Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1135
NP_001119584                                                           18    1135
NP_001119586                                                           18    1135
NP_001119585                                                           18    1135
NP_060890                                                              18    1935
XP_006710817                                                           18    1935
XP_005271062                                                           18    1935
XP_006710816                                                           18    1935
NP_055832                                                              17    3301
NP_203133                                                              17    3301
NP_963920                                                              17    3301
NP_963918                                                              17    3301
XP_005270706                                                           17    3301
XP_005270705                                                           17    3301
NP_439896                                                              17    4312
NP_006328                                                              17    4312
NP_001265270                                                           17    4312
XP_005268630                                                           17    4312
XP_005268629                                                           17    4312
XP_006715391                                                           17    4312
NP_001012300                                                           17    4312
NP_003743                                                              16    5631
NP_001254503                                                           16    5631
NP_001273407                                                           16    5631
NP_001032897                                                           16    5631
NP_001186071                                                           16    5631
NP_001093131                                                           16    5631
XP_005255592                                                           16    5631
NP_001099129                                                           16    7355
NP_115871                                                              16    7355
NP_001035543                                                           16    7355
NP_001035540                                                           16    7355
XP_006722986                                                           16    7355
XP_005259717                                                           16    7355
XP_005259716                                                           16    7355
XP_006710416                                                           16    7355
XP_006710415                                                           16    7355
XP_005270511                                                           16    7355
NP_001001711                                                           16    7355
NP_612459                                                              15    9605
NP_000724                                                              15    9605
NP_001158307                                                           15    9605
NP_061952                                                              15    9605
NP_001008563                                                           15    9605
NP_006667                                                              15    9605
NP_001103773                                                           15    9605
NP_056483                                                              15    9605
NP_001230141                                                           15    9605
NP_078988                                                              15    9605
NP_001273621                                                           15    9605
XP_006726450                                                           15    9605
XP_006723389                                                           15    9605
XP_005266310                                                           15    9605
XP_005251723                                                           15    9605
XP_006717001                                                           15    9605
XP_005251722                                                           15    9605
XP_006716779                                                           15    9605
XP_005250917                                                           15    9605
XP_006716604                                                           15    9605
XP_005250916                                                           15    9605
XP_005250915                                                           15    9605
XP_005250914                                                           15    9605
XP_005250913                                                           15    9605
XP_006712223                                                           15    9605
XP_006710190                                                           15    9605
>NP_000537
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LSLETFSDL 9
          LS ETFSDL
Sbjct: 14 LSQETFSDL 22
>NP_001119584
          Length = 393

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LSLETFSDL 9
          LS ETFSDL
Sbjct: 14 LSQETFSDL 22
>NP_001119586
          Length = 341

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LSLETFSDL 9
          LS ETFSDL
Sbjct: 14 LSQETFSDL 22
>NP_001119585
          Length = 346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LSLETFSDL 9
          LS ETFSDL
Sbjct: 14 LSQETFSDL 22
>NP_060890
          Length = 547

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LETFSDL 9
           LETFSDL
Sbjct: 490 LETFSDL 496
>XP_006710817
          Length = 315

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LETFSDL 9
           LETFSDL
Sbjct: 258 LETFSDL 264
>XP_005271062
          Length = 316

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LETFSDL 9
           LETFSDL
Sbjct: 259 LETFSDL 265
>XP_006710816
          Length = 476

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LETFSDL 9
           LETFSDL
Sbjct: 419 LETFSDL 425
>NP_055832
          Length = 942

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           ++LETF DL
Sbjct: 497 VTLETFQDL 505
>NP_203133
          Length = 307

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LSLETFSDL 9
           L++ETFS+L
Sbjct: 251 LAVETFSEL 259
>NP_963920
          Length = 828

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           ++LETF DL
Sbjct: 497 VTLETFQDL 505
>NP_963918
          Length = 911

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           ++LETF DL
Sbjct: 466 VTLETFQDL 474
>XP_005270706
          Length = 851

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           ++LETF DL
Sbjct: 497 VTLETFQDL 505
>XP_005270705
          Length = 934

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           ++LETF DL
Sbjct: 497 VTLETFQDL 505
>NP_439896
          Length = 456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           SLETFS L
Sbjct: 169 SLETFSGL 176
>NP_006328
          Length = 462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           +LETF DL
Sbjct: 227 TLETFQDL 234
>NP_001265270
          Length = 271

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SLETFSDL 9
          +LETF DL
Sbjct: 36 TLETFQDL 43
>XP_005268630
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           +LETF DL
Sbjct: 138 TLETFQDL 145
>XP_005268629
          Length = 462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           +LETF DL
Sbjct: 227 TLETFQDL 234
>XP_006715391
          Length = 431

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           SLETFS L
Sbjct: 169 SLETFSGL 176
>NP_001012300
          Length = 475

