Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1482
XP_006718908                                                           18    1482
XP_005271621                                                           18    1482
XP_006718907                                                           18    1482
XP_006718906                                                           18    1482
XP_005271619                                                           18    1482
XP_005271618                                                           18    1482
NP_001123498                                                           16    5631
XP_006726518                                                           16    5631
XP_006715991                                                           16    5631
XP_006715990                                                           16    5631
NP_775949                                                              16    5631
NP_001123497                                                           16    5631
NP_001135745                                                           16    7355
NP_001135746                                                           16    7355
NP_001193980                                                           16    7355
NP_056097                                                              16    7355
XP_006712448                                                           16    7355
XP_006712447                                                           16    7355
XP_006712446                                                           16    7355
XP_006712445                                                           16    7355
XP_006712444                                                           16    7355
XP_006712443                                                           16    7355
XP_006712442                                                           16    7355
XP_006712441                                                           16    7355
XP_006712440                                                           16    7355
XP_006712439                                                           16    7355
XP_006712438                                                           16    7355
XP_006712437                                                           16    7355
XP_006712436                                                           16    7355
XP_006725230                                                           15    9605
XP_006720283                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSILARTLK 9
            LSILART K
Sbjct: 2258 LSILARTFK 2266
>XP_006718908
          Length = 1708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           LSILART K
Sbjct: 910 LSILARTFK 918
>XP_005271621
          Length = 2708

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSILARTLK 9
            LSILART K
Sbjct: 1910 LSILARTFK 1918
>XP_006718907
          Length = 3050

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSILARTLK 9
            LSILART K
Sbjct: 2252 LSILARTFK 2260
>XP_006718906
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSILARTLK 9
            LSILART K
Sbjct: 2258 LSILARTFK 2266
>XP_005271619
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSILARTLK 9
            LSILART K
Sbjct: 2258 LSILARTFK 2266
>XP_005271618
          Length = 3056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LSILARTLK 9
            LSILART K
Sbjct: 2258 LSILARTFK 2266
>NP_001123498
          Length = 815

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           LSIL +TLK
Sbjct: 226 LSILPQTLK 234
>XP_006726518
          Length = 694

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           LSIL +TLK
Sbjct: 357 LSILPQTLK 365
>XP_006715991
          Length = 845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           LSIL +TLK
Sbjct: 390 LSILPQTLK 398
>XP_006715990
          Length = 919

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           LSIL +TLK
Sbjct: 390 LSILPQTLK 398
>NP_775949
          Length = 845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           LSIL +TLK
Sbjct: 390 LSILPQTLK 398
>NP_001123497
          Length = 845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           LSIL +TLK
Sbjct: 390 LSILPQTLK 398
>NP_001135745
          Length = 1479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>NP_001135746
          Length = 1471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>NP_001193980
          Length = 1477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>NP_056097
          Length = 1538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712448
          Length = 1255

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 253 ISVLAETIK 261
>XP_006712447
          Length = 1264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 253 ISVLAETIK 261
>XP_006712446
          Length = 1454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712445
          Length = 1462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712444
          Length = 1470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712443
          Length = 1478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712442
          Length = 1478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712441
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712440
          Length = 1487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712439
          Length = 1487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712438
          Length = 1494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712437
          Length = 1494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006712436
          Length = 1495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LSILARTLK 9
           +S+LA T+K
Sbjct: 484 ISVLAETIK 492
>XP_006725230
          Length = 2636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LSILARTLK 9
          LSIL+RT K
Sbjct: 48 LSILSRTGK 56
>XP_006720283
          Length = 2636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LSILARTLK 9
          LSIL+RT K
Sbjct: 48 LSILSRTGK 56
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.139    0.324 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 253,704
Number of extensions: 269
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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