Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              18    1482
NP_001276866                                                           18    1935
NP_004439                                                              18    1935
NP_001276865                                                           18    1935
NP_001005862                                                           18    1935
XP_005257197                                                           18    1935
XP_006721828                                                           18    1935
NP_004501                                                              15    9605
NP_004500                                                              15    9605
NP_536349                                                              15    9605
NP_683865                                                              15    9605
NP_001171944                                                           15    9605
XP_005246584                                                           15    9605
XP_006712552                                                           15    9605
XP_006712551                                                           15    9605
XP_006712550                                                           15    9605
XP_006712549                                                           15    9605
XP_005246582                                                           15    9605
>NP_005219
          Length = 1210

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LTSTVQLI 8
           LTSTVQLI
Sbjct: 782 LTSTVQLI 789
>NP_001276866
          Length = 1055

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LTSTVQLI 8
           LTSTVQL+
Sbjct: 790 LTSTVQLV 797
>NP_004439
          Length = 1255

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LTSTVQLI 8
           LTSTVQL+
Sbjct: 790 LTSTVQLV 797
>NP_001276865
          Length = 1240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LTSTVQLI 8
           LTSTVQL+
Sbjct: 775 LTSTVQLV 782
>NP_001005862
          Length = 1225

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LTSTVQLI 8
           LTSTVQL+
Sbjct: 760 LTSTVQLV 767
>XP_005257197
          Length = 1225

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LTSTVQLI 8
           LTSTVQL+
Sbjct: 760 LTSTVQLV 767
>XP_006721828
          Length = 1336

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LTSTVQLI 8
           LTSTVQL+
Sbjct: 871 LTSTVQLV 878
>NP_004501
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 217 LTSTVQV 223
>NP_004500
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 217 LTSTVQV 223
>NP_536349
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 217 LTSTVQV 223
>NP_683865
          Length = 363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTST+QL
Sbjct: 311 LTSTLQL 317
>NP_001171944
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 223 LTSTVQV 229
>XP_005246584
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LTSTVQL 7
          LTSTVQ+
Sbjct: 14 LTSTVQV 20
>XP_006712552
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 223 LTSTVQV 229
>XP_006712551
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 223 LTSTVQV 229
>XP_006712550
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 223 LTSTVQV 229
>XP_006712549
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 217 LTSTVQV 223
>XP_005246582
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LTSTVQL 7
           LTSTVQ+
Sbjct: 223 LTSTVQV 229
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.130    0.300 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 240,232
Number of extensions: 131
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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