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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     665
NP_009297                                                              19     665
NP_001268639                                                           16    5631
NP_001268640                                                           16    5631
NP_056156                                                              16    5631
NP_001268641                                                           16    5631
XP_006712451                                                           16    5631
XP_005263965                                                           16    5631
XP_005263964                                                           16    5631
NP_775922                                                              16    7355
NP_001188386                                                           15    9605
NP_938207                                                              15    9605
NP_112562                                                              15    9605
NP_068657                                                              15    9605
NP_000499                                                              15    9605
NP_872286                                                              15    9605
NP_055949                                                              15    9605
NP_958431                                                              15    9605
NP_872282                                                              15    9605
XP_006722041                                                           15    9605
XP_005257576                                                           15    9605
XP_006722040                                                           15    9605
XP_006722039                                                           15    9605
XP_005257575                                                           15    9605
XP_005256621                                                           15    9605
XP_006721553                                                           15    9605
XP_006721552                                                           15    9605
XP_006721551                                                           15    9605
XP_006721550                                                           15    9605
XP_005256620                                                           15    9605
XP_005267776                                                           15    9605
XP_005267775                                                           15    9605
XP_006720219                                                           15    9605
XP_005267773                                                           15    9605

>NP_005148
          Length = 1130

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LVDAVNSD 8
           LVDAVNSD
Sbjct: 937 LVDAVNSD 944



>NP_009297
          Length = 1149

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LVDAVNSD 8
           LVDAVNSD
Sbjct: 956 LVDAVNSD 963



>NP_001268639
          Length = 730

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDAVNSDV 9
           VDAV++DV
Sbjct: 158 VDAVHADV 165



>NP_001268640
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDAVNSDV 9
           VDAV++DV
Sbjct: 145 VDAVHADV 152



>NP_056156
          Length = 741

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDAVNSDV 9
           VDAV++DV
Sbjct: 169 VDAVHADV 176



>NP_001268641
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  VDAVNSDV 9
          VDAV++DV
Sbjct: 33 VDAVHADV 40



>XP_006712451
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDAVNSDV 9
           VDAV++DV
Sbjct: 169 VDAVHADV 176



>XP_005263965
          Length = 725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDAVNSDV 9
           VDAV++DV
Sbjct: 169 VDAVHADV 176



>XP_005263964
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VDAVNSDV 9
           VDAV++DV
Sbjct: 166 VDAVHADV 173



>NP_775922
          Length = 6996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    LVDAVNSDV 9
            ++DAV+SD+
Sbjct: 1775 ILDAVSSDM 1783



>NP_001188386
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VDAVNS 7
          VDAVNS
Sbjct: 49 VDAVNS 54



>NP_938207
          Length = 1491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VDAVNS 7
          VDAVNS
Sbjct: 49 VDAVNS 54



>NP_112562
          Length = 1451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VDAVNS 7
          VDAVNS
Sbjct: 49 VDAVNS 54



>NP_068657
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  LVDAVNSD 8
          L+D VN D
Sbjct: 73 LIDEVNQD 80



>NP_000499
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  LVDAVNSD 8
          L+D VN D
Sbjct: 73 LIDEVNQD 80



>NP_872286
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VDAVNS 7
           VDAVNS
Sbjct: 265 VDAVNS 270



>NP_055949
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VDAVNSDV 9
           + +VNSDV
Sbjct: 795 ISSVNSDV 802



>NP_958431
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VDAVNSDV 9
           + +VNSDV
Sbjct: 795 ISSVNSDV 802



>NP_872282
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VDAVNS 7
           VDAVNS
Sbjct: 290 VDAVNS 295



>XP_006722041
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VDAVNS 7
          VDAVNS
Sbjct: 52 VDAVNS 57



>XP_005257576
          Length = 1454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VDAVNS 7
          VDAVNS
Sbjct: 52 VDAVNS 57



>XP_006722040
          Length = 1466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VDAVNS 7
          VDAVNS
Sbjct: 52 VDAVNS 57



>XP_006722039
          Length = 1491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VDAVNS 7
          VDAVNS
Sbjct: 49 VDAVNS 54



>XP_005257575
          Length = 1494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VDAVNS 7
          VDAVNS
Sbjct: 52 VDAVNS 57



>XP_005256621
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VDAVNSDV 9
           + +VNSDV
Sbjct: 789 ISSVNSDV 796



>XP_006721553
          Length = 2286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VDAVNSDV 9
            + +VNSDV
Sbjct: 2096 ISSVNSDV 2103



>XP_006721552
          Length = 2299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VDAVNSDV 9
            + +VNSDV
Sbjct: 2096 ISSVNSDV 2103



>XP_006721551
          Length = 2301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VDAVNSDV 9
            + +VNSDV
Sbjct: 2058 ISSVNSDV 2065



>XP_006721550
          Length = 2326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VDAVNSDV 9
            + +VNSDV
Sbjct: 2096 ISSVNSDV 2103



>XP_005256620
          Length = 2339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VDAVNSDV 9
            + +VNSDV
Sbjct: 2096 ISSVNSDV 2103



>XP_005267776
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VDAVNS 7
           VDAVNS
Sbjct: 110 VDAVNS 115



>XP_005267775
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VDAVNS 7
           VDAVNS
Sbjct: 110 VDAVNS 115



>XP_006720219
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VDAVNS 7
           VDAVNS
Sbjct: 181 VDAVNS 186



>XP_005267773
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VDAVNS 7
           VDAVNS
Sbjct: 235 VDAVNS 240



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.129    0.321 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 423,846
Number of extensions: 856
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)