Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     869
XP_006718908                                                           19     869
XP_005271621                                                           19     869
XP_006718907                                                           19     869
XP_006718906                                                           19     869
XP_005271619                                                           19     869
XP_005271618                                                           19     869
XP_006726635                                                           17    3301
XP_006726634                                                           17    3301
XP_006726632                                                           17    3301
XP_003846802                                                           17    3301
NP_001321                                                              16    7355
NP_859066                                                              16    7355
NP_653267                                                              16    7355
NP_055059                                                              16    7355
NP_001258765                                                           16    7355
NP_001156795                                                           16    7355
NP_060487                                                              16    7355
NP_296375                                                              16    7355
NP_001156794                                                           16    7355
NP_001156793                                                           16    7355
NP_001258764                                                           16    7355
NP_067610                                                              16    7355
XP_005269994                                                           16    7355
XP_005245006                                                           16    7355
XP_006711262                                                           16    7355
XP_005245003                                                           16    7355
NP_060502                                                              15    9605
NP_958815                                                              15    9605
NP_001092007                                                           15    9605
NP_689499                                                              15    9605
NP_060783                                                              15    9605
NP_001424                                                              15    9605
NP_055273                                                              15    9605
NP_005236                                                              15    9605
XP_005258156                                                           15    9605
XP_005258155                                                           15    9605
XP_006721832                                                           15    9605
XP_006720967                                                           15    9605
XP_005255486                                                           15    9605
XP_005255485                                                           15    9605
XP_005255484                                                           15    9605
XP_006720966                                                           15    9605
XP_005255483                                                           15    9605
XP_006717167                                                           15    9605
XP_006717166                                                           15    9605
XP_006717165                                                           15    9605
XP_006714202                                                           15    9605
XP_005262892                                                           15    9605
XP_005262891                                                           15    9605
XP_006713297                                                           15    9605
XP_006713296                                                           15    9605
XP_006713295                                                           15    9605
XP_005265345                                                           15    9605
XP_006713294                                                           15    9605
XP_006713293                                                           15    9605
XP_006713292                                                           15    9605
XP_006713291                                                           15    9605
XP_006713290                                                           15    9605
XP_006713289                                                           15    9605
XP_005265340                                                           15    9605
XP_005265339                                                           15    9605
XP_006713288                                                           15    9605
XP_005265337                                                           15    9605
XP_005265336                                                           15    9605
XP_006713287                                                           15    9605
XP_006713286                                                           15    9605
XP_005265332                                                           15    9605
XP_006713285                                                           15    9605
XP_006713284                                                           15    9605
XP_006713283                                                           15    9605
XP_005245150                                                           15    9605
XP_006711340                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRRSGVLE 9
            LS+RSGVLE
Sbjct: 2760 LSQRSGVLE 2768
>XP_006718908
          Length = 1708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRRSGVLE 9
            LS+RSGVLE
Sbjct: 1412 LSQRSGVLE 1420
>XP_005271621
          Length = 2708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRRSGVLE 9
            LS+RSGVLE
Sbjct: 2412 LSQRSGVLE 2420
>XP_006718907
          Length = 3050

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRRSGVLE 9
            LS+RSGVLE
Sbjct: 2754 LSQRSGVLE 2762
>XP_006718906
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRRSGVLE 9
            LS+RSGVLE
Sbjct: 2760 LSQRSGVLE 2768
>XP_005271619
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRRSGVLE 9
            LS+RSGVLE
Sbjct: 2760 LSQRSGVLE 2768
>XP_005271618
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRRSGVLE 9
            LS+RSGVLE
Sbjct: 2760 LSQRSGVLE 2768
>XP_006726635
          Length = 284

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSRRSGV
Sbjct: 179 LSRRSGV 185
>XP_006726634
          Length = 284

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSRRSGV
Sbjct: 179 LSRRSGV 185
>XP_006726632
          Length = 335

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSRRSGV
Sbjct: 179 LSRRSGV 185
>XP_003846802
          Length = 205

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSRRSGV
Sbjct: 179 LSRRSGV 185
>NP_001321
          Length = 201

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1 LSRRSGVLE 9
         +SRR G LE
Sbjct: 1 MSRREGSLE 9
>NP_859066
          Length = 693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SRRSGVLE 9
           SRR G+L+
Sbjct: 199 SRRGGILD 206
>NP_653267
          Length = 4753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSRRSGVL 8
            LSR SG+L
Sbjct: 1982 LSRASGIL 1989
>NP_055059
          Length = 1211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSRRSGVLE 9
           LSR  GVLE
Sbjct: 239 LSRALGVLE 247
>NP_001258765
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSRRSGVL 8
           LSRR G+L
Sbjct: 475 LSRRDGLL 482
>NP_001156795
          Length = 618

