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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1135
NP_001075109                                                           18    1135
NP_001175                                                              16    5631
NP_056057                                                              16    5631
NP_001035207                                                           16    5631
NP_112552                                                              16    7355
NP_112553                                                              16    7355
NP_002131                                                              16    7355
XP_005252023                                                           16    7355
XP_005252022                                                           16    7355
XP_005252020                                                           16    7355
XP_005252021                                                           16    7355
XP_005252018                                                           16    7355
XP_005252017                                                           16    7355
NP_115688                                                              16    7355
NP_000221                                                              15    9605
NP_064592                                                              15    9605
NP_001010895                                                           15    9605
NP_001104268                                                           15    9605
NP_078837                                                              15    9605
NP_004757                                                              15    9605
NP_476516                                                              15    9605
XP_005266579                                                           15    9605
XP_006719929                                                           15    9605
XP_005250397                                                           15    9605
XP_005263293                                                           15    9605

>NP_008835
          Length = 4128

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LTKTLIKL 8
            LTKTLIKL
Sbjct: 1911 LTKTLIKL 1918



>NP_001075109
          Length = 4097

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LTKTLIKL 8
            LTKTLIKL
Sbjct: 1911 LTKTLIKL 1918



>NP_001175
          Length = 2644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LTKTLIKLF 9
           LTK L++LF
Sbjct: 145 LTKELLQLF 153



>NP_056057
          Length = 1205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TKTLIKLF 9
           T+TLI+LF
Sbjct: 353 TETLIELF 360



>NP_001035207
          Length = 1450

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TKTLIKLF 9
           T+TLI+LF
Sbjct: 598 TETLIELF 605



>NP_112552
          Length = 463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 174 TQTTIKLF 181



>NP_112553
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 174 TQTTIKLF 181



>NP_002131
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 174 TQTTIKLF 181



>XP_005252023
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 150 TQTTIKLF 157



>XP_005252022
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 150 TQTTIKLF 157



>XP_005252020
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 150 TQTTIKLF 157



>XP_005252021
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 150 TQTTIKLF 157



>XP_005252018
          Length = 463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 174 TQTTIKLF 181



>XP_005252017
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T+T IKLF
Sbjct: 174 TQTTIKLF 181



>NP_115688
          Length = 244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTKTLIKLF 9
           +  TLIKLF
Sbjct: 193 VVSTLIKLF 201



>NP_000221
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TKTLIK 7
          TKTLIK
Sbjct: 31 TKTLIK 36



>NP_064592
          Length = 1561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TKTLIK 7
           TKTLIK
Sbjct: 383 TKTLIK 388



>NP_001010895
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TKTLIK 7
           TKTLIK
Sbjct: 383 TKTLIK 388



>NP_001104268
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T TLI+LF
Sbjct: 404 TPTLIELF 411



>NP_078837
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T TLI+LF
Sbjct: 404 TPTLIELF 411



>NP_004757
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TKTLIKLF 9
          T+TL+K F
Sbjct: 46 TQTLVKTF 53



>NP_476516
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T TLI+LF
Sbjct: 404 TPTLIELF 411



>XP_005266579
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T TLI+LF
Sbjct: 404 TPTLIELF 411



>XP_006719929
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T TLI+LF
Sbjct: 344 TPTLIELF 351



>XP_005250397
          Length = 166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TKTLIK 7
          TKTLIK
Sbjct: 31 TKTLIK 36



>XP_005263293
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TKTLIKLF 9
           T TLI+LF
Sbjct: 404 TPTLIELF 411



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.151    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 362,376
Number of extensions: 516
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)