 VVGAVG 28
>NP_001139581
          Length = 301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VVGAVG 8
           VVGAVG
Sbjct: 169 VVGAVG 174
>NP_001139580
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VVGAVG 8
           VVGAVG
Sbjct: 169 VVGAVG 174
>NP_001158296
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  VVGAVG 8
          VVGAVG
Sbjct: 23 VVGAVG 28
>NP_001002026
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  VVVGAVGV 9
          +V+GA+G+
Sbjct: 87 IVLGAIGL 94
>NP_612437
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  VVGAVG 8
          VVGAVG
Sbjct: 23 VVGAVG 28
>NP_919417
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGAVGV 9
           VGAVGV
Sbjct: 457 VGAVGV 462
>NP_056535
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LVVVGAV 7
           LVV+GA+
Sbjct: 505 LVVIGAI 511
>XP_006721107
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VVGAVG 8
           VVGAVG
Sbjct: 281 VVGAVG 286
>XP_005255370
          Length = 1169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VVGAVG 8
           VVGAVG
Sbjct: 364 VVGAVG 369
>XP_005270460
          Length = 92

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  VVGAVG 8
          VVGAVG
Sbjct: 23 VVGAVG 28
>NP_001001918
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LVVVGAVGV 9
           ++VV A+GV
Sbjct: 196 MIVVSALGV 204
>NP_057453
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  VVVGAVGV 9
          +V+GA+G+
Sbjct: 87 IVLGAIGL 94
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.152    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 361,416
Number of extensions: 815
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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