Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           19     665
NP_004561                                                              19     665
NP_001275703                                                           19     665
XP_005253450                                                           19     665
XP_006719151                                                           19     665
NP_056380                                                              18    1935
NP_055437                                                              17    3301
NP_001123614                                                           17    3301
NP_055059                                                              16    5631
NP_057728                                                              16    5631
NP_631894                                                              16    5631
NP_542453                                                              16    5631
NP_067610                                                              16    5631
NP_055058                                                              16    5631
XP_005272069                                                           16    5631
XP_005272068                                                           16    5631
XP_005272067                                                           16    5631
NP_001244118                                                           16    7355
NP_001018011                                                           16    7355
NP_064703                                                              16    7355
NP_061955                                                              16    7355
NP_005997                                                              16    7355
XP_006725230                                                           16    7355
XP_006720283                                                           16    7355
XP_006719813                                                           16    7355
XP_005271715                                                           16    7355
XP_006718962                                                           16    7355
XP_006713774                                                           16    7355
XP_005247708                                                           16    7355
XP_005247704                                                           16    7355
XP_006713773                                                           16    7355
NP_065869                                                              16    7355
NP_005017                                                              15    9605
NP_001186308                                                           15    9605
NP_689967                                                              15    9605
NP_001186307                                                           15    9605
NP_001161707                                                           15    9605
NP_004184                                                              15    9605
XP_006718114                                                           15    9605
XP_005270318                                                           15    9605
XP_006718113                                                           15    9605
XP_006718112                                                           15    9605
XP_006718111                                                           15    9605
XP_006718110                                                           15    9605
XP_006710753                                                           15    9605
XP_005263530                                                           15    9605
XP_006710752                                                           15    9605
XP_006710751                                                           15    9605
XP_006710750                                                           15    9605
XP_006710749                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLLFHRS 9
           LVQLL HRS
Sbjct: 815 LVQLLLHRS 823
>NP_004561
          Length = 1445

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLLFHRS 9
           LVQLL HRS
Sbjct: 774 LVQLLLHRS 782
>NP_001275703
          Length = 1264

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLLFHRS 9
           LVQLL HRS
Sbjct: 593 LVQLLLHRS 601
>XP_005253450
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLLFHRS 9
           LVQLL HRS
Sbjct: 815 LVQLLLHRS 823
>XP_006719151
          Length = 1486

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLLFHRS 9
           LVQLL HRS
Sbjct: 815 LVQLLLHRS 823
>NP_056380
          Length = 1812

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    LVQLLFHRS 9
            L+QLLF+RS
Sbjct: 1119 LLQLLFNRS 1127
>NP_055437
          Length = 786

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LVQLLFHRS 9
           LVQL++H++
Sbjct: 681 LVQLIYHQN 689
>NP_001123614
          Length = 786

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LVQLLFHRS 9
           LVQL++H++
Sbjct: 681 LVQLIYHQN 689
>NP_055059
          Length = 1211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LVQLLFHR 8
           LVQ  FHR
Sbjct: 438 LVQAAFHR 445
>NP_057728
          Length = 281

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VQLLFHR 8
           VQLL HR
Sbjct: 161 VQLLMHR 167
>NP_631894
          Length = 1226

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LVQLLFHR 8
           LVQ  FHR
Sbjct: 431 LVQAAFHR 438
>NP_542453
          Length = 1223

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LVQLLFHR 8
           LVQ  FHR
Sbjct: 428 LVQAAFHR 435
>NP_067610
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LVQLLFHR 8
           LVQ  FHR
Sbjct: 438 LVQAAFHR 445
>NP_055058
          Length = 1205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LVQLLFHR 8
           LVQ  FHR
Sbjct: 428 LVQAAFHR 435
>XP_005272069
          Length = 234

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VQLLFHR 8
           VQLL HR
Sbjct: 114 VQLLMHR 120
>XP_005272068
          Length = 255

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VQLLFHR 8
           VQLL HR
Sbjct: 135 VQLLMHR 141
>XP_005272067
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VQLLFHR 8
           VQLL HR
Sbjct: 184 VQLLMHR 190
>NP_001244118
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LVQLLFHR 8
          ++QLL HR
Sbjct: 65 MLQLLLHR 72
>NP_001018011
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LVQLLFHRS 9
          + ++LFHR+
Sbjct: 58 MFEILFHRN 66
>NP_064703
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QLLFHR 8
           Q+LFHR
Sbjct: 108 QVLFHR 113
>NP_061955
          Length = 547

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LVQLLFHR 8
          ++QLL HR
Sbjct: 65 MLQLLLHR 72
>NP_005997
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LVQLLFHRS 9
          + ++LFHR+
Sbjct: 58 MFEILFHRN 66
>XP_006725230
          Length = 2636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   VQLLFH 7
           VQ+LFH
Sbjct: 275 VQMLFH 280
>XP_006720283
          Length = 2636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   VQLLFH 7
           VQ+LFH
Sbjct: 275 VQMLFH 280
>XP_006719813
          Length = 190

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   LLFHRS 9
           L+FHRS
Sbjct: 178 LMFHRS 183
>XP_005271715
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LVQLLFHRS 9
          + ++LFHR+
Sbjct: 58 MFEILFHRN 66
>XP_006718962
          Length = 523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  LVQLLFHRS 9
          + ++LFHR+
Sbjct: 58 MFEILFHRN 66
>XP_006713774
          Length = 232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QLLFHR 8
           Q+LFHR
Sbjct: 108 QVLFHR 113
>XP_005247708
          Length = 232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QLLFHR 8
           Q+LFHR
Sbjct: 108 QVLFHR 113
>XP_005247704
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QLLFHR 8
           Q+LFHR
Sbjct: 108 QVLFHR 113
>XP_006713773
          Length = 493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QLLFHR 8
           Q+LFHR
Sbjct: 108 QVLFHR 113
>NP_065869
          Length = 2458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   VQLLFH 7
           VQ+LFH
Sbjct: 97  VQMLFH 102
>NP_005017
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QLLFHRS 9
          QLL+HR+
Sbjct: 47 QLLWHRA 53
>NP_001186308
          Length = 1855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>NP_689967
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LVQLLFHR 8
           LVQL  HR
Sbjct: 526 LVQLSLHR 533
>NP_001186307
          Length = 1856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>NP_001161707
          Length = 2139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LVQLLFH 7
           +VQL FH
Sbjct: 669 MVQLAFH 675
>NP_004184
          Length = 1859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>XP_006718114
          Length = 1850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>XP_005270318
          Length = 1860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>XP_006718113
          Length = 1881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>XP_006718112
          Length = 1889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>XP_006718111
          Length = 1892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>XP_006718110
          Length = 1893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVQLLFHR 8
           +VQLLF R
Sbjct: 188 MVQLLFTR 195
>XP_006710753
          Length = 1015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QLLFHRS 9
          QLL+HR+
Sbjct: 47 QLLWHRA 53
>XP_005263530
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QLLFHRS 9
          QLL+HR+
Sbjct: 47 QLLWHRA 53
>XP_006710752
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QLLFHRS 9
          QLL+HR+
Sbjct: 47 QLLWHRA 53
>XP_006710751
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QLLFHRS 9
          QLL+HR+
Sbjct: 47 QLLWHRA 53
>XP_006710750
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QLLFHRS 9
          QLL+HR+
Sbjct: 47 QLLWHRA 53
>XP_006710749
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QLLFHRS 9
          QLL+HR+
Sbjct: 47 QLLWHRA 53
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.347    0.151    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 525,271
Number of extensions: 728
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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