Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              20     390
NP_001120972                                                           20     390
XP_006716052                                                           20     390
XP_006716051                                                           20     390
NP_001074025                                                           18    1135
XP_005256532                                                           18    1135
NP_659491                                                              18    1135
NP_001127945                                                           18    1935
NP_001265113                                                           18    1935
NP_055430                                                              18    1935
XP_005255922                                                           18    1935
XP_006721236                                                           18    1935
XP_006721235                                                           18    1935
XP_005255921                                                           18    1935
XP_005255920                                                           18    1935
XP_005255919                                                           18    1935
XP_005255918                                                           18    1935
XP_005255917                                                           18    1935
XP_005255916                                                           18    1935
NP_005064                                                              17    2528
NP_079092                                                              17    2528
NP_001241657                                                           17    3301
NP_001241658                                                           17    3301
NP_009008                                                              17    3301
NP_001241656                                                           17    3301
NP_001241655                                                           17    3301
NP_001121598                                                           17    3301
XP_005267350                                                           17    3301
XP_005272048                                                           17    3301
XP_006714680                                                           17    3301
NP_060626                                                              17    4312
NP_056193                                                              17    4312
NP_434701                                                              17    4312
NP_434700                                                              17    4312
NP_065924                                                              17    4312
XP_005265408                                                           17    4312
NP_006608                                                              16    5631
NP_071894                                                              16    5631
XP_006712752                                                           16    5631
NP_002996                                                              16    7355
NP_055417                                                              16    7355
NP_006368                                                              16    7355
NP_001073890                                                           16    7355
XP_006722755                                                           16    7355
XP_006716779                                                           16    7355
XP_005245497                                                           16    7355
XP_005245496                                                           16    7355
XP_005245495                                                           16    7355
XP_005245493                                                           16    7355
XP_005245492                                                           16    7355
NP_003289                                                              15    9605
NP_065974                                                              15    9605
NP_001272478                                                           15    9605
NP_071741                                                              15    9605
NP_001271286                                                           15    9605
NP_851826                                                              15    9605
NP_001185947                                                           15    9605
NP_001185946                                                           15    9605
NP_443194                                                              15    9605
NP_079303                                                              15    9605
NP_060161                                                              15    9605
XP_005259334                                                           15    9605
XP_005259333                                                           15    9605
XP_006714035                                                           15    9605
XP_006714034                                                           15    9605
XP_005247312                                                           15    9605
XP_006713383                                                           15    9605
XP_005265485                                                           15    9605
XP_006712721                                                           15    9605
XP_006712720                                                           15    9605
XP_006712719                                                           15    9605
XP_005246770                                                           15    9605
XP_005246768                                                           15    9605
XP_005246769                                                           15    9605
>NP_000236
          Length = 1390

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVQRSNEEC 9
          LVQRSN EC
Sbjct: 18 LVQRSNGEC 26
>NP_001120972
          Length = 1408

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVQRSNEEC 9
          LVQRSN EC
Sbjct: 18 LVQRSNGEC 26
>XP_006716052
          Length = 1409

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVQRSNEEC 9
          LVQRSN EC
Sbjct: 37 LVQRSNGEC 45
>XP_006716051
          Length = 1427

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVQRSNEEC 9
          LVQRSN EC
Sbjct: 37 LVQRSNGEC 45
>NP_001074025
          Length = 552

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VQRSNEEC 9
           V+R+NEEC
Sbjct: 401 VKRNNEEC 408
>XP_005256532
          Length = 531

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VQRSNEEC 9
           V+R+NEEC
Sbjct: 380 VKRNNEEC 387
>NP_659491
          Length = 620

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VQRSNEEC 9
           V+R+NEEC
Sbjct: 469 VKRNNEEC 476
>NP_001127945
          Length = 1113

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QR+NEE
Sbjct: 383 LIQRTNEE 390
>NP_001265113
          Length = 1144

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QR+NEE
Sbjct: 414 LIQRTNEE 421
>NP_055430
          Length = 1217

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QR+NEE
Sbjct: 487 LIQRTNEE 494
>XP_005255922
          Length = 1154

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QR+NEE
Sbjct: 424 LIQRTNEE 431
>XP_006721236
          Length = 1214

