Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     390
NP_001075109                                                           20     390
NP_078959                                                              17    2528
XP_006722147                                                           17    2528
NP_079160                                                              17    3301
XP_005268134                                                           17    3301
XP_005268132                                                           17    3301
NP_000487                                                              17    4312
NP_006332                                                              17    4312
XP_006724204                                                           17    4312
XP_005263480                                                           17    4312
NP_001120797                                                           17    4312
NP_055504                                                              16    5631
NP_001277192                                                           16    5631
NP_055325                                                              16    5631
NP_149015                                                              16    5631
NP_006504                                                              16    5631
XP_006715989                                                           16    5631
XP_005249902                                                           16    5631
XP_006712687                                                           16    5631
XP_006712686                                                           16    5631
XP_006712685                                                           16    5631
XP_006712684                                                           16    5631
XP_006712683                                                           16    5631
XP_006712682                                                           16    5631
XP_006712681                                                           16    5631
XP_005246730                                                           16    5631
XP_005246729                                                           16    5631
XP_006712680                                                           16    5631
XP_006712679                                                           16    5631
XP_006710876                                                           16    5631
NP_076972                                                              16    5631
NP_775827                                                              16    7355
XP_005273899                                                           16    7355
XP_006718532                                                           16    7355
XP_006718531                                                           16    7355
NP_001273088                                                           16    7355
NP_112503                                                              15    9605
NP_000094                                                              15    9605
NP_060222                                                              15    9605
NP_056327                                                              15    9605
NP_001193581                                                           15    9605
NP_057093                                                              15    9605
NP_001193580                                                           15    9605
NP_067068                                                              15    9605
NP_203748                                                              15    9605
NP_001268861                                                           15    9605
NP_060230                                                              15    9605
XP_006724733                                                           15    9605
XP_006724732                                                           15    9605
XP_006720469                                                           15    9605
XP_005254249                                                           15    9605
XP_005254248                                                           15    9605
XP_005254247                                                           15    9605
XP_005271772                                                           15    9605
XP_005249604                                                           15    9605
XP_006713163                                                           15    9605
XP_006710735                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LVEQFVFES 9
            LVEQFVFE+
Sbjct: 1095 LVEQFVFEA 1103
>NP_001075109
          Length = 4097

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LVEQFVFES 9
            LVEQFVFE+
Sbjct: 1095 LVEQFVFEA 1103
>NP_078959
          Length = 360

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LVEQFVFES 9
           LV+QF+F+S
Sbjct: 299 LVKQFLFDS 307
>XP_006722147
          Length = 245

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LVEQFVFES 9
           LV+QF+F+S
Sbjct: 184 LVKQFLFDS 192
>NP_079160
          Length = 463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           LVE FVF++
Sbjct: 415 LVEDFVFDA 423
>XP_005268134
          Length = 281

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           LVE FVF++
Sbjct: 233 LVEDFVFDA 241
>XP_005268132
          Length = 463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           LVE FVF++
Sbjct: 415 LVEDFVFDA 423
>NP_000487
          Length = 205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  EQFVFE 8
          EQFVFE
Sbjct: 70 EQFVFE 75
>NP_006332
          Length = 211

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VEQFVFE 8
           VE+FVFE
Sbjct: 95  VEKFVFE 101
>XP_006724204
          Length = 205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  EQFVFE 8
          EQFVFE
Sbjct: 70 EQFVFE 75
>XP_005263480
          Length = 276

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VEQFVFE 8
           VE+FVFE
Sbjct: 160 VEKFVFE 166
>NP_001120797
          Length = 211

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VEQFVFE 8
           VE+FVFE
Sbjct: 95  VEKFVFE 101
>NP_055504
          Length = 2186

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 654 VEEFVYDS 661
>NP_001277192
          Length = 2180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 648 VEEFVYDS 655
>NP_055325
          Length = 4935

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LVEQFVFES 9
            L+E +++ES
Sbjct: 1951 LIEDYIYES 1959
>NP_149015
          Length = 5142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LVEQFVFES 9
            L+E +++ES
Sbjct: 1951 LIEDYIYES 1959
>NP_006504
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEQFVFES 9
           +EQFV+ S
Sbjct: 324 IEQFVYSS 331
>XP_006715989
          Length = 5148

