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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              18    1135
NP_001243397                                                           18    1135
XP_005269721                                                           18    1135
NP_005856                                                              17    3301
NP_443100                                                              16    5631
NP_003175                                                              16    5631
NP_001193594                                                           16    5631
XP_006716684                                                           16    5631
XP_006711694                                                           16    5631
XP_005245671                                                           16    5631
NP_001006658                                                           16    7355
NP_065830                                                              16    7355
NP_001156787                                                           16    7355
XP_005272107                                                           16    7355
XP_005272105                                                           16    7355
NP_663160                                                              15    9605
NP_663162                                                              15    9605
NP_056365                                                              15    9605
NP_663161                                                              15    9605
NP_002509                                                              15    9605
XP_006715747                                                           15    9605
XP_006715746                                                           15    9605
XP_006715745                                                           15    9605
XP_006715744                                                           15    9605
XP_005249755                                                           15    9605
XP_005264018                                                           15    9605
XP_005264017                                                           15    9605
XP_005264016                                                           15    9605
XP_005264015                                                           15    9605
XP_005264014                                                           15    9605
XP_005264012                                                           15    9605
XP_005264011                                                           15    9605
XP_005264010                                                           15    9605

>NP_036462
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SSRLAVTD 9
           SSRLAVTD
Sbjct: 396 SSRLAVTD 403



>NP_001243397
          Length = 1890

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SSRLAVTD 9
           SSRLAVTD
Sbjct: 396 SSRLAVTD 403



>XP_005269721
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SSRLAVTD 9
           SSRLAVTD
Sbjct: 396 SSRLAVTD 403



>NP_005856
          Length = 514

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSSRLAVTD 9
           LSSRLA+ D
Sbjct: 151 LSSRLALAD 159



>NP_443100
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LSSRLAVT 8
           LSS+LAVT
Sbjct: 301 LSSQLAVT 308



>NP_003175
          Length = 1199

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SSRLAVTD 9
           +SRLA+TD
Sbjct: 676 ASRLALTD 683



>NP_001193594
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LSSRLAVT 8
           LSS+LAVT
Sbjct: 301 LSSQLAVT 308



>XP_006716684
          Length = 1251

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SSRLAVTD 9
           +SRLA+TD
Sbjct: 676 ASRLALTD 683



>XP_006711694
          Length = 596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LSSRLAVT 8
           LSS+LAVT
Sbjct: 284 LSSQLAVT 291



>XP_005245671
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LSSRLAVT 8
           LSS+LAVT
Sbjct: 301 LSSQLAVT 308



>NP_001006658
          Length = 1181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSRLAVTD 9
           SSRLA+ D
Sbjct: 555 SSRLAIID 562



>NP_065830
          Length = 1170

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSRLAVTD 9
           SSRLA+ D
Sbjct: 544 SSRLAIID 551



>NP_001156787
          Length = 701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSSR  VTD
Sbjct: 367 LSSRQQVTD 375



>XP_005272107
          Length = 505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSSR  VTD
Sbjct: 367 LSSRQQVTD 375



>XP_005272105
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSSR  VTD
Sbjct: 367 LSSRQQVTD 375



>NP_663160
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLAVTD 9
           SRL++TD
Sbjct: 409 SRLSITD 415



>NP_663162
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLAVTD 9
           SRL++TD
Sbjct: 373 SRLSITD 379



>NP_056365
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLAVTD 9
           SRL++TD
Sbjct: 440 SRLSITD 446



>NP_663161
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLAVTD 9
           SRL++TD
Sbjct: 404 SRLSITD 410



>NP_002509
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSS + VTD
Sbjct: 145 LSSHMLVTD 153



>XP_006715747
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  SRLAVTD 9
          SRL++TD
Sbjct: 87 SRLSITD 93



>XP_006715746
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLAVTD 9
           SRL++TD
Sbjct: 373 SRLSITD 379



>XP_006715745
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLAVTD 9
           SRL++TD
Sbjct: 404 SRLSITD 410



>XP_006715744
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLAVTD 9
           SRL++TD
Sbjct: 409 SRLSITD 415



>XP_005249755
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRLAVTD 9
           SRL++TD
Sbjct: 440 SRLSITD 446



>XP_005264018
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSSRLAVTD 9
          LSS + VTD
Sbjct: 21 LSSHMLVTD 29



>XP_005264017
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSS + VTD
Sbjct: 210 LSSHMLVTD 218



>XP_005264016
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSS + VTD
Sbjct: 210 LSSHMLVTD 218



>XP_005264015
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSS + VTD
Sbjct: 159 LSSHMLVTD 167



>XP_005264014
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSS + VTD
Sbjct: 210 LSSHMLVTD 218



>XP_005264012
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSS + VTD
Sbjct: 175 LSSHMLVTD 183



>XP_005264011
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSS + VTD
Sbjct: 210 LSSHMLVTD 218



>XP_005264010
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSSRLAVTD 9
           LSS + VTD
Sbjct: 210 LSSHMLVTD 218



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.122    0.286 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 232,903
Number of extensions: 220
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)