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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     869
XP_005266703                                                           19     869
NP_001243779                                                           18    1935
NP_596869                                                              18    1935
XP_006712787                                                           18    1935
XP_006712786                                                           18    1935
NP_001254479                                                           18    1935
NP_056520                                                              17    3301
XP_005276377                                                           17    3301
XP_005261636                                                           17    3301
XP_005261634                                                           17    3301
XP_005261632                                                           17    3301
XP_005261631                                                           17    3301
XP_005261630                                                           17    3301
XP_005261629                                                           17    3301
NP_001229326                                                           17    4312
NP_002813                                                              17    4312
NP_064446                                                              16    5631
NP_001599                                                              16    7355
NP_006759                                                              16    7355
XP_006721518                                                           16    7355
XP_005254001                                                           16    7355
XP_005246574                                                           16    7355
NP_037528                                                              15    9605
NP_001269970                                                           15    9605
NP_001269971                                                           15    9605
NP_699181                                                              15    9605
NP_000276                                                              15    9605
NP_116161                                                              15    9605
NP_079514                                                              15    9605
NP_001011885                                                           15    9605
NP_001159529                                                           15    9605
NP_001159528                                                           15    9605
XP_005261006                                                           15    9605
XP_006724055                                                           15    9605
XP_005255189                                                           15    9605
XP_006720636                                                           15    9605

>NP_443179
          Length = 2170

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LTDVGIETL 9
            LTDVGI TL
Sbjct: 2088 LTDVGIATL 2096



>XP_005266703
          Length = 1501

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LTDVGIETL 9
            LTDVGI TL
Sbjct: 1419 LTDVGIATL 1427



>NP_001243779
          Length = 34350

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LTDVGIE 7
            LTDVGIE
Sbjct: 5286 LTDVGIE 5292



>NP_596869
          Length = 33423

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LTDVGIE 7
            LTDVGIE
Sbjct: 4359 LTDVGIE 4365



>XP_006712787
          Length = 33978

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LTDVGIE 7
            LTDVGIE
Sbjct: 5287 LTDVGIE 5293



>XP_006712786
          Length = 35484

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LTDVGIE 7
            LTDVGIE
Sbjct: 5287 LTDVGIE 5293



>NP_001254479
          Length = 35991

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    LTDVGIE 7
            LTDVGIE
Sbjct: 5603 LTDVGIE 5609



>NP_056520
          Length = 749

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LTDVGIET 8
           LTDV +ET
Sbjct: 361 LTDVAVET 368



>XP_005276377
          Length = 328

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TDVGIET 8
          TD+G+ET
Sbjct: 23 TDIGLET 29



>XP_005261636
          Length = 596

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LTDVGIET 8
           LTDV +ET
Sbjct: 294 LTDVAVET 301



>XP_005261634
          Length = 632

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LTDVGIET 8
           LTDV +ET
Sbjct: 361 LTDVAVET 368



>XP_005261632
          Length = 699

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LTDVGIET 8
           LTDV +ET
Sbjct: 294 LTDVAVET 301



>XP_005261631
          Length = 739

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LTDVGIET 8
           LTDV +ET
Sbjct: 361 LTDVAVET 368



>XP_005261630
          Length = 756

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LTDVGIET 8
           LTDV +ET
Sbjct: 361 LTDVAVET 368



>XP_005261629
          Length = 766

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LTDVGIET 8
           LTDV +ET
Sbjct: 361 LTDVAVET 368



>NP_001229326
          Length = 357

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TDVGIET 8
           TDVG++T
Sbjct: 171 TDVGVDT 177



>NP_002813
          Length = 350

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TDVGIET 8
           TDVG++T
Sbjct: 164 TDVGVDT 170



>NP_064446
          Length = 387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DVGIETL 9
           DVG++TL
Sbjct: 247 DVGVDTL 253



>NP_001599
          Length = 430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LTDVGIETL 9
          LTD+GI  +
Sbjct: 44 LTDIGIRRI 52



>NP_006759
          Length = 592

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LTDVGIETL 9
          +TDV IET+
Sbjct: 69 MTDVIIETM 77



>XP_006721518
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LTDVGI 6
           LTDVGI
Sbjct: 339 LTDVGI 344



>XP_005254001
          Length = 633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LTDVGIETL 9
           +TDV IET+
Sbjct: 110 MTDVIIETM 118



>XP_005246574
          Length = 409

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LTDVGIETL 9
          LTD+GI  +
Sbjct: 23 LTDIGIRRI 31



>NP_037528
          Length = 1055

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGIETL 9
           VGIETL
Sbjct: 676 VGIETL 681



>NP_001269970
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGIETL 9
           VGIETL
Sbjct: 676 VGIETL 681



>NP_001269971
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGIETL 9
           VGIETL
Sbjct: 676 VGIETL 681



>NP_699181
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   LTDVGIETL 9
           +TD G+E +
Sbjct: 205 ITDAGLEVM 213



>NP_000276
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTDVGIETL 9
           +TD GIE L
Sbjct: 457 VTDSGIELL 465



>NP_116161
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   LTDVGIE 7
           L+D+G+E
Sbjct: 164 LSDIGVE 170



>NP_079514
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TDVGIETL 9
           TD+ I+TL
Sbjct: 217 TDIDIDTL 224



>NP_001011885
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TDVGIETL 9
           TD+ I+TL
Sbjct: 217 TDIDIDTL 224



>NP_001159529
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTDVGIETL 9
           +TD GIE L
Sbjct: 393 VTDSGIELL 401



>NP_001159528
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTDVGIETL 9
           +TD GIE L
Sbjct: 416 VTDSGIELL 424



>XP_005261006
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGIETL 9
           VGIETL
Sbjct: 272 VGIETL 277



>XP_006724055
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VGIETL 9
           VGIETL
Sbjct: 377 VGIETL 382



>XP_005255189
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   LTDVGIETL 9
           +TD G+E +
Sbjct: 205 ITDAGLEVM 213



>XP_006720636
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TDVGIETL 9
           TD+ I+TL
Sbjct: 217 TDIDIDTL 224



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.142    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 456,440
Number of extensions: 649
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)