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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001229819                                                           18    1482
NP_473373                                                              17    2528
NP_001276866                                                           17    3301
NP_004439                                                              17    3301
NP_001276865                                                           17    3301
NP_001005862                                                           17    3301
NP_671732                                                              17    3301
NP_473372                                                              17    3301
XP_005257197                                                           17    3301
XP_006721828                                                           17    3301
NP_071936                                                              16    5631
NP_150094                                                              16    7355
NP_689585                                                              16    7355
NP_065117                                                              16    7355
NP_695006                                                              16    7355
NP_001164563                                                           16    7355
NP_001164566                                                           16    7355
XP_005270805                                                           16    7355
NP_000432                                                              15    9605
NP_976046                                                              15    9605
NP_001127666                                                           15    9605
NP_899063                                                              15    9605
NP_001254505                                                           15    9605
NP_694942                                                              15    9605
XP_005250483                                                           15    9605
XP_006716087                                                           15    9605
XP_005250482                                                           15    9605

>NP_001229819
          Length = 338

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TCIISAVV 9
           TC++SAVV
Sbjct: 328 TCLVSAVV 335



>NP_473373
          Length = 322

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  LTCIISAV 8
          LTCIIS V
Sbjct: 33 LTCIISLV 40



>NP_001276866
          Length = 1055

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LTCIISAVV 9
           LT IISAVV
Sbjct: 651 LTSIISAVV 659



>NP_004439
          Length = 1255

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LTCIISAVV 9
           LT IISAVV
Sbjct: 651 LTSIISAVV 659



>NP_001276865
          Length = 1240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LTCIISAVV 9
           LT IISAVV
Sbjct: 636 LTSIISAVV 644



>NP_001005862
          Length = 1225

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LTCIISAVV 9
           LT IISAVV
Sbjct: 621 LTSIISAVV 629



>NP_671732
          Length = 322

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LTCIISAV 8
          LTCI+S V
Sbjct: 33 LTCIVSLV 40



>NP_473372
          Length = 322

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LTCIISAV 8
          LTCI+S V
Sbjct: 33 LTCIVSLV 40



>XP_005257197
          Length = 1225

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LTCIISAVV 9
           LT IISAVV
Sbjct: 621 LTSIISAVV 629



>XP_006721828
          Length = 1336

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LTCIISAVV 9
           LT IISAVV
Sbjct: 732 LTSIISAVV 740



>NP_071936
          Length = 328

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LTCIISAV 8
           L+C+IS+V
Sbjct: 285 LSCVISSV 292



>NP_150094
          Length = 3564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LTCIIS 6
           LTCI+S
Sbjct: 183 LTCIVS 188



>NP_689585
          Length = 1437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    LTCIIS 6
            LTCI+S
Sbjct: 1354 LTCIVS 1359



>NP_065117
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LTCIISAV 8
           L CIIS V
Sbjct: 93  LACIISVV 100



>NP_695006
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTCIISAVV 9
           L C+ISA V
Sbjct: 106 LMCVISASV 114



>NP_001164563
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LTCIISAV 8
           L CIIS V
Sbjct: 93  LACIISVV 100



>NP_001164566
          Length = 230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LTCIISAV 8
           L CIIS V
Sbjct: 93  LACIISVV 100



>XP_005270805
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LTCIISAVV 9
           L C+ISA V
Sbjct: 106 LMCVISASV 114



>NP_000432
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TCIISAVV 9
           TCI+S ++
Sbjct: 485 TCIVSIIL 492



>NP_976046
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   LTCIISAVV 9
           +TC+  A+V
Sbjct: 403 ITCVSGAIV 411



>NP_001127666
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   CIISAVV 9
           C+ISAV+
Sbjct: 390 CLISAVL 396



>NP_899063
          Length = 190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LTCIISAVV 9
          +TC+  AVV
Sbjct: 31 ITCVALAVV 39



>NP_001254505
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCIISAVV 9
           TC ++AVV
Sbjct: 109 TCFMNAVV 116



>NP_694942
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TCIISAVV 9
           TC ++AVV
Sbjct: 109 TCFMNAVV 116



>XP_005250483
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  TCIISAVV 9
          TCI+S ++
Sbjct: 72 TCIVSIIL 79



>XP_006716087
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TCIISAVV 9
           TCI+S ++
Sbjct: 485 TCIVSIIL 492



>XP_005250482
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   TCIISAVV 9
           TCI+S ++
Sbjct: 485 TCIVSIIL 492



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.141    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,963
Number of extensions: 638
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)