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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           21     229
NP_004561                                                              21     229
NP_001275703                                                           21     229
XP_005253450                                                           21     229
XP_006719151                                                           21     229
NP_659482                                                              17    3301
XP_005272029                                                           17    3301
NP_775954                                                              17    4312
NP_004516                                                              16    7355
XP_006712590                                                           16    7355
XP_006712589                                                           16    7355
NP_065076                                                              15    9605
NP_005392                                                              15    9605
NP_001123990                                                           15    9605
NP_060841                                                              15    9605
NP_056076                                                              15    9605
NP_997294                                                              15    9605
XP_006723662                                                           15    9605
XP_005260825                                                           15    9605
XP_006723661                                                           15    9605
XP_006716429                                                           15    9605
XP_006716427                                                           15    9605
XP_006716426                                                           15    9605
XP_006716425                                                           15    9605
XP_006716424                                                           15    9605
XP_006716423                                                           15    9605
XP_006716422                                                           15    9605
XP_006716421                                                           15    9605

>NP_001275701
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQAVMFEW 9
           LVQAV FEW
Sbjct: 801 LVQAVKFEW 809



>NP_004561
          Length = 1445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQAVMFEW 9
           LVQAV FEW
Sbjct: 760 LVQAVKFEW 768



>NP_001275703
          Length = 1264

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQAVMFEW 9
           LVQAV FEW
Sbjct: 579 LVQAVKFEW 587



>XP_005253450
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQAVMFEW 9
           LVQAV FEW
Sbjct: 801 LVQAVKFEW 809



>XP_006719151
          Length = 1486

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVQAVMFEW 9
           LVQAV FEW
Sbjct: 801 LVQAVKFEW 809



>NP_659482
          Length = 595

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVQAVMFEW 9
           +VQAV+ EW
Sbjct: 127 VVQAVIREW 135



>XP_005272029
          Length = 213

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   VQAVMFEW 9
           VQAV F W
Sbjct: 184 VQAVSFTW 191



>NP_775954
          Length = 641

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LVQAVMFEW 9
           LVQ++ F W
Sbjct: 175 LVQSLSFRW 183



>NP_004516
          Length = 4655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    VQAVMFEW 9
            +QAV ++W
Sbjct: 4084 IQAVDYDW 4091



>XP_006712590
          Length = 3897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    VQAVMFEW 9
            +QAV ++W
Sbjct: 3326 IQAVDYDW 3333



>XP_006712589
          Length = 4660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    VQAVMFEW 9
            +QAV ++W
Sbjct: 4089 IQAVDYDW 4096



>NP_065076
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   LVQAVMFEW 9
           ++QA   EW
Sbjct: 220 VIQAASLEW 228



>NP_005392
          Length = 1187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   QAVMFEW 9
           QAV++ W
Sbjct: 248 QAVIYRW 254



>NP_001123990
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>NP_060841
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>NP_056076
          Length = 1498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LVQAVMFE 8
           LVQ +MF+
Sbjct: 444 LVQEIMFD 451



>NP_997294
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LVQAVMFEW 9
          LVQA+ + W
Sbjct: 48 LVQALSYLW 56



>XP_006723662
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   LVQAVMFEW 9
           ++QA   EW
Sbjct: 220 VIQAASLEW 228



>XP_005260825
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   LVQAVMFEW 9
           ++QA   EW
Sbjct: 220 VIQAASLEW 228



>XP_006723661
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   LVQAVMFEW 9
           ++QA   EW
Sbjct: 220 VIQAASLEW 228



>XP_006716429
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>XP_006716427
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>XP_006716426
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>XP_006716425
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>XP_006716424
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>XP_006716423
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>XP_006716422
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



>XP_006716421
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QAVMFEW 9
          QAV+ EW
Sbjct: 58 QAVLQEW 64



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.135    0.499 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 277,999
Number of extensions: 203
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)