Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              19     869
NP_001091680                                                           19     869
NP_001091679                                                           19     869
XP_006713048                                                           19     869
XP_006713047                                                           19     869
XP_006713046                                                           19     869
XP_005264943                                                           19     869
NP_002221                                                              18    1482
NP_068831                                                              18    1482
XP_006721941                                                           18    1482
XP_006721940                                                           18    1482
XP_006721939                                                           18    1482
XP_006721938                                                           18    1482
XP_006721937                                                           18    1482
XP_006721936                                                           18    1482
XP_006721935                                                           18    1482
XP_006721934                                                           18    1482
XP_005257370                                                           18    1482
NP_057095                                                              17    2528
XP_005245942                                                           17    2528
NP_001120680                                                           16    5631
NP_054790                                                              16    5631
XP_006723818                                                           16    5631
XP_006723817                                                           16    5631
XP_006723816                                                           16    5631
XP_006723815                                                           16    5631
XP_006723814                                                           16    5631
XP_006723813                                                           16    5631
XP_005260405                                                           16    5631
XP_006714305                                                           16    5631
XP_005263139                                                           16    5631
NP_001275661                                                           16    7355
NP_060939                                                              16    7355
NP_001275662                                                           16    7355
XP_005257564                                                           16    7355
XP_005257608                                                           15    9605
XP_005257606                                                           15    9605



>NP_001895
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVKMLASPV 9
           LVKML SPV
Sbjct: 240 LVKMLGSPV 248





>NP_001091680
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVKMLASPV 9
           LVKML SPV
Sbjct: 240 LVKMLGSPV 248





>NP_001091679
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVKMLASPV 9
           LVKML SPV
Sbjct: 240 LVKMLGSPV 248





>XP_006713048
          Length = 720

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVKMLASPV 9
           LVKML SPV
Sbjct: 240 LVKMLGSPV 248





>XP_006713047
          Length = 774

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVKMLASPV 9
           LVKML SPV
Sbjct: 233 LVKMLGSPV 241





>XP_006713046
          Length = 774

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVKMLASPV 9
           LVKML SPV
Sbjct: 233 LVKMLGSPV 241





>XP_005264943
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LVKMLASPV 9
           LVKML SPV
Sbjct: 240 LVKMLGSPV 248





>NP_002221
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 231 LVRMLSSPV 239





>NP_068831
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 231 LVRMLSSPV 239





>XP_006721941
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 231 LVRMLSSPV 239





>XP_006721940
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 231 LVRMLSSPV 239





>XP_006721939
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 231 LVRMLSSPV 239





>XP_006721938
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 231 LVRMLSSPV 239





>XP_006721937
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 231 LVRMLSSPV 239





>XP_006721936
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 231 LVRMLSSPV 239





>XP_006721935
          Length = 762

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 248 LVRMLSSPV 256





>XP_006721934
          Length = 783

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 269 LVRMLSSPV 277





>XP_005257370
          Length = 783

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   LVKMLASPV 9
           LV+ML+SPV
Sbjct: 269 LVRMLSSPV 277





>NP_057095
          Length = 373

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VKMLASPV 9
          VKMLA+P+
Sbjct: 75 VKMLAAPI 82





>XP_005245942
          Length = 401

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VKMLASPV 9
           VKMLA+P+
Sbjct: 103 VKMLAAPI 110





>NP_001120680
          Length = 2002

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    VKMLASPV 9
            V+MLA PV
Sbjct: 1454 VRMLAEPV 1461





>NP_054790
          Length = 2063

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVKMLASPV 9
            L+KM +SPV
Sbjct: 1886 LLKMTSSPV 1894





>XP_006723818
          Length = 1975

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVKMLASPV 9
            L+KM +SPV
Sbjct: 1886 LLKMTSSPV 1894





>XP_006723817
          Length = 2020

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVKMLASPV 9
            L+KM +SPV
Sbjct: 1843 LLKMTSSPV 1851





>XP_006723816
          Length = 2034

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVKMLASPV 9
            L+KM +SPV
Sbjct: 1886 LLKMTSSPV 1894





>XP_006723815
          Length = 2051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVKMLASPV 9
            L+KM +SPV
Sbjct: 1874 LLKMTSSPV 1882





>XP_006723814
          Length = 2052

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVKMLASPV 9
            L+KM +SPV
Sbjct: 1875 LLKMTSSPV 1883





>XP_006723813
          Length = 2062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVKMLASPV 9
            L+KM +SPV
Sbjct: 1886 LLKMTSSPV 1894





>XP_005260405
          Length = 2063

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LVKMLASPV 9
            L+KM +SPV
Sbjct: 1886 LLKMTSSPV 1894





>XP_006714305
          Length = 1902

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    VKMLASPV 9
            V+MLA PV
Sbjct: 1354 VRMLAEPV 1361





>XP_005263139
          Length = 2002

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    VKMLASPV 9
            V+MLA PV
Sbjct: 1454 VRMLAEPV 1461





>NP_001275661
          Length = 1127

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VKMLASPV 9
           VK+L SPV
Sbjct: 114 VKLLESPV 121





>NP_060939
          Length = 1134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VKMLASPV 9
           VK+L SPV
Sbjct: 114 VKLLESPV 121





>NP_001275662
          Length = 1127

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VKMLASPV 9
           VK+L SPV
Sbjct: 114 VKLLESPV 121





>XP_005257564
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VKMLASPV 9
           VK+L SPV
Sbjct: 114 VKLLESPV 121





>XP_005257608
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LVKMLASP 8
           L+K LA+P
Sbjct: 136 LIKFLANP 143





>XP_005257606
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LVKMLASP 8
           L+K LA+P
Sbjct: 208 LIKFLANP 215





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.133    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 542,527
Number of extensions: 497
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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