Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000360                                                              18    1935
XP_005268094                                                           18    1935
NP_660333                                                              17    3301
XP_005248194                                                           17    3301
NP_065075                                                              17    4312
XP_005246746                                                           17    4312
NP_001120729                                                           17    4312
NP_001176                                                              16    5631
NP_795364                                                              16    5631
NP_958434                                                              16    7355
NP_004359                                                              16    7355
NP_078875                                                              16    7355
NP_001243770                                                           16    7355
NP_009192                                                              16    7355
NP_001005498                                                           16    7355
XP_005257727                                                           16    7355
XP_006722145                                                           16    7355
XP_006722144                                                           16    7355
XP_006722143                                                           16    7355
XP_006722142                                                           16    7355
XP_005257726                                                           16    7355
XP_006721719                                                           16    7355
XP_005257049                                                           16    7355
XP_005257048                                                           16    7355
XP_005257047                                                           16    7355
NP_001702                                                              15    9605
NP_852111                                                              15    9605
NP_000136                                                              15    9605
NP_001129686                                                           15    9605
NP_872425                                                              15    9605
NP_757385                                                              15    9605
NP_001185863                                                           15    9605
NP_258261                                                              15    9605
NP_115807                                                              15    9605
NP_001258126                                                           15    9605
NP_065139                                                              15    9605
XP_005256033                                                           15    9605
XP_005256032                                                           15    9605
XP_005255993                                                           15    9605
XP_005255991                                                           15    9605
XP_005255990                                                           15    9605
XP_005255989                                                           15    9605
XP_005255965                                                           15    9605
XP_006721242                                                           15    9605
XP_005255963                                                           15    9605
XP_006718776                                                           15    9605
XP_006718775                                                           15    9605
XP_006715707                                                           15    9605
XP_005249672                                                           15    9605
XP_006715706                                                           15    9605
XP_006715705                                                           15    9605
XP_005249670                                                           15    9605
XP_006715303                                                           15    9605
NP_001011880                                                           15    9605
NP_543011                                                              15    9605
NP_775890                                                              15    9605
NP_612454                                                              15    9605
>NP_000360
          Length = 764

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VSLLALLG 9
           VSLLALLG
Sbjct: 424 VSLLALLG 431
>XP_005268094
          Length = 764

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VSLLALLG 9
           VSLLALLG
Sbjct: 424 VSLLALLG 431
>NP_660333
          Length = 1321

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1  LVSLLALLG 9
          L++LLALLG
Sbjct: 21 LLALLALLG 29
>XP_005248194
          Length = 833

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1  LVSLLALLG 9
          L++LLALLG
Sbjct: 21 LLALLALLG 29
>NP_065075
          Length = 831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LVSLLALLG 9
           ++SLL+LLG
Sbjct: 416 VISLLSLLG 424
>XP_005246746
          Length = 898

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LVSLLALLG 9
           ++SLL+LLG
Sbjct: 483 VISLLSLLG 491
>NP_001120729
          Length = 831

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LVSLLALLG 9
           ++SLL+LLG
Sbjct: 416 VISLLSLLG 424
>NP_001176
          Length = 298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LVSLLALLG 9
          L+SLL LLG
Sbjct: 8  LLSLLLLLG 16
>NP_795364
          Length = 307

