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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              20     509
NP_671714                                                              20     509
XP_006715890                                                           20     509
XP_005250160                                                           20     509
XP_005250159                                                           20     509
NP_001275997                                                           17    4312
NP_060533                                                              17    4312
NP_001276001                                                           17    4312
NP_001275999                                                           17    4312
NP_001275998                                                           17    4312
NP_001275996                                                           17    4312
XP_006717874                                                           17    4312
NP_005344                                                              16    5631
XP_006716441                                                           16    5631
NP_001017415                                                           16    5631
NP_003359                                                              16    5631
NP_001017416                                                           16    5631
XP_005266168                                                           16    7355
NP_055453                                                              15    9605
NP_065842                                                              15    9605
NP_777612                                                              15    9605
XP_006725014                                                           15    9605
XP_006725013                                                           15    9605
XP_006725012                                                           15    9605
XP_006714249                                                           15    9605
XP_006711118                                                           15    9605
XP_006711117                                                           15    9605

>NP_005742
          Length = 3907

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRQKESMK 9
            LSRQKE+MK
Sbjct: 1976 LSRQKEAMK 1984



>NP_671714
          Length = 3899

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRQKESMK 9
            LSRQKE+MK
Sbjct: 1976 LSRQKEAMK 1984



>XP_006715890
          Length = 3860

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRQKESMK 9
            LSRQKE+MK
Sbjct: 1929 LSRQKEAMK 1937



>XP_005250160
          Length = 3939

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRQKESMK 9
            LSRQKE+MK
Sbjct: 2008 LSRQKEAMK 2016



>XP_005250159
          Length = 3952

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSRQKESMK 9
            LSRQKE+MK
Sbjct: 2008 LSRQKEAMK 2016



>NP_001275997
          Length = 822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LSRQKESMK 9
          L R+KES+K
Sbjct: 84 LERKKESLK 92



>NP_060533
          Length = 838

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSRQKESMK 9
           L R+KES+K
Sbjct: 100 LERKKESLK 108



>NP_001276001
          Length = 708

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSRQKESMK 9
           L R+KES+K
Sbjct: 100 LERKKESLK 108



>NP_001275999
          Length = 740

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSRQKESMK 9
           L R+KES+K
Sbjct: 100 LERKKESLK 108



>NP_001275998
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSRQKESMK 9
           L R+KES+K
Sbjct: 100 LERKKESLK 108



>NP_001275996
          Length = 884

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSRQKESMK 9
           L R+KES+K
Sbjct: 100 LERKKESLK 108



>XP_006717874
          Length = 813

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSRQKESMK 9
           L R+KES+K
Sbjct: 100 LERKKESLK 108



>NP_005344
          Length = 1161

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSRQKESMK 9
           +SRQ+ES K
Sbjct: 925 ISRQEESTK 933



>XP_006716441
          Length = 427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RQKESMK 9
           R+KESMK
Sbjct: 171 RKKESMK 177



>NP_001017415
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LSRQKESMK 9
           +SR+KE++K
Sbjct: 116 ISRKKEALK 124



>NP_003359
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LSRQKESMK 9
           +SR+KE++K
Sbjct: 116 ISRKKEALK 124



>NP_001017416
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LSRQKESMK 9
           +SR+KE++K
Sbjct: 116 ISRKKEALK 124



>XP_005266168
          Length = 927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSRQKESMK 9
           LSRQKE  +
Sbjct: 914 LSRQKEEKR 922



>NP_055453
          Length = 1416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQKESMK 9
           +RQK++MK
Sbjct: 614 TRQKKTMK 621



>NP_065842
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LSRQKESMK 9
           LS+QKE+++
Sbjct: 585 LSKQKENIQ 593



>NP_777612
          Length = 459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSRQKESMK 9
           LSR K +MK
Sbjct: 336 LSRAKRTMK 344



>XP_006725014
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQKESMK 9
           +RQK++MK
Sbjct: 587 TRQKKTMK 594



>XP_006725013
          Length = 1389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQKESMK 9
           +RQK++MK
Sbjct: 587 TRQKKTMK 594



>XP_006725012
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQKESMK 9
           +RQK++MK
Sbjct: 586 TRQKKTMK 593



>XP_006714249
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSRQKESMK 9
           LSR K +MK
Sbjct: 128 LSRAKRTMK 136



>XP_006711118
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQKESMK 9
           +RQK++MK
Sbjct: 587 TRQKKTMK 594



>XP_006711117
          Length = 1413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRQKESMK 9
           +RQK++MK
Sbjct: 611 TRQKKTMK 618



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.108    0.239 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 492,172
Number of extensions: 553
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)