Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_003033                                                              17    3301
XP_006713369                                                           17    3301
XP_005265468                                                           17    3301
XP_005265467                                                           17    3301
NP_001121599                                                           16    7355
NP_001191948                                                           16    7355
NP_149991                                                              16    7355
XP_005274545                                                           16    7355
XP_006724549                                                           16    7355
XP_006724548                                                           16    7355
XP_006724546                                                           16    7355
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSMVMISG 9
            LSSM MISG
Sbjct: 1638 LSSMAMISG 1646
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSMVMISG 9
            LSSM MISG
Sbjct: 1689 LSSMAMISG 1697
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSMVMISG 9
            LSSM MISG
Sbjct: 1758 LSSMAMISG 1766
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSMVMISG 9
            LSSM MISG
Sbjct: 1707 LSSMAMISG 1715
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSMVMISG 9
            LSSM MISG
Sbjct: 1699 LSSMAMISG 1707
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSMVMISG 9
            LSSM MISG
Sbjct: 1700 LSSMAMISG 1708
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSMVMISG 9
            LSSM MISG
Sbjct: 1768 LSSMAMISG 1776
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSSMVMISG 9
            LSSM MISG
Sbjct: 1768 LSSMAMISG 1776
>NP_003033
          Length = 599

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           LSSMV+I G
Sbjct: 542 LSSMVLIPG 550
>XP_006713369
          Length = 599

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           LSSMV+I G
Sbjct: 542 LSSMVLIPG 550
>XP_005265468
          Length = 599

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           LSSMV+I G
Sbjct: 542 LSSMVLIPG 550
>XP_005265467
          Length = 599

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           LSSMV+I G
Sbjct: 542 LSSMVLIPG 550
>NP_001121599
          Length = 553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           +SSMVM+ G
Sbjct: 537 VSSMVMLIG 545
>NP_001191948
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           +SSMVM+ G
Sbjct: 543 VSSMVMLIG 551
>NP_149991
          Length = 553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           +SSMVM+ G
Sbjct: 537 VSSMVMLIG 545
>XP_005274545
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           +SSMVM+ G
Sbjct: 332 VSSMVMLIG 340
>XP_006724549
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           +SSMVM+ G
Sbjct: 338 VSSMVMLIG 346
>XP_006724548
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           +SSMVM+ G
Sbjct: 338 VSSMVMLIG 346
>XP_006724546
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMVMISG 9
           +SSMVM+ G
Sbjct: 565 VSSMVMLIG 573
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.126    0.295 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 170,931
Number of extensions: 98
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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