Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001093260                                                           17    4312
NP_001094101                                                           17    4312
NP_038477                                                              17    4312
XP_006719271                                                           17    4312
XP_005268661                                                           17    4312
XP_005268660                                                           17    4312
XP_005268659                                                           17    4312
XP_005268657                                                           17    4312
XP_006719270                                                           17    4312
XP_005268656                                                           17    4312
XP_005268654                                                           17    4312
XP_005268653                                                           17    4312
NP_001185797                                                           16    5631
NP_005177                                                              16    5631
NP_001185798                                                           16    5631
NP_055889                                                              16    5631
NP_055496                                                              16    5631
NP_001133                                                              16    5631
NP_001134                                                              16    5631
XP_005259500                                                           16    5631
XP_006718761                                                           16    5631
NP_036466                                                              16    7355
NP_689997                                                              16    7355
NP_001275728                                                           16    7355
NP_001087236                                                           16    7355
NP_065171                                                              16    7355
NP_997251                                                              16    7355
NP_065202                                                              16    7355
NP_940913                                                              16    7355
NP_001163802                                                           16    7355
NP_001275727                                                           16    7355
NP_997069                                                              16    7355
XP_006725017                                                           16    7355
XP_006714538                                                           16    7355
XP_006711144                                                           16    7355
NP_001941                                                              16    7355
NP_001136047                                                           15    9605
NP_001136046                                                           15    9605
NP_001136045                                                           15    9605
NP_001096075                                                           15    9605
NP_001136048                                                           15    9605
NP_899066                                                              15    9605
NP_000874                                                              15    9605
NP_001162593                                                           15    9605
NP_002016                                                              15    9605
NP_001162594                                                           15    9605
NP_001162595                                                           15    9605
NP_001162596                                                           15    9605
NP_001532                                                              15    9605
NP_001164099                                                           15    9605
NP_060117                                                              15    9605
XP_006726511                                                           15    9605
XP_006717822                                                           15    9605
XP_006717821                                                           15    9605
XP_005269749                                                           15    9605
XP_006717820                                                           15    9605
XP_006716291                                                           15    9605
XP_005250371                                                           15    9605
XP_005250370                                                           15    9605
XP_006716034                                                           15    9605
XP_006716033                                                           15    9605
XP_006716032                                                           15    9605
XP_006716031                                                           15    9605
XP_006716030                                                           15    9605
XP_006710245                                                           15    9605
NP_001025031                                                           15    9605
NP_065081                                                              15    9605
>NP_001093260
          Length = 479

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SEILTPL 9
           SE+LTPL
Sbjct: 427 SELLTPL 433
>NP_001094101
          Length = 481

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SEILTPL 9
           SE+LTPL
Sbjct: 429 SELLTPL 435
>NP_038477
          Length = 1905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1283 LSSSVLTP 1290
>XP_006719271
          Length = 1555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1302 LSSSVLTP 1309
>XP_005268661
          Length = 1657

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1035 LSSSVLTP 1042
>XP_005268660
          Length = 1875

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1253 LSSSVLTP 1260
>XP_005268659
          Length = 1894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1272 LSSSVLTP 1279
>XP_005268657
          Length = 1903

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1281 LSSSVLTP 1288
>XP_006719270
          Length = 1903

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1281 LSSSVLTP 1288
>XP_005268656
          Length = 1903

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1281 LSSSVLTP 1288
>XP_005268654
          Length = 1923

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1302 LSSSVLTP 1309
>XP_005268653
          Length = 1924

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSSEILTP 8
            LSS +LTP
Sbjct: 1302 LSSSVLTP 1309
>NP_001185797
          Length = 714

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 LSSEILTPL 9
         +S EI+TP+
Sbjct: 1 MSEEIITPV 9
>NP_005177
          Length = 714

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 LSSEILTPL 9
         +S EI+TP+
Sbjct: 1 MSEEIITPV 9
>NP_001185798
          Length = 714

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 LSSEILTPL 9
         +S EI+TP+
Sbjct: 1 MSEEIITPV 9
>NP_055889
          Length = 1770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SSEILTP 8
            SSE++TP
Sbjct: 1024 SSEVITP 1030
>NP_055496
          Length = 1143

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSEILTPL 9
           SSE LTP+
Sbjct: 569 SSEALTPI 576
>NP_001133
          Length = 191

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSEILTPL 9
          S E+LTPL
Sbjct: 32 SYEVLTPL 39
>NP_001134
          Length = 192

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSEILTPL 9
          S E+LTPL
Sbjct: 32 SYEVLTPL 39
>XP_005259500
          Length = 1143

