Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              18    1935
NP_001120972                                                           18    1935
XP_006716052                                                           18    1935
XP_006716051                                                           18    1935
NP_001008539                                                           17    4312
NP_001158243                                                           17    4312
NP_003037                                                              17    4312
XP_005273669                                                           17    4312
XP_005273668                                                           17    4312
XP_005273667                                                           17    4312
XP_006716452                                                           17    4312
XP_005273666                                                           17    4312
NP_060356                                                              16    5631
NP_079062                                                              16    5631
XP_006726480                                                           16    5631
XP_003118580                                                           16    5631
XP_005248429                                                           16    5631
XP_006714562                                                           16    5631
XP_005248426                                                           16    5631
XP_005265319                                                           16    5631
XP_006713278                                                           16    5631
XP_005265318                                                           16    5631
XP_006710228                                                           16    5631
NP_849150                                                              16    7355
NP_062550                                                              15    9605
NP_060164                                                              15    9605
XP_005246713                                                           15    9605
XP_005246712                                                           15    9605
XP_005246711                                                           15    9605
>NP_000236
          Length = 1390

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVLLFILVQ 9
          LVLLF LVQ
Sbjct: 12 LVLLFTLVQ 20
>NP_001120972
          Length = 1408

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVLLFILVQ 9
          LVLLF LVQ
Sbjct: 12 LVLLFTLVQ 20
>XP_006716052
          Length = 1409

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVLLFILVQ 9
          LVLLF LVQ
Sbjct: 31 LVLLFTLVQ 39
>XP_006716051
          Length = 1427

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LVLLFILVQ 9
          LVLLF LVQ
Sbjct: 31 LVLLFTLVQ 39
>NP_001008539
          Length = 658

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLLF++V
Sbjct: 200 LVLLFVMV 207
>NP_001158243
          Length = 698

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLLF++V
Sbjct: 240 LVLLFVMV 247
>NP_003037
          Length = 697

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLLF++V
Sbjct: 240 LVLLFVMV 247
>XP_005273669
          Length = 658

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLLF++V
Sbjct: 200 LVLLFVMV 207
>XP_005273668
          Length = 658

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLLF++V
Sbjct: 200 LVLLFVMV 207
>XP_005273667
          Length = 658

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLLF++V
Sbjct: 200 LVLLFVMV 207
>XP_006716452
          Length = 676

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLLF++V
Sbjct: 219 LVLLFVMV 226
>XP_005273666
          Length = 677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLLF++V
Sbjct: 219 LVLLFVMV 226
>NP_060356
          Length = 1275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLL+IL+
Sbjct: 754 LVLLYILI 761
>NP_079062
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLLFILVQ 9
           +LL++LVQ
Sbjct: 187 ILLYVLVQ 194
>XP_006726480
          Length = 653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLLFILVQ 9
           +LL++LVQ
Sbjct: 432 ILLYVLVQ 439
>XP_003118580
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLLFILVQ 9
           +LL++LVQ
Sbjct: 187 ILLYVLVQ 194
>XP_005248429
          Length = 210

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLLFILVQ 9
           +LL++LVQ
Sbjct: 187 ILLYVLVQ 194
>XP_006714562
          Length = 214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLLFILVQ 9
           +LL++LVQ
Sbjct: 187 ILLYVLVQ 194
>XP_005248426
          Length = 412

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLLFILVQ 9
           +LL++LVQ
Sbjct: 187 ILLYVLVQ 194
>XP_005265319
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLL+IL+
Sbjct: 754 LVLLYILI 761
>XP_006713278
          Length = 1156

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLL+IL+
Sbjct: 635 LVLLYILI 642
>XP_005265318
          Length = 1274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LVLLFILV 8
           LVLL+IL+
Sbjct: 753 LVLLYILI 760
>XP_006710228
          Length = 598

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLLFILVQ 9
           +LL++LVQ
Sbjct: 377 ILLYVLVQ 384
>NP_849150
          Length = 1445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LVLLFILV 8
          LVLLF+L+
Sbjct: 76 LVLLFLLL 83
>NP_062550
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LVLLFILVQ 9
           + +LFI+VQ
Sbjct: 298 IFILFIIVQ 306
>NP_060164
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LVLLFILVQ 9
           ++LLF L+Q
Sbjct: 613 ILLLFALIQ 621
>XP_005246713
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LVLLFILVQ 9
           ++LLF L+Q
Sbjct: 613 ILLLFALIQ 621
>XP_005246712
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LVLLFILVQ 9
           ++LLF L+Q
Sbjct: 613 ILLLFALIQ 621
>XP_005246711
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LVLLFILVQ 9
           ++LLF L+Q
Sbjct: 613 ILLLFALIQ 621
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.360    0.177    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 322,645
Number of extensions: 575
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.0 bits)
S2: 28 (15.4 bits)

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