Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_000236                                                              16    7355
NP_001120972                                                           16    7355
XP_006716052                                                           16    7355
XP_006716051                                                           16    7355
NP_001254726                                                           15    9605
NP_055630                                                              15    9605
XP_005257931                                                           15    9605
XP_005257930                                                           15    9605
XP_005257929                                                           15    9605
XP_006722270                                                           15    9605
XP_006722269                                                           15    9605
XP_005257928                                                           15    9605
XP_006722268                                                           15    9605
XP_005257927                                                           15    9605
XP_006722267                                                           15    9605
XP_006722266                                                           15    9605
NP_001072986                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LSSMKDRA 8
            LSSMKDRA
Sbjct: 3140 LSSMKDRA 3147
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LSSMKDRA 8
            LSSMKDRA
Sbjct: 3132 LSSMKDRA 3139
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LSSMKDRA 8
            LSSMKDRA
Sbjct: 3093 LSSMKDRA 3100
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LSSMKDRA 8
            LSSMKDRA
Sbjct: 3172 LSSMKDRA 3179
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    LSSMKDRA 8
            LSSMKDRA
Sbjct: 3185 LSSMKDRA 3192
>NP_000236
          Length = 1390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LSSMKDR 7
           LSS+KDR
Sbjct: 185 LSSVKDR 191
>NP_001120972
          Length = 1408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LSSMKDR 7
           LSS+KDR
Sbjct: 185 LSSVKDR 191
>XP_006716052
          Length = 1409

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LSSMKDR 7
           LSS+KDR
Sbjct: 204 LSSVKDR 210
>XP_006716051
          Length = 1427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LSSMKDR 7
           LSS+KDR
Sbjct: 204 LSSVKDR 210
>NP_001254726
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 156 LSSTKNRAL 164
>NP_055630
          Length = 989

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 169 LSSTKNRAL 177
>XP_005257931
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 194 LSSTKNRAL 202
>XP_005257930
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 194 LSSTKNRAL 202
>XP_005257929
          Length = 1033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 194 LSSTKNRAL 202
>XP_006722270
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 169 LSSTKNRAL 177
>XP_006722269
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 169 LSSTKNRAL 177
>XP_005257928
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 169 LSSTKNRAL 177
>XP_006722268
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 169 LSSTKNRAL 177
>XP_005257927
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 194 LSSTKNRAL 202
>XP_006722267
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 194 LSSTKNRAL 202
>XP_006722266
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 194 LSSTKNRAL 202
>NP_001072986
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSMKDRAM 9
           LSS K+RA+
Sbjct: 156 LSSTKNRAL 164
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.117    0.276 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 350,313
Number of extensions: 273
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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