Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1482
NP_671714                                                              18    1482
XP_006715890                                                           18    1482
XP_005250160                                                           18    1482
XP_005250159                                                           18    1482
NP_036367                                                              18    1935
XP_005265029                                                           18    1935
XP_005265028                                                           18    1935
XP_005265027                                                           18    1935
XP_005265026                                                           18    1935
XP_005265025                                                           18    1935
XP_005265024                                                           18    1935
XP_006713097                                                           18    1935
NP_001230175                                                           16    5631
NP_071751                                                              16    5631
NP_001139761                                                           16    5631
XP_005271167                                                           16    5631
NP_075563                                                              15    9605
NP_001229833                                                           15    9605
XP_006722410                                                           15    9605
XP_006722409                                                           15    9605
XP_006722408                                                           15    9605
XP_006722407                                                           15    9605
XP_006722406                                                           15    9605
XP_006722405                                                           15    9605
XP_006722404                                                           15    9605
XP_006722403                                                           15    9605
NP_659490                                                              15    9605
NP_060954                                                              15    9605
>NP_005742
          Length = 3907

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSQRLVMSG 9
            LSQRLV SG
Sbjct: 1821 LSQRLVRSG 1829
>NP_671714
          Length = 3899

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSQRLVMSG 9
            LSQRLV SG
Sbjct: 1821 LSQRLVRSG 1829
>XP_006715890
          Length = 3860

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSQRLVMSG 9
            LSQRLV SG
Sbjct: 1774 LSQRLVRSG 1782
>XP_005250160
          Length = 3939

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSQRLVMSG 9
            LSQRLV SG
Sbjct: 1853 LSQRLVRSG 1861
>XP_005250159
          Length = 3952

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSQRLVMSG 9
            LSQRLV SG
Sbjct: 1853 LSQRLVRSG 1861
>NP_036367
          Length = 1279

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSQRLVMSG 9
           L+QRL+M+G
Sbjct: 515 LAQRLIMAG 523
>XP_005265029
          Length = 886

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSQRLVMSG 9
           L+QRL+M+G
Sbjct: 123 LAQRLIMAG 131
>XP_005265028
          Length = 887

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSQRLVMSG 9
           L+QRL+M+G
Sbjct: 123 LAQRLIMAG 131
>XP_005265027
          Length = 887

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSQRLVMSG 9
           L+QRL+M+G
Sbjct: 123 LAQRLIMAG 131
>XP_005265026
          Length = 1023

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSQRLVMSG 9
           L+QRL+M+G
Sbjct: 260 LAQRLIMAG 268
>XP_005265025
          Length = 1024

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSQRLVMSG 9
           L+QRL+M+G
Sbjct: 260 LAQRLIMAG 268
>XP_005265024
          Length = 1278

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSQRLVMSG 9
           L+QRL+M+G
Sbjct: 515 LAQRLIMAG 523
>XP_006713097
          Length = 1279

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSQRLVMSG 9
           L+QRL+M+G
Sbjct: 515 LAQRLIMAG 523
>NP_001230175
          Length = 804

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SQRLVMSG 9
           SQR+VM G
Sbjct: 469 SQRVVMDG 476
>NP_071751
          Length = 736

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SQRLVMSG 9
           SQR+VM G
Sbjct: 469 SQRVVMDG 476
>NP_001139761
          Length = 697

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SQRLVMSG 9
           SQR+VM G
Sbjct: 469 SQRVVMDG 476
>XP_005271167
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SQRLVMSG 9
           SQR+VM G
Sbjct: 133 SQRVVMDG 140
>NP_075563
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 294 LQPRLVLSG 302
>NP_001229833
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 231 LQPRLVLSG 239
>XP_006722410
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 272 LQPRLVLSG 280
>XP_006722409
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 294 LQPRLVLSG 302
>XP_006722408
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 295 LQPRLVLSG 303
>XP_006722407
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 295 LQPRLVLSG 303
>XP_006722406
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 295 LQPRLVLSG 303
>XP_006722405
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 295 LQPRLVLSG 303
>XP_006722404
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 295 LQPRLVLSG 303
>XP_006722403
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           L  RLV+SG
Sbjct: 295 LQPRLVLSG 303
>NP_659490
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  LSQRLVMSG 9
          LSQR +M G
Sbjct: 85 LSQRGIMDG 93
>NP_060954
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSQRLVMSG 9
           LSQ + MSG
Sbjct: 144 LSQSIFMSG 152
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.132    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 288,580
Number of extensions: 512
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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