Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           18    1482
NP_000242                                                              18    1482
XP_005264389                                                           18    1482
NP_003741                                                              17    4312
NP_694592                                                              16    5631
NP_694593                                                              16    5631
NP_002028                                                              16    5631
NP_005408                                                              16    5631
NP_938033                                                              16    5631
NP_001036212                                                           16    5631
NP_001036194                                                           16    5631
NP_005239                                                              16    5631
XP_005266949                                                           16    5631
XP_005266947                                                           16    5631
XP_006715492                                                           16    5631
XP_005266946                                                           16    5631
XP_005266945                                                           16    5631
XP_005266944                                                           16    5631
XP_006710515                                                           16    5631
NP_112486                                                              15    9605
>NP_001245210
          Length = 868

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           L QLDAVVS
Sbjct: 533 LAQLDAVVS 541
>NP_000242
          Length = 934

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           L QLDAVVS
Sbjct: 599 LAQLDAVVS 607
>XP_005264389
          Length = 921

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           L QLDAVVS
Sbjct: 599 LAQLDAVVS 607
>NP_003741
          Length = 1382

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQLD+ +S
Sbjct: 234 LVQLDSAIS 242
>NP_694592
          Length = 534

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 323 LVQLYAVVS 331
>NP_694593
          Length = 482

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 271 LVQLYAVVS 279
>NP_002028
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 326 LVQLYAVVS 334
>NP_005408
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 325 LVQLYAVVS 333
>NP_938033
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 325 LVQLYAVVS 333
>NP_001036212
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 318 LVQLYAVVS 326
>NP_001036194
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 318 LVQLYAVVS 326
>NP_005239
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 318 LVQLYAVVS 326
>XP_005266949
          Length = 482

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 271 LVQLYAVVS 279
>XP_005266947
          Length = 534

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 323 LVQLYAVVS 331
>XP_006715492
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 326 LVQLYAVVS 334
>XP_005266946
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 326 LVQLYAVVS 334
>XP_005266945
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 326 LVQLYAVVS 334
>XP_005266944
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 326 LVQLYAVVS 334
>XP_006710515
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           LVQL AVVS
Sbjct: 318 LVQLYAVVS 326
>NP_112486
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVQLDAVVS 9
           ++QLD VVS
Sbjct: 155 IMQLDDVVS 163
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.135    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 290,400
Number of extensions: 271
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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