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LVSLLALLG 9
          L SLL+LLG
Sbjct: 12 LFSLLSLLG 20
>NP_958434
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VSLLALLG 9
           VSLLAL G
Sbjct: 122 VSLLALAG 129
>NP_004359
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   VSLLALLG 9
           VSLLAL G
Sbjct: 122 VSLLALAG 129
>NP_078875
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LVSLLALLG 9
           LVSLLA  G
Sbjct: 806 LVSLLAFAG 814
>NP_001243770
          Length = 186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  LVSLLALL 8
          L+SLLALL
Sbjct: 69 LLSLLALL 76
>NP_009192
          Length = 299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LVSLLALL 8
           L+SLLALL
Sbjct: 182 LLSLLALL 189
>NP_001005498
          Length = 827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LVSLLALLG 9
           LVSLLA  G
Sbjct: 777 LVSLLAFAG 785
>XP_005257727
          Length = 827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LVSLLALLG 9
           LVSLLA  G
Sbjct: 777 LVSLLAFAG 785
>XP_006722145
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LVSLLALLG 9
           LVSLLA  G
Sbjct: 801 LVSLLAFAG 809
>XP_006722144
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LVSLLALLG 9
           LVSLLA  G
Sbjct: 801 LVSLLAFAG 809
>XP_006722143
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LVSLLALLG 9
           LVSLLA  G
Sbjct: 801 LVSLLAFAG 809
>XP_006722142
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LVSLLALLG 9
           LVSLLA  G
Sbjct: 801 LVSLLAFAG 809
>XP_005257726
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LVSLLALLG 9
           LVSLLA  G
Sbjct: 806 LVSLLAFAG 814
>XP_006721719
          Length = 169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  LVSLLALL 8
          L+SLLALL
Sbjct: 52 LLSLLALL 59
>XP_005257049
          Length = 169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  LVSLLALL 8
          L+SLLALL
Sbjct: 52 LLSLLALL 59
>XP_005257048
          Length = 223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LVSLLALL 8
           L+SLLALL
Sbjct: 182 LLSLLALL 189
>XP_005257047
          Length = 263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LVSLLALL 8
           L+SLLALL
Sbjct: 182 LLSLLALL 189
>NP_001702
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  LVSLLAL 7
          LVSLLAL
Sbjct: 7  LVSLLAL 13
>NP_852111
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  LVSLLALL 8
          LVSLLA L
Sbjct: 5  LVSLLAFL 12
>NP_000136
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  LVSLLALL 8
          LVSLLA L
Sbjct: 5  LVSLLAFL 12
>NP_001129686
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>NP_872425
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>NP_757385
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVSLLALLG 9
           +VSL+ LLG
Sbjct: 141 IVSLMFLLG 149
>NP_001185863
          Length = 1492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVSLLALLG 9
            L+ LLA+LG
Sbjct: 1053 LLGLLAVLG 1061
>NP_258261
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVSLLALLG 9
            L+ LLA+LG
Sbjct: 1025 LLGLLAVLG 1033
>NP_115807
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVSLLALLG 9
           +VSL+ LLG
Sbjct: 141 IVSLMFLLG 149
>NP_001258126
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>NP_065139
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  VSLLALLG 9
          V LLALLG
Sbjct: 4  VLLLALLG 11
>XP_005256033
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_005256032
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_005255993
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_005255991
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_005255990
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_005255989
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_005255965
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_006721242
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_005255963
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>XP_006718776
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVSLLALLG 9
           +VSL+ LLG
Sbjct: 141 IVSLMFLLG 149
>XP_006718775
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVSLLALLG 9
           +VSL+ LLG
Sbjct: 141 IVSLMFLLG 149
>XP_006715707
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VSLLALLG 9
          +SLL+LLG
Sbjct: 26 LSLLSLLG 33
>XP_005249672
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VSLLALLG 9
          +SLL+LLG
Sbjct: 26 LSLLSLLG 33
>XP_006715706
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VSLLALLG 9
          +SLL+LLG
Sbjct: 26 LSLLSLLG 33
>XP_006715705
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VSLLALLG 9
          +SLL+LLG
Sbjct: 44 LSLLSLLG 51
>XP_005249670
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VSLLALLG 9
           +SLL+LLG
Sbjct: 238 LSLLSLLG 245
>XP_006715303
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVSLLALLG 9
            L+ LLA+LG
Sbjct: 1053 LLGLLAVLG 1061
>NP_001011880
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>NP_543011
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1 LVSLLALLG 9
         +  LLALLG
Sbjct: 1 MAGLLALLG 9
>NP_775890
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVSLLALLG 9
          L  LLALLG
Sbjct: 14 LAVLLALLG 22
>NP_612454
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VSLLALLG 9
          +SLL+LLG
Sbjct: 26 LSLLSLLG 33
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.154    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 301,692
Number of extensions: 446
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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