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QR+NEE
Sbjct: 484 LIQRTNEE 491
>XP_006721235
          Length = 1214

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QR+NEE
Sbjct: 484 LIQRTNEE 491
>XP_005255921
          Length = 1227

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QR+NEE
Sbjct: 497 LIQRTNEE 504
>XP_005255920
          Length = 1229

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QR+NEE
Sbjct: 499 LIQRTNEE 506
>XP_005255919
          Length = 1860

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LVQRSNEE 8
            L+QR+NEE
Sbjct: 1292 LIQRTNEE 1299
>XP_005255918
          Length = 1949

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LVQRSNEE 8
            L+QR+NEE
Sbjct: 1219 LIQRTNEE 1226
>XP_005255917
          Length = 1984

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LVQRSNEE 8
            L+QR+NEE
Sbjct: 1292 LIQRTNEE 1299
>XP_005255916
          Length = 2022

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    LVQRSNEE 8
            L+QR+NEE
Sbjct: 1292 LIQRTNEE 1299
>NP_005064
          Length = 708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LVQRSNEEC 9
           +VQR N+ C
Sbjct: 557 IVQRKNDSC 565
>NP_079092
          Length = 569

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VQRSNEEC 9
           ++RSNE+C
Sbjct: 320 LRRSNEDC 327
>NP_001241657
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VQRSNEEC 9
          + RSNE+C
Sbjct: 40 LSRSNEQC 47
>NP_001241658
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VQRSNEEC 9
          + RSNE+C
Sbjct: 40 LSRSNEQC 47
>NP_009008
          Length = 159

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VQRSNEEC 9
          + RSNE+C
Sbjct: 40 LSRSNEQC 47
>NP_001241656
          Length = 149

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VQRSNEEC 9
          + RSNE+C
Sbjct: 40 LSRSNEQC 47
>NP_001241655
          Length = 135

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VQRSNEEC 9
          + RSNE+C
Sbjct: 40 LSRSNEQC 47
>NP_001121598
          Length = 144

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VQRSNEEC 9
          + RSNE+C
Sbjct: 40 LSRSNEQC 47
>XP_005267350
          Length = 159

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  VQRSNEEC 9
          + RSNE+C
Sbjct: 40 LSRSNEQC 47
>XP_005272048
          Length = 851

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VQRSNEEC 9
           V+RS++EC
Sbjct: 705 VERSSDEC 712
>XP_006714680
          Length = 1002

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VQRSNEEC 9
           V+RS++EC
Sbjct: 856 VERSSDEC 863
>NP_060626
          Length = 4363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VQRSNEEC 9
            V+RS +EC
Sbjct: 1275 VERSKQEC 1282
>NP_056193
          Length = 4388

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VQRSNEEC 9
            V+RS +EC
Sbjct: 1275 VERSKQEC 1282
>NP_434701
          Length = 492

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VQRSNEEC 9
           VQR  EEC
Sbjct: 161 VQRLKEEC 168
>NP_434700
          Length = 536

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VQRSNEEC 9
           VQR  EEC
Sbjct: 161 VQRLKEEC 168
>NP_065924
          Length = 716

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LVQRSNEEC 9
           L+Q S+E+C
Sbjct: 414 LIQDSSEQC 422
>XP_005265408
          Length = 716

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LVQRSNEEC 9
           L+Q S+E+C
Sbjct: 414 LIQDSSEQC 422
>NP_006608
          Length = 1621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VQRSNEEC 9
           ++R N+EC
Sbjct: 568 LERENQEC 575
>NP_071894
          Length = 212

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QRS+EE
Sbjct: 180 LLQRSDEE 187
>XP_006712752
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVQRSNEE 8
           L+QRS+EE
Sbjct: 158 LLQRSDEE 165
>NP_002996
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QRSNEEC 9
           +R+NE+C
Sbjct: 125 KRNNEDC 131
>NP_055417
          Length = 1358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   LVQRSNEEC 9
           L+Q+  E+C
Sbjct: 947 LIQQKREQC 955
>NP_006368
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LVQRSNEE 8
            L QRSN+E
Sbjct: 1565 LSQRSNDE 1572
>NP_001073890
          Length = 1703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LVQRSNEE 8
            L QRSN+E
Sbjct: 1672 LSQRSNDE 1679
>XP_006722755
          Length = 1722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LVQRSNEE 8
            L QRSN+E
Sbjct: 1691 LSQRSNDE 1698
>XP_006716779
          Length = 2399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LVQRSNEE 8
            L QRSN+E
Sbjct: 2373 LSQRSNDE 2380
>XP_005245497
          Length = 768

