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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1482
NP_001075109                                                           18    1482
NP_002934                                                              17    4312
NP_031401                                                              16    5631
NP_004163                                                              16    5631
NP_036312                                                              16    5631
NP_001257545                                                           16    5631
NP_001180291                                                           16    5631
NP_001180290                                                           16    5631
NP_001180289                                                           16    5631
NP_001180292                                                           16    5631
NP_001160167                                                           16    5631
NP_001276868                                                           16    5631
NP_002754                                                              16    5631
NP_060669                                                              16    5631
XP_005267875                                                           16    5631
XP_005267874                                                           16    5631
XP_006720253                                                           16    5631
XP_006714551                                                           16    5631
XP_005248399                                                           16    5631
XP_005273252                                                           16    5631
XP_005273253                                                           16    5631
XP_005273251                                                           16    5631
NP_001243034                                                           15    9605
NP_003383                                                              15    9605
NP_055979                                                              15    9605
XP_006713387                                                           15    9605
XP_005245848                                                           15    9605
XP_005245847                                                           15    9605

>NP_008835
          Length = 4128

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVALREFFS 9
            L ALREFFS
Sbjct: 1833 LDALREFFS 1841



>NP_001075109
          Length = 4097

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LVALREFFS 9
            L ALREFFS
Sbjct: 1833 LDALREFFS 1841



>NP_002934
          Length = 548

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VALREFFS 9
          + LREFFS
Sbjct: 75 INLREFFS 82



>NP_031401
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LREFFS 9
           LREFFS
Sbjct: 207 LREFFS 212



>NP_004163
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALREFF 8
           ALREFF
Sbjct: 266 ALREFF 271



>NP_036312
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALREFF 8
           ALREFF
Sbjct: 213 ALREFF 218



>NP_001257545
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VALREFFS 9
           + LREFF+
Sbjct: 687 ITLREFFN 694



>NP_001180291
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVALREFFS 9
           L ALREF++
Sbjct: 524 LQALREFYN 532



>NP_001180290
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVALREFFS 9
           L ALREF++
Sbjct: 524 LQALREFYN 532



>NP_001180289
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVALREFFS 9
           L ALREF++
Sbjct: 524 LQALREFYN 532



>NP_001180292
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVALREFFS 9
           L ALREF++
Sbjct: 524 LQALREFYN 532



>NP_001160167
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALREFF 8
           ALREFF
Sbjct: 266 ALREFF 271



>NP_001276868
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALREFF 8
           ALREFF
Sbjct: 220 ALREFF 225



>NP_002754
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VALREFFS 9
           + LREFF+
Sbjct: 687 ITLREFFN 694



>NP_060669
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVALREFFS 9
           L ALREF++
Sbjct: 399 LQALREFYN 407



>XP_005267875
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVALREFFS 9
           L ALREF++
Sbjct: 269 LQALREFYN 277



>XP_005267874
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVALREFFS 9
           L ALREF++
Sbjct: 399 LQALREFYN 407



>XP_006720253
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LVALREFFS 9
           L ALREF++
Sbjct: 524 LQALREFYN 532



>XP_006714551
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALREFF 8
           ALREFF
Sbjct: 266 ALREFF 271



>XP_005248399
          Length = 542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALREFF 8
           ALREFF
Sbjct: 266 ALREFF 271



>XP_005273252
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VALREFFS 9
           + LREFF+
Sbjct: 688 ITLREFFN 695



>XP_005273253
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VALREFFS 9
           + LREFF+
Sbjct: 688 ITLREFFN 695



>XP_005273251
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VALREFFS 9
           + LREFF+
Sbjct: 688 ITLREFFN 695



>NP_001243034
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVALREFFS 9
          LVAL  FFS
Sbjct: 12 LVALAIFFS 20



>NP_003383
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVALREFFS 9
          LVAL  FFS
Sbjct: 27 LVALAIFFS 35



>NP_055979
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VALREFF 8
           VAL EFF
Sbjct: 688 VALAEFF 694



>XP_006713387
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LVALREFFS 9
          LVAL  FFS
Sbjct: 12 LVALAIFFS 20



>XP_005245848
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VALREFF 8
           VAL EFF
Sbjct: 485 VALAEFF 491



>XP_005245847
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VALREFF 8
           VAL EFF
Sbjct: 668 VALAEFF 674



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.153    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 409,530
Number of extensions: 489
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)