Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
XP_006726410                                                           18    1482
XP_006711719                                                           18    1482
XP_006711718                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
XP_006711164                                                           18    1482
XP_005276153                                                           18    1482
XP_003846805                                                           18    1482
NP_001177111                                                           16    5631
NP_001108410                                                           16    5631
NP_078886                                                              16    5631
XP_005247818                                                           16    5631
XP_005270591                                                           16    5631
XP_006710452                                                           16    5631
XP_006710451                                                           16    5631
NP_671494                                                              16    7355
NP_937770                                                              16    7355
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 1941 LVAEVRALR 1949
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2047 LVAEVRALR 2055
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2047 LVAEVRALR 2055
>XP_006726410
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 1788 LVAEVRALR 1796
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2003 LVAEVRALR 2011
>XP_006711718
          Length = 1436

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 1054 LVAEVRALR 1062
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2003 LVAEVRALR 2011
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2112 LVAEVRALR 2120
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2046 LVAEVRALR 2054
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2047 LVAEVRALR 2055
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2050 LVAEVRALR 2058
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2100 LVAEVRALR 2108
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2112 LVAEVRALR 2120
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2113 LVAEVRALR 2121
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2210 LVAEVRALR 2218
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2210 LVAEVRALR 2218
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2210 LVAEVRALR 2218
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2210 LVAEVRALR 2218
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2210 LVAEVRALR 2218
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2209 LVAEVRALR 2217
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 2210 LVAEVRALR 2218
>XP_006711164
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVVEVRALR 9
            LV EVRALR
Sbjct: 1788 LVAEVRALR 1796
>XP_005276153
          Length = 267

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVEVRALR 9
          LV EVRALR
Sbjct: 43 LVAEVRALR 51
>XP_003846805
          Length = 306

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVVEVRALR 9
          LV EVRALR
Sbjct: 43 LVAEVRALR 51
>NP_001177111
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LVVEVRALR 9
           L  E+RALR
Sbjct: 233 LAAEIRALR 241
>NP_001108410
          Length = 622

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LVVEVRALR 9
           L  E+RALR
Sbjct: 242 LAAEIRALR 250
>NP_078886
          Length = 488

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VVEVRALR 9
           VVE++ALR
Sbjct: 341 VVEIQALR 348
>XP_005247818
          Length = 460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VVEVRALR 9
           VVE++ALR
Sbjct: 313 VVEIQALR 320
>XP_005270591
          Length = 443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LVVEVRALR 9
          L  E+RALR
Sbjct: 63 LAAEIRALR 71
>XP_006710452
          Length = 660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LVVEVRALR 9
           L  E+RALR
Sbjct: 233 LAAEIRALR 241
>XP_006710451
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LVVEVRALR 9
           L  E+RALR
Sbjct: 242 LAAEIRALR 250
>NP_671494
          Length = 1249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    LVVEVRAL 8
            LVVEVR L
Sbjct: 1230 LVVEVRRL 1237
>NP_937770
          Length = 472

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVVEVRALR 9
           +V EVRA+R
Sbjct: 401 IVEEVRAIR 409
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.150    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 240,846
Number of extensions: 250
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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