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           +LETF DL
Sbjct: 240 TLETFQDL 247
>NP_003743
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           +S+ET SD+
Sbjct: 802 ISMETLSDM 810
>NP_001254503
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           +S+ET SD+
Sbjct: 802 ISMETLSDM 810
>NP_001273407
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           +S+ET SD+
Sbjct: 792 ISMETLSDM 800
>NP_001032897
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           +S+ET SD+
Sbjct: 802 ISMETLSDM 810
>NP_001186071
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           +S+ET SD+
Sbjct: 802 ISMETLSDM 810
>NP_001093131
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           +S+ET SD+
Sbjct: 803 ISMETLSDM 811
>XP_005255592
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSLETFSDL 9
           +S+ET SD+
Sbjct: 803 ISMETLSDM 811
>NP_001099129
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSLETFSDL 9
           + L TFSD+
Sbjct: 415 MKLRTFSDI 423
>NP_115871
          Length = 1537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSLETFSD 8
            LSL +FSD
Sbjct: 1326 LSLHSFSD 1333
>NP_001035543
          Length = 620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SLETFSDL 9
           SLE+FS+L
Sbjct: 175 SLESFSNL 182
>NP_001035540
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SLETFSDL 9
           SLE+FS+L
Sbjct: 175 SLESFSNL 182
>XP_006722986
          Length = 1519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSLETFSD 8
            LSL +FSD
Sbjct: 1107 LSLHSFSD 1114
>XP_005259717
          Length = 1738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSLETFSD 8
            LSL +FSD
Sbjct: 1326 LSLHSFSD 1333
>XP_005259716
          Length = 1738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LSLETFSD 8
            LSL +FSD
Sbjct: 1326 LSLHSFSD 1333
>XP_006710416
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSLETFSDL 9
           + L TFSD+
Sbjct: 95  MKLRTFSDI 103
>XP_006710415
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSLETFSDL 9
           + L TFSD+
Sbjct: 95  MKLRTFSDI 103
>XP_005270511
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LSLETFSDL 9
           + L TFSD+
Sbjct: 95  MKLRTFSDI 103
>NP_001001711
          Length = 396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           SLETFS +
Sbjct: 175 SLETFSQV 182
>NP_612459
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LSLETFSD 8
           LSLE F D
Sbjct: 139 LSLERFQD 146
>NP_000724
          Length = 207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LSLETFSDL 9
          LSL+ FS+L
Sbjct: 82 LSLKEFSEL 90
>NP_001158307
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETFSDL 9
           ++TFSDL
Sbjct: 290 IKTFSDL 296
>NP_061952
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LETFSDL 9
           ++TFSDL
Sbjct: 290 IKTFSDL 296
>NP_001008563
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           ++ETF DL
Sbjct: 468 TVETFQDL 475
>NP_006667
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           ++ETF DL
Sbjct: 468 TVETFQDL 475
>NP_001103773
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           ++ETF DL
Sbjct: 468 TVETFQDL 475
>NP_056483
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSLETFSD 8
          LSL TFS+
Sbjct: 36 LSLPTFSE 43
>NP_001230141
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LETFSDL 9
           +ETF DL
Sbjct: 148 METFEDL 154
>NP_078988
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LSLETFSDL 9
           LSL  FS+L
Sbjct: 198 LSLRAFSEL 206
>NP_001273621
          Length = 1252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSLETFSD 8
          LSL TFS+
Sbjct: 36 LSLPTFSE 43
>XP_006726450
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSLETFSDL 9
           LSL TFS L
Sbjct: 448 LSLGTFSPL 456
>XP_006723389
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LETFSDL 9
           +ETF DL
Sbjct: 189 METFEDL 195
>XP_005266310
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LSLETFSD 8
           LSLE F D
Sbjct: 139 LSLERFQD 146
>XP_005251723
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           ++ETF DL
Sbjct: 229 TVETFQDL 236
>XP_006717001
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           ++ETF DL
Sbjct: 468 TVETFQDL 475
>XP_005251722
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SLETFSDL 9
           ++ETF DL
Sbjct: 468 TVETFQDL 475
>XP_006716779
          Length = 2399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ETFSDL 9
           ETFSD+
Sbjct: 960 ETFSDM 965
>XP_005250917
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSLETFSD 8
          LSL TFS+
Sbjct: 36 LSLPTFSE 43
>XP_006716604
          Length = 1045

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSLETFSD 8
          LSL TFS+
Sbjct: 36 LSLPTFSE 43
>XP_005250916
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSLETFSD 8
          LSL TFS+
Sbjct: 36 LSLPTFSE 43
>XP_005250915
          Length = 1210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSLETFSD 8
          LSL TFS+
Sbjct: 36 LSLPTFSE 43
>XP_005250914
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSLETFSD 8
          LSL TFS+
Sbjct: 36 LSLPTFSE 43
>XP_005250913
          Length = 1211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LSLETFSD 8
          LSL TFS+
Sbjct: 36 LSLPTFSE 43
>XP_006712223
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSLETFSDL 9
           LSL TFS L
Sbjct: 448 LSLGTFSPL 456
>XP_006710190
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LSLETFSDL 9
           LSL TFS L
Sbjct: 390 LSLGTFSPL 398
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.134    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,609
Number of extensions: 808
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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