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    LVEQFVFES 9
            L+E +++ES
Sbjct: 1951 LIEDYIYES 1959
>XP_005249902
          Length = 589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LVEQFVFE 8
          L+E+FVF+
Sbjct: 47 LLEEFVFQ 54
>XP_006712687
          Length = 2166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_006712686
          Length = 2173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_006712685
          Length = 2175

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_006712684
          Length = 2189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 648 VEEFVYDS 655
>XP_006712683
          Length = 2195

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 654 VEEFVYDS 661
>XP_006712682
          Length = 2199

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_006712681
          Length = 2199

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_005246730
          Length = 2199

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_005246729
          Length = 2201

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_006712680
          Length = 2206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_006712679
          Length = 2208

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEQFVFES 9
           VE+FV++S
Sbjct: 667 VEEFVYDS 674
>XP_006710876
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VEQFVFES 9
           +EQFV+ S
Sbjct: 324 IEQFVYSS 331
>NP_076972
          Length = 449

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LVEQFVFE 8
          L+E+FVF+
Sbjct: 47 LLEEFVFQ 54
>NP_775827
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          VEQF+F+
Sbjct: 40 VEQFMFQ 46
>XP_005273899
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          VEQF+F+
Sbjct: 40 VEQFMFQ 46
>XP_006718532
          Length = 413

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          VEQF+F+
Sbjct: 40 VEQFMFQ 46
>XP_006718531
          Length = 413

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          VEQF+F+
Sbjct: 40 VEQFMFQ 46
>NP_001273088
          Length = 413

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          VEQF+F+
Sbjct: 40 VEQFMFQ 46
>NP_112503
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           ++E F++ES
Sbjct: 355 VMENFIYES 363
>NP_000094
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           ++E F++ES
Sbjct: 355 VMENFIYES 363
>NP_060222
          Length = 1120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVEQFVFE 8
           LV+Q VFE
Sbjct: 615 LVDQAVFE 622
>NP_056327
          Length = 4265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    VEQFVFE 8
            VE+F+FE
Sbjct: 1661 VERFMFE 1667
>NP_001193581
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          +E+FV+E
Sbjct: 75 IEEFVYE 81
>NP_057093
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          +E+FV+E
Sbjct: 75 IEEFVYE 81
>NP_001193580
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          +E+FV+E
Sbjct: 75 IEEFVYE 81
>NP_067068
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  VEQFVFES 9
          VE+F++E+
Sbjct: 67 VEKFIYEN 74
>NP_203748
          Length = 883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EQFVFES 9
           EQF F+S
Sbjct: 805 EQFTFQS 811
>NP_001268861
          Length = 1143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    VEQFVFES 9
            +E+F++ES
Sbjct: 1125 IERFLYES 1132
>NP_060230
          Length = 1143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    VEQFVFES 9
            +E+F++ES
Sbjct: 1125 IERFLYES 1132
>XP_006724733
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVEQFVFE 8
           LV+Q VFE
Sbjct: 517 LVDQAVFE 524
>XP_006724732
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LVEQFVFE 8
           LV+Q VFE
Sbjct: 565 LVDQAVFE 572
>XP_006720469
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           ++E F++ES
Sbjct: 253 VMENFIYES 261
>XP_005254249
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           ++E F++ES
Sbjct: 296 VMENFIYES 304
>XP_005254248
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           ++E F++ES
Sbjct: 355 VMENFIYES 363
>XP_005254247
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LVEQFVFES 9
           ++E F++ES
Sbjct: 355 VMENFIYES 363
>XP_005271772
          Length = 884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EQFVFES 9
           EQF F+S
Sbjct: 806 EQFTFQS 812
>XP_005249604
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    VEQFVFES 9
            +E+F++ES
Sbjct: 1078 IERFLYES 1085
>XP_006713163
          Length = 4265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    VEQFVFE 8
            VE+F+FE
Sbjct: 1661 VERFMFE 1667
>XP_006710735
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  VEQFVFE 8
          +E+FV+E
Sbjct: 75 IEEFVYE 81
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.143    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 418,714
Number of extensions: 641
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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