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSRRSGVL 8
           LSRR G+L
Sbjct: 463 LSRRDGLL 470
>NP_060487
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSRRSGVL 8
           LSRR G++
Sbjct: 824 LSRRGGIM 831
>NP_296375
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSRRSGVL 8
           LSRR G+L
Sbjct: 475 LSRRDGLL 482
>NP_001156794
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSRRSGVL 8
           LSRR G+L
Sbjct: 463 LSRRDGLL 470
>NP_001156793
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSRRSGVL 8
           LSRR G+L
Sbjct: 510 LSRRDGLL 517
>NP_001258764
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LSRRSGVL 8
           LSRR G+L
Sbjct: 475 LSRRDGLL 482
>NP_067610
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSRRSGVLE 9
           LSR  GVLE
Sbjct: 239 LSRALGVLE 247
>XP_005269994
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LSRRSGVL 8
           LSRR G++
Sbjct: 824 LSRRGGIM 831
>XP_005245006
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SRRSGVLE 9
          SRR G+L+
Sbjct: 86 SRRGGILD 93
>XP_006711262
          Length = 689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SRRSGVLE 9
           SRR G+L+
Sbjct: 190 SRRGGILD 197
>XP_005245003
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SRRSGVLE 9
           SRR G+L+
Sbjct: 199 SRRGGILD 206
>NP_060502
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 256 LSRRSG 261
>NP_958815
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 256 LSRRSG 261
>NP_001092007
          Length = 1342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    RSGVLE 9
            RSGVLE
Sbjct: 1231 RSGVLE 1236
>NP_689499
          Length = 1317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    RSGVLE 9
            RSGVLE
Sbjct: 1206 RSGVLE 1211
>NP_060783
          Length = 1582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 641 LSRKSGI 647
>NP_001424
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SRRSGV 7
           SRRSGV
Sbjct: 726 SRRSGV 731
>NP_055273
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SRRSGV 7
           SRRSGV
Sbjct: 542 SRRSGV 547
>NP_005236
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSRRSGVL 8
            +SR SGVL
Sbjct: 2025 ISRTSGVL 2032
>XP_005258156
          Length = 1905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 97  LSRRSG 102
>XP_005258155
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 97  LSRRSG 102
>XP_006721832
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SRRSGV 7
           SRRSGV
Sbjct: 841 SRRSGV 846
>XP_006720967
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 203 LSRRSG 208
>XP_005255486
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 170 LSRRSG 175
>XP_005255485
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 170 LSRRSG 175
>XP_005255484
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 203 LSRRSG 208
>XP_006720966
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 203 LSRRSG 208
>XP_005255483
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LSRRSG 6
           LSRRSG
Sbjct: 256 LSRRSG 261
>XP_006717167
          Length = 1309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    RSGVLE 9
            RSGVLE
Sbjct: 1198 RSGVLE 1203
>XP_006717166
          Length = 1316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    RSGVLE 9
            RSGVLE
Sbjct: 1205 RSGVLE 1210
>XP_006717165
          Length = 1343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    RSGVLE 9
            RSGVLE
Sbjct: 1232 RSGVLE 1237
>XP_006714202
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSRRSGVL 8
            +SR SGVL
Sbjct: 2025 ISRTSGVL 2032
>XP_005262892
          Length = 4600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSRRSGVL 8
            +SR SGVL
Sbjct: 2025 ISRTSGVL 2032
>XP_005262891
          Length = 4600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSRRSGVL 8
            +SR SGVL
Sbjct: 2025 ISRTSGVL 2032
>XP_006713297
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 659 LSRKSGI 665
>XP_006713296
          Length = 1615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 674 LSRKSGI 680
>XP_006713295
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 627 LSRKSGI 633
>XP_005265345
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 659 LSRKSGI 665
>XP_006713294
          Length = 1652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 659 LSRKSGI 665
>XP_006713293
          Length = 1667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 674 LSRKSGI 680
>XP_006713292
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 674 LSRKSGI 680
>XP_006713291
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 659 LSRKSGI 665
>XP_006713290
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 642 LSRKSGI 648
>XP_006713289
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 674 LSRKSGI 680
>XP_005265340
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 656 LSRKSGI 662
>XP_005265339
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 656 LSRKSGI 662
>XP_006713288
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 656 LSRKSGI 662
>XP_005265337
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 656 LSRKSGI 662
>XP_005265336
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 656 LSRKSGI 662
>XP_006713287
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 656 LSRKSGI 662
>XP_006713286
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 659 LSRKSGI 665
>XP_005265332
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 674 LSRKSGI 680
>XP_006713285
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 674 LSRKSGI 680
>XP_006713284
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 674 LSRKSGI 680
>XP_006713283
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LSRRSGV 7
           LSR+SG+
Sbjct: 674 LSRKSGI 680
>XP_005245150
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SRRSGV 7
           SRRSGV
Sbjct: 542 SRRSGV 547
>XP_006711340
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SRRSGV 7
           SRRSGV
Sbjct: 617 SRRSGV 622
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.134    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 498,154
Number of extensions: 674
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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