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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     390
XP_006718908                                                           20     390
XP_005271621                                                           20     390
XP_006718907                                                           20     390
XP_006718906                                                           20     390
XP_005271619                                                           20     390
XP_005271618                                                           20     390
NP_001092286                                                           17    2528
XP_006718561                                                           17    2528
NP_003140                                                              17    4312
NP_001116151                                                           17    4312
XP_005266009                                                           17    4312
XP_006714961                                                           17    4312
XP_006714960                                                           17    4312
XP_005266007                                                           17    4312
XP_006713372                                                           17    4312
XP_006713371                                                           17    4312
NP_940980                                                              16    5631
XP_005268686                                                           16    5631
NP_114095                                                              16    7355
XP_006714119                                                           16    7355
XP_006710438                                                           16    7355
XP_006710437                                                           16    7355
XP_006710436                                                           16    7355
XP_006710430                                                           16    7355
NP_001721                                                              15    9605
NP_001273747                                                           15    9605
NP_001277137                                                           15    9605
NP_001277138                                                           15    9605
NP_001121695                                                           15    9605
NP_055918                                                              15    9605
XP_006719925                                                           15    9605
XP_005266566                                                           15    9605
XP_006712975                                                           15    9605
XP_006712974                                                           15    9605
XP_005264770                                                           15    9605
XP_005264768                                                           15    9605
XP_005264767                                                           15    9605
XP_006712973                                                           15    9605

>NP_000042
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSKMAIHHT 9
            LSKMAI+HT
Sbjct: 1654 LSKMAINHT 1662



>XP_006718908
          Length = 1708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   LSKMAIHHT 9
           LSKMAI+HT
Sbjct: 306 LSKMAINHT 314



>XP_005271621
          Length = 2708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSKMAIHHT 9
            LSKMAI+HT
Sbjct: 1306 LSKMAINHT 1314



>XP_006718907
          Length = 3050

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSKMAIHHT 9
            LSKMAI+HT
Sbjct: 1648 LSKMAINHT 1656



>XP_006718906
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSKMAIHHT 9
            LSKMAI+HT
Sbjct: 1654 LSKMAINHT 1662



>XP_005271619
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSKMAIHHT 9
            LSKMAI+HT
Sbjct: 1654 LSKMAINHT 1662



>XP_005271618
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LSKMAIHHT 9
            LSKMAI+HT
Sbjct: 1654 LSKMAINHT 1662



>NP_001092286
          Length = 2769

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LSKMAIHHT 9
            LSK+AIH T
Sbjct: 1458 LSKVAIHAT 1466



>XP_006718561
          Length = 2794

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LSKMAIHHT 9
            LSK+AIH T
Sbjct: 1483 LSKVAIHAT 1491



>NP_003140
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KMAIHH 8
           KM+IHH
Sbjct: 143 KMSIHH 148



>NP_001116151
          Length = 2765

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LSKMAIH 7
            LSK+AIH
Sbjct: 1456 LSKLAIH 1462



>XP_005266009
          Length = 2378

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LSKMAIH 7
            LSK+AIH
Sbjct: 1069 LSKLAIH 1075



>XP_006714961
          Length = 2548

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LSKMAIH 7
            LSK+AIH
Sbjct: 1239 LSKLAIH 1245



>XP_006714960
          Length = 2758

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LSKMAIH 7
            LSK+AIH
Sbjct: 1449 LSKLAIH 1455



>XP_005266007
          Length = 2765

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    LSKMAIH 7
            LSK+AIH
Sbjct: 1456 LSKLAIH 1462



>XP_006713372
          Length = 334

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  KMAIHH 8
          KM+IHH
Sbjct: 75 KMSIHH 80



>XP_006713371
          Length = 377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KMAIHH 8
           KM+IHH
Sbjct: 143 KMSIHH 148



>NP_940980
          Length = 2527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SKMAIHHT 9
           SK+ +HH+
Sbjct: 663 SKLLVHHS 670



>XP_005268686
          Length = 2521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SKMAIHHT 9
           SK+ +HH+
Sbjct: 663 SKLLVHHS 670



>NP_114095
          Length = 1142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKMAIHHT 9
            SK+A HH+
Sbjct: 1060 SKLAKHHS 1067



>XP_006714119
          Length = 1142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SKMAIHHT 9
            SK+A HH+
Sbjct: 1060 SKLAKHHS 1067



>XP_006710438
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SKMAIHHT 9
           +KM +HH+
Sbjct: 341 AKMLLHHS 348



>XP_006710437
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SKMAIHHT 9
           +KM +HH+
Sbjct: 341 AKMLLHHS 348



>XP_006710436
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SKMAIHHT 9
           +KM +HH+
Sbjct: 355 AKMLLHHS 362



>XP_006710430
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SKMAIHHT 9
           +KM +HH+
Sbjct: 591 AKMLLHHS 598



>NP_001721
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKMAIHH 8
           SK+AIH+
Sbjct: 334 SKLAIHN 340



>NP_001273747
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKMAIHH 8
           SK+AIH+
Sbjct: 243 SKLAIHN 249



>NP_001277137
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 827 SKLFVHH 833



>NP_001277138
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 777 SKLFVHH 783



>NP_001121695
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 827 SKLFVHH 833



>NP_055918
          Length = 1925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/5 (80%), Positives = 5/5 (100%)

Query: 4    MAIHH 8
            MA+HH
Sbjct: 1102 MAVHH 1106



>XP_006719925
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKMAIHH 8
           SK+AIH+
Sbjct: 243 SKLAIHN 249



>XP_005266566
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SKMAIHH 8
           SK+AIH+
Sbjct: 243 SKLAIHN 249



>XP_006712975
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 820 SKLFVHH 826



>XP_006712974
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 827 SKLFVHH 833



>XP_005264770
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 827 SKLFVHH 833



>XP_005264768
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 827 SKLFVHH 833



>XP_005264767
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 827 SKLFVHH 833



>XP_006712973
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   SKMAIHH 8
           SK+ +HH
Sbjct: 827 SKLFVHH 833



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.123    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 513,783
Number of extensions: 550
Number of successful extensions: 39
Number of sequences better than 10000.0: 39
Number of HSP's gapped: 39
Number of HSP's successfully gapped: 39
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)