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QRSNEEC 9
           +R+NE+C
Sbjct: 125 KRNNEDC 131
>XP_005245496
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QRSNEEC 9
           +R+NE+C
Sbjct: 125 KRNNEDC 131
>XP_005245495
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QRSNEEC 9
           +R+NE+C
Sbjct: 125 KRNNEDC 131
>XP_005245493
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QRSNEEC 9
           +R+NE+C
Sbjct: 125 KRNNEDC 131
>XP_005245492
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   QRSNEEC 9
           +R+NE+C
Sbjct: 125 KRNNEDC 131
>NP_003289
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   RSNEEC 9
           RSN++C
Sbjct: 173 RSNQDC 178
>NP_065974
          Length = 2354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LVQRSNEEC 9
           L  +SNE C
Sbjct: 817 LESKSNESC 825
>NP_001272478
          Length = 2352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LVQRSNEEC 9
           L  +SNE C
Sbjct: 815 LESKSNESC 823
>NP_071741
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   RSNEEC 9
           R+N+EC
Sbjct: 764 RTNQEC 769
>NP_001271286
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LVQRSNEE 8
          ++QRS+EE
Sbjct: 70 ILQRSSEE 77
>NP_851826
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   QRSNEEC 9
           QRS E C
Sbjct: 221 QRSEERC 227
>NP_001185947
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LVQRSNEE 8
          ++QRS+EE
Sbjct: 36 ILQRSSEE 43
>NP_001185946
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LVQRSNEE 8
          ++QRS+EE
Sbjct: 85 ILQRSSEE 92
>NP_443194
          Length = 263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   QRSNEEC 9
           QRS E C
Sbjct: 253 QRSEERC 259
>NP_079303
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LVQRSNEEC 9
           L QRS+E C
Sbjct: 205 LSQRSSEFC 213
>NP_060161
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LVQRSNEE 8
          ++QRS+EE
Sbjct: 80 ILQRSSEE 87
>XP_005259334
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LVQRSNEEC 9
           L QRS+E C
Sbjct: 115 LSQRSSEFC 123
>XP_005259333
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LVQRSNEEC 9
           L QRS+E C
Sbjct: 205 LSQRSSEFC 213
>XP_006714035
          Length = 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   RSNEEC 9
           R+N+EC
Sbjct: 764 RTNQEC 769
>XP_006714034
          Length = 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   RSNEEC 9
           R+N+EC
Sbjct: 764 RTNQEC 769
>XP_005247312
          Length = 1231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4  RSNEEC 9
          R+NE+C
Sbjct: 30 RTNEDC 35
>XP_006713383
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   RSNEEC 9
           RSN++C
Sbjct: 173 RSNQDC 178
>XP_005265485
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   RSNEEC 9
           RSN++C
Sbjct: 154 RSNQDC 159
>XP_006712721
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LVQRSNEEC 9
           L  +SNE C
Sbjct: 817 LESKSNESC 825
>XP_006712720
          Length = 1991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LVQRSNEEC 9
           L  +SNE C
Sbjct: 817 LESKSNESC 825
>XP_006712719
          Length = 2354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LVQRSNEEC 9
           L  +SNE C
Sbjct: 817 LESKSNESC 825
>XP_005246770
          Length = 2354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LVQRSNEEC 9
           L  +SNE C
Sbjct: 817 LESKSNESC 825
>XP_005246768
          Length = 2354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LVQRSNEEC 9
           L  +SNE C
Sbjct: 817 LESKSNESC 825
>XP_005246769
          Length = 2354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LVQRSNEEC 9
           L  +SNE C
Sbjct: 817 LESKSNESC 825
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.124    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 593,008
Number of extensions: 1143
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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