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSEILTPL 9
           SSE LTP+
Sbjct: 569 SSEALTPI 576
>XP_006718761
          Length = 714

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1 LSSEILTPL 9
         +S EI+TP+
Sbjct: 1 MSEEIITPV 9
>NP_036466
          Length = 2058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           EILTPL
Sbjct: 384 EILTPL 389
>NP_689997
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           EILTPL
Sbjct: 351 EILTPL 356
>NP_001275728
          Length = 63

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SSEILTP 8
          SSEI TP
Sbjct: 25 SSEIFTP 31
>NP_001087236
          Length = 97

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SSEILTP 8
          SSEI TP
Sbjct: 25 SSEIFTP 31
>NP_065171
          Length = 238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSEILTPL 9
           + E+LTPL
Sbjct: 183 TQEVLTPL 190
>NP_997251
          Length = 97

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SSEILTP 8
          SSEI TP
Sbjct: 25 SSEIFTP 31
>NP_065202
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           EILTPL
Sbjct: 223 EILTPL 228
>NP_940913
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L+ E+LTP
Sbjct: 188 LAQEVLTP 195
>NP_001163802
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L+ E+LTP
Sbjct: 188 LAQEVLTP 195
>NP_001275727
          Length = 118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  SSEILTP 8
          SSEI TP
Sbjct: 46 SSEIFTP 52
>NP_997069
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           LSS ++TP+
Sbjct: 277 LSSTVVTPM 285
>XP_006725017
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           EILTPL
Sbjct: 183 EILTPL 188
>XP_006714538
          Length = 2035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           EILTPL
Sbjct: 384 EILTPL 389
>XP_006711144
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           EILTPL
Sbjct: 183 EILTPL 188
>NP_001941
          Length = 413

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSSEILTPL 9
           +SSE+  PL
Sbjct: 372 MSSEVFAPL 380
>NP_001136047
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 149 LLSEVMTP 156
>NP_001136046
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 169 LLSEVMTP 176
>NP_001136045
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 174 LLSEVMTP 181
>NP_001096075
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 249 LLSEVMTP 256
>NP_001136048
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 226 LLSEVMTP 233
>NP_899066
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 223 LLSEVMTP 230
>NP_000874
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 259 LLSEVMTP 266
>NP_001162593
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           + +EIL+PL
Sbjct: 751 MQTEILSPL 759
>NP_002016
          Length = 1311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           + +EIL+PL
Sbjct: 784 MQTEILSPL 792
>NP_001162594
          Length = 1301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           + +EIL+PL
Sbjct: 774 MQTEILSPL 782
>NP_001162595
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           + +EIL+PL
Sbjct: 749 MQTEILSPL 757
>NP_001162596
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           + +EIL+PL
Sbjct: 745 MQTEILSPL 753
>NP_001532
          Length = 182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  LSSEILTP 8
          L  EILTP
Sbjct: 34 LPEEILTP 41
>NP_001164099
          Length = 952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           + +EIL+PL
Sbjct: 425 MQTEILSPL 433
>NP_060117
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           L +EI++PL
Sbjct: 578 LKTEIMSPL 586
>XP_006726511
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           LSSE+L+ L
Sbjct: 261 LSSEVLSSL 269
>XP_006717822
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           E+LTPL
Sbjct: 431 EVLTPL 436
>XP_006717821
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           E+LTPL
Sbjct: 431 EVLTPL 436
>XP_005269749
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           E+LTPL
Sbjct: 431 EVLTPL 436
>XP_006717820
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           E+LTPL
Sbjct: 431 EVLTPL 436
>XP_006716291
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           LSSE+L+ L
Sbjct: 261 LSSEVLSSL 269
>XP_005250371
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 182 LLSEVMTP 189
>XP_005250370
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 190 LLSEVMTP 197
>XP_006716034
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 182 LLSEVMTP 189
>XP_006716033
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 190 LLSEVMTP 197
>XP_006716032
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 223 LLSEVMTP 230
>XP_006716031
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 249 LLSEVMTP 256
>XP_006716030
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSSEILTP 8
           L SE++TP
Sbjct: 259 LLSEVMTP 266
>XP_006710245
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSSEILTPL 9
           LSSE+L+ L
Sbjct: 261 LSSEVLSSL 269
>NP_001025031
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           E+LTPL
Sbjct: 604 EVLTPL 609
>NP_065081
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EILTPL 9
           E+LTPL
Sbjct: 431 EVLTPL 436
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.131    0.326 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 527,902
Number of extensions: 893
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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